Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jay Lichter"'
Autor:
Mitsuyuki Matsumoto, Shanni Yamaki, Roghiye Kazimi, Atsuo Kanno, Masashi Maeda, Satoshi Kubo, Mathew Mitchell, Jay Lichter
Publikováno v:
Monday, April 24.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a5e9878aafa234e8634d89ee5642709
https://doi.org/10.1212/wnl.0000000000202027
https://doi.org/10.1212/wnl.0000000000202027
Publikováno v:
Retina. 33:498-507
Excessive accumulation of retinol-based toxins has been implicated in the pathogenesis of geographic atrophy (GA). Fenretinide, an orally available drug that reduces retinol delivery to the eye through antagonism of serum retinol-binding protein (RBP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569017dfb5cef1261b59c4eac22569dd
https://doi.org/10.1097/iae.0b013e318265801d
https://doi.org/10.1097/iae.0b013e318265801d
Autor:
Xiaobo Wang, Fabrice Piu, Richard A. Altschuler, Carl Lebel, Anne Harrop, David F. Dolan, Qiang Ye, Jenifer Sweet, Jay Lichter, Luis A. Dellamary, Rachel Tapp, Rayne Fernandez
Publikováno v:
Otology & Neurotology. 32:171-179
Hypothesis To investigate whether OTO-104, a poloxamer-based hydrogel containing micronized dexamethasone for intratympanic delivery, can provide long-lasting inner ear exposure and be well tolerated. Methods OTO-104 was administered intratympanicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5fa623e63866dc0f434d8303ce6aaa0
https://doi.org/10.1097/mao.0b013e3182009d29
https://doi.org/10.1097/mao.0b013e3182009d29
Autor:
Kimanh D. Nguyen, Andrew Chang, Michael J. McKenna, Jeffrey P. Harris, Luis A. Dellamary, Rachael T. Richardson, Amanda Hu, Sangeeta Maini, Carl Lebel, Halina Lisnichuk, Lloyd B. Minor, Dennis R. Trune, Thomas R. Van De Water, Hayden Eastwood, Erin E. Leary Swan, Anne Harrop, Xiaobo Wang, David Sly, Sarah L. Tao, Jason O. Fiering, Jay Lichter, Charles C. Della Santina, John P. Carey, Alec N. Salt, William F. Sewell, Stefan K. Plontke, Fabrice Piu, Darren Pinder, Sharon G. Kujawa, Elizabeth M. Keithley, Mark M. Mescher, David E. James, Stephen O'Leary, Tim Connolly, Ophir Handzel, J. Beth Kempton, Marcello Peppi, Zhiqiang Chen, Jeffrey T. Borenstein, Maria Holmboe, Gordana Kel, Ernest S. Kim, Qiang Ye, Lorne S. Parnes, Rayne Fernandez, Christine T. Dinh, Brian R. Murphy
Publikováno v:
Audiology and Neurotology. 14:I-IV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf592ea64c1387c0354d82d24014db7f
https://doi.org/10.1159/000259790
https://doi.org/10.1159/000259790
Autor:
Janice H Kurth, Jay Lichter
Publikováno v:
Current Opinion in Biotechnology. 8:692-695
Pharmacogenetics has been promoted as potentially providing benefits to patients, managed care organizations and pharmaceutical companies. This has not translated into products that benecit healthcare developers, providers or consumers. The reasons f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0115d19268f72deeb1b00ebe1e874f
https://doi.org/10.1016/s0958-1669(97)80121-8
https://doi.org/10.1016/s0958-1669(97)80121-8
Autor:
Dieter B. Wildenauer, Sibylle G. Schwab, Margot Albus, Joachim Hallmayer, Bernard Lerer, Wolfgang Maier, Douglas Blackwood, Walter Muir, David St Clair, Stewart Morris, Hans W. Moises, Liu Yang, Helgi Kristbjarnarson, Tomas Helgason, Claudia Wiese, David A. Collier, Peter Holmans, Jo Daniels, Mark Rees, Philip Asherson, Queta Roberts, Alastair Cardno, Maria J. Arranz, Homero Vallada, David Ball, Hiroshi Kunugi, Robin M. Murray, John F. Powell, Sin Nanko, Pak Sham, Mike Gill, Peter McGuffin, Michael J. Owen, Ann E. Pulver, Stylianos E. Antonarakis, Robert Babb, Jean-Louis Blouin, Nicola DeMarchi, Beth Dombroski, David Housman, Maria Karayiorgou, Jurg Ott, Laura Kasch, Haig Kazazian, Virginia K. Lasseter, Erika Loetscher, Hermann Luebbert, Gerald Nestadt, Carl Ton, Paula S. Wolyniec, Claudine Laurent, Michel de Chaldee, Florence Thibaut, Maurice Jay, Daniele Samolyk, Michel Petit, Dominique Campion, Jacques Mallet, Richard E. Straub, Charles J. MacLean, Stephen M. Easter, F. Anthony O'Neill, Dermot Walsh, Kenneth