Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Jay S, Naik"'
Publikováno v:
Antioxidants, Vol 11, Iss 9, p 1680 (2022)
H2S is a gaseous signaling molecule enzymatically produced in mammals and H2S-producing enzymes are expressed throughout the vascular wall. We previously reported that H2S-induced vasodilation is mediated through transient receptor potential cation c
Externí odkaz:
https://doaj.org/article/cf7eeaf4d0df4f37a75e89cc805ce490
Autor:
Alex E. Mohr, Rebecca A. Reiss, Monique Beaudet, Johnny Sena, Jay S. Naik, Benjimen R. Walker, Karen L. Sweazea
Publikováno v:
PeerJ, Vol 9, p e11714 (2021)
Background Diet-induced metabolic dysfunction precedes multiple disease states including diabetes, heart disease, and vascular dysfunction. The critical role of the vasculature in disease progression is established, yet the details of how gene expres
Externí odkaz:
https://doaj.org/article/b100daa201484591a3ede30ad1bf5b74
Autor:
Jacob R. Anderson, Emily E. Morin, Kathryn J. Brayer, Sophia Salbato, Laura V. Gonzalez Bosc, Nancy L. Kanagy, Jay S. Naik
Publikováno v:
Physiological Genomics. 55:179-193
The endothelium contains morphologically similar cells throughout the vasculature, but individual cells along the length of a single vascular tree or in different regional circulations function dissimilarly. When observations made in large arteries a
Publikováno v:
J Physiol
Pulmonary hypertension is characterized by sustained vasoconstriction and remodelling of the small pulmonary arteries, which is associated with persistent depolarization of the resting membrane potential (Em ) of pulmonary arterial smooth muscle cell
Autor:
Amy S. Gardiner, Aleksandr Birg, Jay S. Naik, Nancy L. Kanagy, Laura V. Gonzalez Bosc, Perenkita J Mendiola
Publikováno v:
Comprehensive Physiology. :2467-2488
Hydrogen sulfide (H2 S) is a small, gaseous molecule with poor solubility in water that is generated by multiple pathways in many species including humans. It acts as a signaling molecule in many tissues with both beneficial and pathological effects.
Autor:
Joshua M. Garcia, Perenkita J Mendiola, Gisel Fregoso, Laura V. Gonzalez Bosc, Nancy L. Kanagy, Humberto Morales-Loredo, Carolyn E. Pace, Jay S. Naik, Adelaeda Barrera
Publikováno v:
Am J Physiol Heart Circ Physiol
In sleep apnea, airway obstruction causes intermittent hypoxia (IH). In animal studies, IH-dependent hypertension is associated with loss of vasodilator hydrogen sulfide (H(2)S), and increased H(2)S activation of sympathetic nervous system (SNS) acti
Publikováno v:
Microcirculation (New York, N.Y. : 1994)REFERENCES. 29(4-5)
Our previous work demonstrated that endothelial cell (EC) membrane cholesterol is reduced following 48 h of chronic hypoxia (CH). CH couples endothelial transient receptor potential subfamily V member 4 (TRPV4) channels to muscarinic receptor signali
Publikováno v:
The FASEB Journal. 36
Publikováno v:
The FASEB Journal. 36
Publikováno v:
The FASEB Journal. 36