Zobrazeno 1 - 10
of 247
pro vyhledávání: '"Jay W Fox"'
Autor:
Cristina Herrera, Jéssica Kele A Macêdo, Andrés Feoli, Teresa Escalante, Alexandra Rucavado, José María Gutiérrez, Jay W Fox
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 4, p e0004599 (2016)
The time-course of the pathological effects induced by the venom of the snake Bothrops asper in muscle tissue was investigated by a combination of histology, proteomic analysis of exudates collected in the vicinity of damaged muscle, and immunodetect
Externí odkaz:
https://doaj.org/article/7fccee891585495e9ac093b78093ff1b
Autor:
Cristina Herrera, Teresa Escalante, Mathieu-Benoit Voisin, Alexandra Rucavado, Diego Morazán, Jéssica Kele A Macêdo, Juan J Calvete, Libia Sanz, Sussan Nourshargh, José María Gutiérrez, Jay W Fox
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 4, p e0003731 (2015)
Snake venom hemorrhagic metalloproteinases (SVMPs) of the PI, PII and PIII classes were compared in terms of tissue localization and their ability to hydrolyze basement membrane components in vivo, as well as by a proteomics analysis of exudates coll
Externí odkaz:
https://doaj.org/article/90ea38cdfae14a9db21ab4f409d0b9d3
Autor:
Lucas Tirloni, José Reck, Renata Maria Soares Terra, João Ricardo Martins, Albert Mulenga, Nicholas E Sherman, Jay W Fox, John R Yates, Carlos Termignoni, Antônio F M Pinto, Itabajara da Silva Vaz
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94831 (2014)
The cattle tick Rhipicephalus (Boophilus) microplus is one of the most harmful parasites affecting bovines. Similarly to other hematophagous ectoparasites, R. microplus saliva contains a collection of bioactive compounds that inhibit host defenses ag
Externí odkaz:
https://doaj.org/article/f46329531f5e4959aeb2a1252c86fdba
Autor:
Annelize Z B Aragão, Marília Belloni, Fernando M Simabuco, Mariana R Zanetti, Sami Yokoo, Romênia R Domingues, Rebeca Kawahara, Bianca A Pauletti, Anderson Gonçalves, Michelle Agostini, Edgard Graner, Ricardo D Coletta, Jay W Fox, Adriana F Paes Leme
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43521 (2012)
The extracellular milieu is comprised in part by products of cellular secretion and cell surface shedding. The presence of such molecules of the sheddome and secretome in the context of the extracellular milieu may have important clinical implication
Externí odkaz:
https://doaj.org/article/29370448a80f4c2fb0209ca49354c931
Autor:
Robert W Tilghman, Edik M Blais, Catharine R Cowan, Nicholas E Sherman, Pablo R Grigera, Erin D Jeffery, Jay W Fox, Brett R Blackman, Daniel J Tschumperlin, Jason A Papin, J Thomas Parsons
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37231 (2012)
Tumor cells in vivo encounter diverse types of microenvironments both at the site of the primary tumor and at sites of distant metastases. Understanding how the various mechanical properties of these microenvironments affect the biology of tumor cell
Externí odkaz:
https://doaj.org/article/673a17e071dc46ae9e1ff2e9ef483c46
Autor:
Teresa Escalante, Natalia Ortiz, Alexandra Rucavado, Eladio F Sanchez, Michael Richardson, Jay W Fox, José María Gutiérrez
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28017 (2011)
Hemorrhage is a clinically important manifestation of viperid snakebite envenomings, and is induced by snake venom metalloproteinases (SVMPs). Hemorrhagic and non-hemorrhagic SVMPs hydrolyze some basement membrane (BM) and associated extracellular ma
Externí odkaz:
https://doaj.org/article/1ac8bdf79d90437e82e7666df091b4ca
Autor:
Ana Karina de Oliveira, Alexandra Rucavado, Teresa Escalante, José María Gutiérrez, Jay W. Fox
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 278 (2024)
Viperid snake venoms induce severe tissue damage, characterized by the direct toxic action of venom components, i.e., phospholipases A2 (PLA2s) and metalloproteinases (SVMPs), concomitantly with the onset of endogenous inflammatory processes, in an i
Externí odkaz:
https://doaj.org/article/0ed0472411ce41e8948baaab81aee1db
Autor:
Ana K. de Oliveira, Patcharin Pramoonjago, Alexandra Rucavado, Christopher Moskaluk, Dilza T. Silva, Teresa Escalante, José María Gutiérrez, Jay W. Fox
Publikováno v:
Toxins, Vol 15, Iss 3, p 208 (2023)
Pathological and inflammatory events in muscle after the injection of snake venoms vary in different regions of the affected tissue and at different time intervals. In order to study such heterogeneity in the immune cell microenvironment, a murine mo
Externí odkaz:
https://doaj.org/article/29013a0aaa9848e186d6a4c62b2bcd61
Autor:
Jamie L. Null, Dae Joong Kim, James V. McCann, Patcharin Pramoonjago, Jay W. Fox, Jianhao Zeng, Pankaj Kumar, Lincy Edatt, Chad V. Pecot, Andrew C. Dudley
Publikováno v:
Cancer Research.
Cancer cell dissemination to sentinel lymph nodes associates with poor patient outcomes, particularly in breast cancer. The process by which cancer cells egress from the primary tumor upon interfacing with the lymphatic vasculature is complex and dri
Publikováno v:
Toxins; Volume 14; Issue 10; Pages: 657
Longitudinal metabolomics and lipidomics analyses were carried out on the blood plasma of mice injected intramuscularly with venoms of the viperid species Bothrops asper or Daboia russelii. Blood samples were collected 1, 3, 6, and 24 h after venom i