Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jay T. Goodwin"'
Autor:
Veerabahu Shanmugasundaram, Jürgen Bajorath, Ralph E. Christoffersen, James D. Petke, W. Jeffrey Howe, Mark A. Johnson, Dimitris K. Agrafiotis, Pil Lee, Leslie A. Kuhn, Jay T. Goodwin, M. Katharine Holloway, Thompson N. Doman, W. Patrick Walters, Suzanne Schreyer, José L. Medina-Franco, Karina Martinez-Mayorga, Linda L. Restifo
Publikováno v:
Journal of Computer-Aided Molecular Design. 36:623-638
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4fcd4233176dd82476c1a8cc7e31cb1
https://doi.org/10.1007/s10822-022-00473-2
https://doi.org/10.1007/s10822-022-00473-2
Publikováno v:
Chemical Science
Progressive solute-rich polymer phase transitions provide pathways for achieving ordered supramolecular assemblies. Intrinsically disordered protein domains specifically regulate information in biological networks via conformational ordering. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9688a8271671d71a772f82df38174e2
https://doi.org/10.1039/d0sc03666h
https://doi.org/10.1039/d0sc03666h
Publikováno v:
Journal of Chemical Information and Modeling. 59:4266-4277
Biology encodes hereditary information in DNA and RNA, which are finely tuned to their biological functions and modes of biological production. The central role of nucleic acids in biological information flow makes them key targets of pharmaceutical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c84c050ed639570dd4be9f110c2964
https://doi.org/10.1021/acs.jcim.9b00632
https://doi.org/10.1021/acs.jcim.9b00632
Progressive solute-rich polymer phase transitions provide pathways for achieving ordered supramolecular assemblies. Intrinsically disordered protein domains specifically regulate information in biological networks via conformational ordering. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19147982f0af4594d4ad4f434be92f9e
https://doi.org/10.26434/chemrxiv.12698138.v1
https://doi.org/10.26434/chemrxiv.12698138.v1
Publikováno v:
Astrobiology
Ribonucleic acid (RNA) is one of the two nucleic acids used by extant biochemistry and plays a central role as the intermediary carrier of genetic information in transcription and translation. If RNA was involved in the origin of life, it should have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22bc7ab0f0738f25aa6f392d3d23bbd2
https://doi.org/10.1089/ast.2014.1213
https://doi.org/10.1089/ast.2014.1213
Autor:
Martha A. Grover, Tolulope O. Omosun, David G. Lynn, Ming-Chien Hsieh, Chenrui Chen, Jay T. Goodwin, Anil K. Mehta, Allisandra K. Rha, Olga Taran
Publikováno v:
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences. 375(2109)
The RNA world hypothesis simplifies the complex biopolymer networks underlining the informational and metabolic needs of living systems to a single biopolymer scaffold. This simplification requires abiotic reaction cascades for the construction of RN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e151f61449c3b4dd87f347590d4f3f0
https://pubmed.ncbi.nlm.nih.gov/29133453
https://pubmed.ncbi.nlm.nih.gov/29133453
Autor:
George F. R. Ellis, Jillian E. Smith-Carpenter, Anil K. Mehta, Sara Imari Walker, Sha Li, Jay T. Goodwin, Paul Davies, David G. Lynn
Publikováno v:
From Matter to Life: Information and Causality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e925084dca088c08a3b15b2f73b2b8a8
https://doi.org/10.1017/9781316584200.005
https://doi.org/10.1017/9781316584200.005
Publikováno v:
Accounts of Chemical Research. 45:2189-2199
Living matter is the most elaborate, elegant, and complex hierarchical material known and is consequently the natural target for an ever-expanding scientific and technological effort to unlock and deconvolute its marvelous forms and functions. Our cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125f392a1eac04ebbe40be9777070458
https://doi.org/10.1021/ar300214w
https://doi.org/10.1021/ar300214w
Autor:
David G. Lynn, Chenrui Chen, Anil K. Mehta, Ting Pan, Ming-Chien Hsieh, Martha A. Grover, Jay T. Goodwin, Junjun Tan
Publikováno v:
Nature chemistry. 9(8)
Template-directed polymerization reactions enable the accurate storage and processing of nature's biopolymer information. This mutualistic relationship of nucleic acids and proteins, a network known as life's central dogma, is now marvellously comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b1dc789905cbe6f620ae73ab6158b9
https://pubmed.ncbi.nlm.nih.gov/28754943
https://pubmed.ncbi.nlm.nih.gov/28754943
Autor:
Jay T, Goodwin, David G, Lynn
Publikováno v:
Angewandte Chemie (International ed. in English). 53(27)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eed29f270764e38d324425f7d005a468
https://pubmed.ncbi.nlm.nih.gov/24828483
https://pubmed.ncbi.nlm.nih.gov/24828483