Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Jay Philip O'brien"'
Publikováno v:
ChemInform. 22
Diastereomeric cis- and trans-tetrahydro-4-aryl-3-[(dimethylamino)methyl]-2H-pyranols derived from 3-[(dimethylamino)methyl]tetrahydro-4H-pyran-4-one (5), have been prepared and their configurations were established on the basis of ir data. The biolo
Autor:
Erno Mohacsi, Jay Philip O'brien
Publikováno v:
ChemInform. 22
O-Demethylation of (9S,13S,14S)-3-methoxy-17- methylmorphinan-10-one (2) to (9S,13S,14S)-3-hydroxy-17-methylmorphinan- 10-one (3) and reduction of 3 to 10α- and 10β-hydroxylated morphinans 4 and 5, are described. The stereochemistry of these epimer
Publikováno v:
ChemInform. 23
Reaction of 2-aminoethanethiol (3) with trans-3-(p-methoxyplienyl)glycidate (4) gave the rac.-cis-1,4-thiazepinone 5 and a by-product 6. The structure of 5 was proven by X-ray crystallography. The X-ray data revealed that this compound adopts the cha
Publikováno v:
Journal of Heterocyclic Chemistry. 29:193-197
Reaction of 2-aminoethanethiol (3) with trans-3-(p-methoxyplienyl)glycidate (4) gave the rac.-cis-1,4-thiazepinone 5 and a by-product 6. The structure of 5 was proven by X-ray crystallography. The X-ray data revealed that this compound adopts the cha
Autor:
David L. Coffen, Alan Schwartz, Jay Philip O'brien, Pradeep B. Madan, Erno Mohacsi, Louis J. Todaro
Publikováno v:
The Journal of Organic Chemistry. 57:851-856
Publikováno v:
Journal of Heterocyclic Chemistry. 27:1623-1628
Diastereomeric cis- and trans-tetrahydro-4-aryl-3-[(dimethylamino)methyl]-2H-pyranols derived from 3-[(dimethylamino)methyl]tetrahydro-4H-pyran-4-one (5), have been prepared and their configurations were established on the basis of ir data. The biolo
Publikováno v:
Journal of Heterocyclic Chemistry. 27:1085-1089
The base catalyzed reaction of 2-aminoethanethiol (3) with trans-3-(p-methoxyphenyl)glycidate (4) gave a mixture of isomeric lactams 5 and 6, and in addition, a by-product 7. The structures of these isomers were proven by X-ray crystallography. The d
Autor:
Erno Mohacsi, Jay Philip O'brien
Publikováno v:
Journal of Heterocyclic Chemistry. 28:93-95
O-Demethylation of (9S,13S,14S)-3-methoxy-17- methylmorphinan-10-one (2) to (9S,13S,14S)-3-hydroxy-17-methylmorphinan- 10-one (3) and reduction of 3 to 10α- and 10β-hydroxylated morphinans 4 and 5, are described. The stereochemistry of these epimer
Publikováno v:
ChemInform. 21
The base catalyzed reaction of 2-aminoethanethiol (3) with trans-3-(p-methoxyphenyl)glycidate (4) gave a mixture of isomeric lactams 5 and 6, and in addition, a by-product 7. The structures of these isomers were proven by X-ray crystallography. The d
Autor:
Erno Mohacsi, Jay Philip O'brien
Publikováno v:
Journal of Heterocyclic Chemistry. 28:2051-2052
The base-catalyzed alkylation of rac.-trans-tetrahydro-6-hydroxy-7-(4-methoxyphenyl)-1,4-thiazepin-5(2H)-one (1) with dimethylaminoethyl chloride in dimethyl sulfoxide provided predominantly rac.-trans-tetrahydro-6-hydroxy-4-[(2-dimethylamino)ethyl]-