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Autor:
Jeffrey N. McKnight, Toshio Tsukiyama, Tsung-Han Hsieh, Tianhong Fu, Jay Schendure, Sarah G. Swygert, Xiaoying Wu, Seungsoo Kim, Robert N. Eisenman, Oliver J. Rando
SUMMARYQuiescence is a stress-resistant state in which cells reversibly exit the mitotic cell cycle and suspend most cellular processes. Quiescence is essential for stem cell maintenance and its misregulation is implicated in tumor formation. One of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c772018afee13f3873867cb32766698
Autor:
Joel B. Berletch, William Stafford Noble, Xinxian Deng, Ruolan Qui, Giancarlo Bonora, Vijay Ramani, Christine M. Disteche, Jay Schendure, Gala N Filippova, He Fang, Zhijun Duan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications
Nature Communications
The mammalian inactive X chromosome (Xi) condenses into a bipartite structure with two superdomains of frequent long-range contacts, separated by a hinge region. Using Hi-C in edited mouse cells with allelic deletions or inversions within the hinge,