Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jay Small"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract Dominance hierarchies often form between species, especially at common feeding locations. Yet, relative to work focused on the factors that maintain stable dominance hierarchies within species, large-scale analyses of interspecific dominance
Externí odkaz:
https://doaj.org/article/a2342ba014ba40b2b405febf1878ce85
Autor:
Tanya Jindal, Xiaolin Zhu, Li Zhang, Kevin R Reyes, Prianka Deshmukh, Ivan de Kouchkovsky, Vipul Kumar, Edward Maldonado, Chase Shipp, Daniel H Kwon, Hala Borno, Rohit Bose, Arpita Desai, Rahul Raj Aggarwal, Sima P. Porten, Eric Jay Small, Lawrence Fong, Jonathan Chou, Terence W. Friedlander, Vadim S Koshkin
Publikováno v:
Journal of Clinical Oncology. 41:534-534
534 Background: ICIs are frequently used as therapy in mUC, but only a minority of patients (pts) respond to treatment. High TMB is associated with improved outcomes to ICIs. However, much is unknown about biomarkers associated with ICI outcomes in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba4d8928b2d85ef01b26bc44730fd0f8
https://doi.org/10.1200/jco.2023.41.6_suppl.534
https://doi.org/10.1200/jco.2023.41.6_suppl.534
Autor:
Annelise Thorn, Kelly Gordon, Barry Tong, Daniel H Kwon, Mallika Sachdev Dhawan, Hala Borno, Rahul Raj Aggarwal, Eric Jay Small, Amie Blanco
Publikováno v:
Journal of Clinical Oncology. 41:112-112
112 Background: A remote Genetic Testing Station (GTS) workflow was implemented at an academic medical institution to expand access to genetic testing for patients with prostate cancer. During a telephone appointment, a genetic counselor assistant co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b2fae360a4be289981471dc550b165e
https://doi.org/10.1200/jco.2023.41.6_suppl.112
https://doi.org/10.1200/jco.2023.41.6_suppl.112
Autor:
Stephane Oudard, Boris A. Hadaschik, Laurent Antoni, Joris Diels, Irene Luccarini, Pushpike Thilakarathne, Matthew Raymond Smith, Eric Jay Small
Publikováno v:
Journal of Clinical Oncology. 41:157-157
157 Background: Apalutamide (Apa) delays the onset of metastases and extends survival in nmCRPC. However, the benefit of subsequent therapy for metastatic castration resistant prostate cancer (mCRPC) following progression on Apa remains inadequately
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2916478c3952621a05fdca87c3665c4b
https://doi.org/10.1200/jco.2023.41.6_suppl.157
https://doi.org/10.1200/jco.2023.41.6_suppl.157
Autor:
Eleni Efstathiou, Matthew Raymond Smith, Shahneen Sandhu, Gerhardt Attard, Marniza Saad, David Olmos, Elena Castro, Guilhem Roubaud, Andrea Juliana Gomes, Eric Jay Small, Dana E. Rathkopf, Howard Gurney, Wonho Jung, Gary Mason, Peter St. John Francis, George C. Wang, Daphne Wu, Brooke Diorio, Angela Mennicke Lopez- Gitlitz, Kim N. Chi
Publikováno v:
Journal of Clinical Oncology. 41:170-170
170 Background: In the primary analysis of the phase 3 MAGNITUDE study, NIRA/AAP significantly improved outcomes in pts with mCRPC and HRR gene alterations. Here, we report results from IA2 of secondary endpoints in MAGNITUDE. Methods: 423 eligible p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a63890d5b4c0a6bd5465627591f8e821
https://doi.org/10.1200/jco.2023.41.6_suppl.170
https://doi.org/10.1200/jco.2023.41.6_suppl.170
Autor:
Elena Castro, Kim N. Chi, Shahneen Sandhu, David Olmos, Gerhardt Attard, Marniza Saad, Andrea Juliana Gomes, Dana E. Rathkopf, Matthew Raymond Smith, Taek Won Kang, Felipe Melo Cruz, Umberto Basso, Gary Mason, Adam del Corral, Shiva Dibaj, Daphne Wu, Brooke Diorio, Angela Mennicke Lopez- Gitlitz, Deniz Tural, Eric Jay Small