S. Kendler, Pablo V. Gejman, Qiuhe Cao, Elliot Gershon, Judith Badner, Ethiopia Beshah, Jing Zhang, Brien P. Riley, Swarnageetha Rajagopalan, Mpala Mogudi-Carter, Trefor Jenkins, Robert Williamson, Lynn E. DeLisi, Chad Garner, Mary Kelly, Carrie LeDuc, Lon Cardon, Jay Lichter, Tim Harris, Josephine Loftus, Gail Shields, Margarite Comasi, Antonio Vita, Angela Smith, Jay Dann, Geoff Joslyn, Hugh Gurling, Gursharan Kalsi, Jon Brynjolfsson, David Curtis, Thordur Sigmundsson, Robert Butler, Tim Read, Patrice Murphy, Andrew Chih-Hui Chen, Hannes Petursson, Bill Byerley, Mark Hoff, John Holik, Hilary Coon, Douglas F. Levinson, Derek J. Nancarrow, Raymond R. Crowe, Nancy Andreasen, Jeremy M. Silverman, Richard C. Mohs, Larry J. Siever, Jean Endicott, Lawrence Sharpe, Marilyn K. Walters, David P. Lennon, Nicholas K. Hayward, Lodewijk A. Sandkuijl, Bryan J. Mowry, Harald N. Aschauer, Kurt Meszaros, Elisabeth Lenzinger, Karoline Fuchs, Angela M. Heiden, Leonid Kruglyak, Mark J. Daly, Tara C. Matise
Publikováno v:
American Journal of Medical Genetics. 67:580-594
In response to reported schizophrenia linkage findings on chromosomes 3, 6 and 8, fourteen research groups genotyped 14 microsatellite markers in an unbiased, collaborative (New) sample of 403-567 informative pedigrees per marker, and in the Original
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eed6167e4522c861b0fa99357177409
https://doi.org/10.1002/(sici)1096-8628(19961122)67:6<580::aid-ajmg11>3.0.co
https://doi.org/10.1002/(sici)1096-8628(19961122)67:6<580::aid-ajmg11>3.0.co
Pharmacokinetics of dexamethasone solution following intratympanic injection in guinea pig and sheep
Autor:
Carl Lebel, Anne Harrop, Xiaobo Wang, Rayne Fernandez, Jay Lichter, David Lau, Fabrice Piu, Qiang Ye, Luis A. Dellamary
Publikováno v:
Audiologyneuro-otology. 16(4)
Information on inner ear pharmacokinetics is limited in the literature, especially in large animals and in humans. A preliminary study was designed to explore the differences in inner ear exposure between guinea pigs and sheep following a single intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fd8b8a3afe1a12f3f46dff3795f0321
https://pubmed.ncbi.nlm.nih.gov/20980743
https://pubmed.ncbi.nlm.nih.gov/20980743
Autor:
Luis A. Dellamary, Rayne Fernandez, Carl Lebel, Jeffrey P. Harris, Xiaobo Wang, Fabrice Piu, Anne Harrop, Qiang Ye, Elizabeth M. Keithley, Jay Lichter
Publikováno v:
Audiologyneuro-otology. 14(6)
The thermo-reversible triblock copolymer poloxamer 407 was investigated as a drug delivery vehicle for micronized dexamethasone into the middle and inner ears of guinea pigs. The study characterized the gelation and in vitro release kinetics of polox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a9a57cd9c8c458324d49ca649d049e
https://pubmed.ncbi.nlm.nih.gov/19923809
https://pubmed.ncbi.nlm.nih.gov/19923809
Autor:
Katherine H. Thompson, Carl Lebel, John H. McNeill, Chris Orvig, Michael Christopher Scaife, Jay Lichter
Publikováno v:
Journal of inorganic biochemistry. 103(4)
3-Hydroxy-2-methyl-4-pyrone and 2-ethyl-3-hydroxy-4-pyrone (maltol and ethyl maltol, respectively) have proven especially suitable as ligands for vanadyl ions, in potential insulin enhancing agents for diabetes mellitus. Both bis(maltolato)oxovanadiu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76dc341b1b2b016e4fa5dd98f6b59289
https://pubmed.ncbi.nlm.nih.gov/19162329
https://pubmed.ncbi.nlm.nih.gov/19162329
Autor:
T. V. Bui, Roxana A. Radu, Gabriel H. Travis, Jay Lichter, Yun Han, Nathan L. Mata, Steven Nusinowitz, Widder Kenneth, Dean Bok
Publikováno v:
Investigative ophthalmologyvisual science. 46(12)
PURPOSE. Excessive accumulation of lipofuscin is observed in numerous degenerative retinal diseases. A toxic vitamin A- based fluorophore (A2E) present within lipofuscin has been implicated in the death of RPE and photoreceptor cells. Here, we used a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f83c0a1baa2809f6f6a2bec2e28a30
https://pubmed.ncbi.nlm.nih.gov/16303925
https://pubmed.ncbi.nlm.nih.gov/16303925