Zobrazeno 1 - 10
of 201
pro vyhledávání: '"Jay W, Mason"'
Publikováno v:
Clinical and Translational Science, Vol 12, Iss 3, Pp 257-266 (2019)
Since introduction of the International Conference on Harmonization proarrhythmia guidelines in 2005, no new marketed drugs have been associated with unacceptable risk of Torsade de Pointes. Although cardiac safety improved, these guidelines had the
Externí odkaz:
https://doaj.org/article/31731ac8df80477d81a6259f9f588f48
Publikováno v:
Clinical and Translational Science, Vol 12, Iss 1, Pp 47-52 (2019)
The purpose of this study was to measure the electrocardiographic (ECG) effects of WCK 2349 (the L‐alanine ester prodrug of levonadifloxacin) at a supratherapeutic oral dose of 2,600 mg. A total of 48 healthy volunteers were randomized to treatment
Externí odkaz:
https://doaj.org/article/65032b2fa36a44a1ae8231c6c846975d
Correction: Electrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Current Block.
Autor:
Jose Vicente, Lars Johannesen, Meisam Hosseini, Jay W Mason, Philip T Sager, Esther Pueyo, David G Strauss
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197952 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0163619.].
Externí odkaz:
https://doaj.org/article/989426972b544a98bcaf026c2ec3d4cc
Publikováno v:
Journal of Child and Adolescent Psychopharmacology
Objectives: Our research aims were to determine if repolarization measures (QTcF, QTcB, JTcF, and JTcB) in attention-deficit/hyperactivity disorder (ADHD) children and adolescents differ from normal subjects and determine if the JTc interval duration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a01f894bab29686581d53ac0e0ca21e7
http://europepmc.org/articles/PMC8066348
http://europepmc.org/articles/PMC8066348
Autor:
Jose Vicente, Lars Johannesen, Meisam Hosseini, Jay W Mason, Philip T Sager, Esther Pueyo, David G Strauss
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0163619 (2016)
Drugs that prolong the heart rate corrected QT interval (QTc) on the electrocardiogram (ECG) by blocking the hERG potassium channel and also block inward currents (late sodium or L-type calcium) are not associated with torsade de pointes (e.g. ranola
Externí odkaz:
https://doaj.org/article/fc0f1c6356e94f23ac01ff3231f2fc02
Autor:
Jay W. Mason, Thomas E. Moon
Publikováno v:
Antibiotics, Vol 6, Iss 1, p 5 (2017)
(1) Background: We assessed the effect of moxifloxacin on heart rate, and reviewed the heart rate effects of other antibiotics; (2) Methods: A total of 335 normal volunteers had 12-lead electrocardiograms recorded at multiple time points before and d
Externí odkaz:
https://doaj.org/article/85a8880ac6534f61b4d67ae42ba89168
Publikováno v:
Clinical and Translational Science
Clinical and Translational Science, Vol 12, Iss 1, Pp 47-52 (2019)
Clinical and Translational Science, Vol 12, Iss 1, Pp 47-52 (2019)
The purpose of this study was to measure the electrocardiographic (ECG) effects of WCK 2349 (the L‐alanine ester prodrug of levonadifloxacin) at a supratherapeutic oral dose of 2,600 mg. A total of 48 healthy volunteers were randomized to treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a913424bc1ac98e836293f3060814fb
http://europepmc.org/articles/PMC6342240
http://europepmc.org/articles/PMC6342240
Publikováno v:
Circulation: Arrhythmia and Electrophysiology. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f0c6544f2b581835f0b221d866daf5
https://doi.org/10.1161/circep.120.009017
https://doi.org/10.1161/circep.120.009017
Autor:
Jay W. Mason, Heinz-Peter Schultheiss
Myocarditis can be acute, subacute, or chronic and may affect either focal or diffuse areas of the myocardium. It has many infectious and non-infectious aetiologies, but viral infections are the main cause in most regions, with notable exceptions suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66c178642e492ee3980a7047a6f4ab73
https://doi.org/10.1093/med/9780198746690.003.0353
https://doi.org/10.1093/med/9780198746690.003.0353
Autor:
Steven Tracy, Nora M. Chapman, Vernon Hartz, Jay W. Mason, Akira Matsumori, Miho Shimada, Toshio Shimada, Eiji Nakatani, Mark T. Drayson
Publikováno v:
Clinical immunology (Orlando, Fla.). 217
Background In this study, we measured immunoglobulin free light chains (FLC), a biomarker of inflammation in the sera of patients with heart failure due to myocarditis. Methods FLC kappa and FLC lambda were assayed in stored serum samples from patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7120bfddcb36619d8018c82f915f3c56
https://pubmed.ncbi.nlm.nih.gov/32479987
https://pubmed.ncbi.nlm.nih.gov/32479987