Publikováno v:
Journal of Clinical Oncology. 41:172-172
172 Background: NIRA/AAP significantly improved outcomes in pts with mCRPC and HRR gene alterations, particularly in BRCA, in the phase 3 MAGNITUDE study. As a practical measure, pts were permitted to receive up to 4 mos of AAP (in 1L mCRPC) prior to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a486e02ca2104ffdb5bf07babb7fc10
https://doi.org/10.1200/jco.2023.41.6_suppl.172
https://doi.org/10.1200/jco.2023.41.6_suppl.172
Autor:
Christina Phuong, Amy M. Lin, Izzy Friesner, Lisa Ni, Rahul Raj Aggarwal, Hala Borno, Vadim S Koshkin, Arpita Desai, Terence W. Friedlander, Lawrence Fong, Rohit Bose, Jonathan Chou, Tammy J. Rodvelt, Osama Mohamad, Anthony C. Wong, Felix Y Feng, Eric Jay Small, Julian C. Hong
Publikováno v:
Journal of Clinical Oncology. 40:397-397
397 Background: Real-world data (RWD) is playing an increasingly important role in cancer research. Surrogate endpoints such as metastasis-free survival play an important role in prostate cancer research, leading to interest in its computational extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1f987230993e24242cc749c2f5e9ea8
https://doi.org/10.1200/jco.2022.40.28_suppl.397
https://doi.org/10.1200/jco.2022.40.28_suppl.397
Autor:
Dana E. Rathkopf, Guilhem Roubaud, Kim N. Chi, Shahneen Sandhu, Eleni Efstathiou, Gerhardt Attard, David Olmos, Ji Youl Lee, Eric Jay Small, Andrea Juliana Gomes, Marniza Saad, Elena Castro, Deniz Tural, Gary Mason, Katherine B. Bevans, Jeremiah Trudeau, Peter St. John Francis, George C. Wang, Angela Lopez-Gitlitz, Matthew Raymond Smith
Publikováno v:
Journal of Clinical Oncology. 40:5060-5060
5060 Background: Results from the international, randomized, double-blind, phase 3 MAGNITUDE study demonstrated that NIRA + AAP improved radiographic progression-free survival, time to cytotoxic chemotherapy, and time to symptomatic progression, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef38a36af28b205c14d7a2d9b625c92d
https://doi.org/10.1200/jco.2022.40.16_suppl.5060
https://doi.org/10.1200/jco.2022.40.16_suppl.5060
Autor:
Rahul Raj Aggarwal, Jacqueline Vuky, David James VanderWeele, Matthew Rettig, Elisabeth I. Heath, Tomasz M. Beer, Jiaoti Huang, Nela Pawlowska, Ryan Sinit, Jill Abbey, Bin Liu, Marc Nasoff, Andrew Dorr, Eric Jay Small
Publikováno v:
Journal of Clinical Oncology. 40:3001-3001
3001 Background: FOR46, a fully human antibody (ab) conjugated to monomethyl auristatin E (MMAE), targets a tumor selective epitope of CD46, which is highly expressed in mCRPC and treatment-emergent small cell neuroendocrine cancer (t-SCNC). CD46 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8799ed96afdfce74c107bb3046c8450f
https://doi.org/10.1200/jco.2022.40.16_suppl.3001
https://doi.org/10.1200/jco.2022.40.16_suppl.3001
Autor:
Shahneen Sandhu, Gerhardt Attard, David Olmos, Eleni Efstathiou, Elena Castro, Dana E. Rathkopf, Matthew Raymond Smith, Guilhem Roubaud, Eric Jay Small, Andrea Juliana Gomes, Marniza Saad, Deniz Tural, Shibu Thomas, Karen Urtishak, Michael Gormley, Gary Mason, Brooke Diorio, George C. Wang, Angela Lopez-Gitlitz, Kim N. Chi
Publikováno v:
Journal of Clinical Oncology. 40:5020-5020
5020 Background: NIRA + AAP significantly improved outcomes in pts with mCRPC and HRR gene alterations in the Phase 3 MAGNTUDE study. There is a paucity of data supporting use of PARP inhibitors in pts with HRR gene alterations other than BRCA1/2. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1273ed1557a1d885e337eb6ca10719e
https://doi.org/10.1200/jco.2022.40.16_suppl.5020
https://doi.org/10.1200/jco.2022.40.16_suppl.5020