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pro vyhledávání: '"Jay P. Overholser"'
Publikováno v:
Cancer. 89:74-82
BACKGROUND Pancreatic carcinoma is associated with a poor prognosis, and treatment options for patients with this disease are limited. The epidermal growth factor (EGF) receptor and its ligands are overexpressed in human pancreatic carcinoma and may
Autor:
Yong-Ching Yang, Elaine J. Derbyshire, Philip E. Thorpe, Jay P. Overholser, Georgina A. Comin, Linda Watkins
Publikováno v:
International journal of cancer. 63(5)
Heparin-steroid conjugates have been prepared by linking a non-anti-coagulating derivative of heparin, which binds to endothelial cells, to an angiostatic steroid, which suppresses endothelial cell division. One such conjugate, heparin adipic hydrazi
Publikováno v:
Cell biophysics.
Immunotoxins and other antibody-based therapeutic reagents have proved effective agonist lymphomas and leukemias, but results with carcinomas and other solid tumors have thus far been less impressive. A major reason for this difference is that macrom
Publikováno v:
Journal of Immunotherapy. 13:57