Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jay Well"'
Publikováno v:
Frontiers in Education, Vol 9 (2024)
Rural communities need skilled innovators who engage as community members, support economic opportunities, and develop novel ways to solve local problems. Through innovation, Invention Education (IvE) is one way to promote the creativity and problem-
Externí odkaz:
https://doaj.org/article/aac12f995acb41ddaade87f8ca3b7532
Publikováno v:
Systems, Vol 8, Iss 2, p 11 (2020)
The myriad of problems facing the world today are increasingly complex, dynamic, and transcend multiple domains. This necessitates the need for trans-disciplinary approaches capable of providing a framework to help solve these problems. Systems think
Externí odkaz:
https://doaj.org/article/fcb49cec9e9f41f886709fc01b05b592
Autor:
Gabrielle Scher, Catherine Yankowski, Drishya Kurup, Nicole M. Josleyn, Eric R. Wilkinson, Jay Wells, Jesse Steffens, Ginger Lynn, Sean Vantongeren, Xiankun Zeng, Nancy Twenhafel, Kathleen A. Cashman, Matthias J. Schnell
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-15 (2024)
Abstract Lassa fever virus (LASV), a member of the Arenavirus family, is the etiological agent of Lassa fever, a severe hemorrhagic disease that causes considerable morbidity and mortality in the endemic areas of West Africa. LASV is a rodent-borne C
Externí odkaz:
https://doaj.org/article/ddd6435166dd4c97bc11c151a36f5064
Autor:
Sheli R. Radoshitzky, Patrick Iversen, Xianghan Lu, Jing Zou, Suzanne J. F. Kaptein, Kelly S. Stuthman, Sean A. Van Tongeren, Jesse Steffens, Ruoyu Gong, Hoa Truong, Annapurna A. Sapre, Huiling Yang, Xiaodong Xie, Jia Jun Chia, Zhijuan J. Song, Stacey M. Leventhal, Josolyn Chan, Alex Shornikov, Xin Zhang, David Cowfer, Helen Yu, Travis Warren, Tomas Cihlar, Danielle P. Porter, Johan Neyts, Pei-Yong Shi, Jay Wells, John P. Bilello, Joy Y. Feng
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Remdesivir (GS-5734; VEKLURY) is a single diastereomer monophosphoramidate prodrug of an adenosine analog (GS-441524). Remdesivir is taken up by target cells and metabolized in multiple steps to form the active nucleoside triphosphate (GS-44
Externí odkaz:
https://doaj.org/article/ee7f5fe788f0477a9009a8f32e4eeffd
Autor:
Travis K. Warren, Christopher D. Kane, Jay Wells, Kelly S. Stuthman, Sean A. Van Tongeren, Nicole L. Garza, Ginger Donnelly, Jesse Steffens, Laura Gomba, Jessica M. Weidner, Sarah Norris, Xiankun Zeng, Roy Bannister, Tomas Cihlar, Sina Bavari, Danielle P. Porter, Patrick L. Iversen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Efficacious therapeutics for Ebola virus disease are in great demand. Ebola virus infections mediated by mucosal exposure, and aerosolization in particular, present a novel challenge due to nontypical massive early infection of respiratory l
Externí odkaz:
https://doaj.org/article/8b24a8ac056941f5a1d728fbbaf1db9c
Autor:
Travis Warren, Elizabeth Zumbrun, Jessica M. Weidner, Laura Gomba, Franco Rossi, Roy Bannister, Jacqueline Tarrant, Matthew Reed, Eric Lee, Jo Lynne Raymond, Jay Wells, Joshua Shamblin, Kelly Wetzel, Ginger Donnelly, Sean Van Tongeren, Nicole Lackemeyer, Jesse Steffens, Adrienne Kimmel, Carly Garvey, Holly Bloomfield, Christiana Blair, Bali Singh, Sina Bavari, Tomas Cihlar, Danielle Porter
Publikováno v:
Viruses, Vol 12, Iss 1, p 92 (2020)
Recent Ebola virus (EBOV) outbreaks in West Africa and the Democratic Republic of the Congo have highlighted the urgent need for approval of medical countermeasures for treatment and prevention of EBOV disease (EVD). Until recently, when successes we
Externí odkaz:
https://doaj.org/article/42a5e1bfb28548e7ad26abcaac8bc9f5
Autor:
Travis K Warren, Chris A Whitehouse, Jay Wells, Lisa Welch, Jay S Charleston, Alison Heald, Donald K Nichols, Marc E Mattix, Gustavo Palacios, Jeffrey R Kugleman, Patrick L Iversen, Sina Bavari
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 2, p e0004456 (2016)
Marburg virus (MARV) is an Ebola-like virus in the family Filovirdae that causes sporadic outbreaks of severe hemorrhagic fever with a case fatality rate as high as 90%. AVI-7288, a positively charged antisense phosphorodiamidate morpholino oligomer
Externí odkaz:
https://doaj.org/article/c8b3af9a51de44cb95f7da37c00b05f2
Autor:
Travis K. Warren, Chris A. Whitehouse, Jay Wells, Lisa Welch, Alison E. Heald, Jay S. Charleston, Pete Sazani, St. Patrick Reid, Patrick L. Iversen, Sina Bavari
Publikováno v:
mBio, Vol 6, Iss 1 (2015)
ABSTRACT Ebola viruses (EBOV) cause severe disease in humans and nonhuman primates with high mortality rates and continue to emerge in new geographic locations, including several countries in West Africa, the site of a large ongoing outbreak. Phospho
Externí odkaz:
https://doaj.org/article/19d856969d434bf7a60886a465bb16a6