Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Jay L. Vivian"'
Autor:
Kaitlin Flannagan, Julia A. Stopperan, Brittany M. Hauger, Benjamin R. Troutwine, Colton R. Lysaker, Taylor A. Strope, Vivien Csikos Drummond, Caleb A. Gilmore, Natalie A. Swerdlow, Julia M. Draper, Cynthia M. Gouvion, Jay L. Vivian, Mohammad Haeri, Russell H. Swerdlow, Heather M. Wilkins
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
IntroductionMitochondrial dysfunction is observed in Alzheimer’s disease (AD). Altered mitochondrial respiration, cytochrome oxidase (COX) Vmax, and mitophagy are observed in human subjects and animal models of AD. Models derived from induced pluri
Externí odkaz:
https://doaj.org/article/127198d0d9af4585a86ea509bb550673
Autor:
Prashanth Anamthathmakula, Philemon D. Shallie, Neha Nayak, Sabita Dhal, Jay L. Vivian, Gil Mor, Michael J. Soares, Nihar R. Nayak
Publikováno v:
Cells, Vol 12, Iss 16, p 2096 (2023)
The aromatase-Cre recombinase (Cyp19-Cre) transgenic mouse model has been extensively used for placenta-specific gene inactivation. In a pilot study, we observed unexpected phenotypes using this mouse strain, which prompted an extensive characterizat
Externí odkaz:
https://doaj.org/article/23884fd26a6147faa481f3144cb710c8
Publikováno v:
Cell Transplantation, Vol 31 (2022)
Kernicterus is a permanent condition caused by brain damage from bilirubin toxicity. Dystonia is one of the most debilitating symptoms of kernicterus and results from damage to the globus pallidus (GP). One potential therapeutic strategy to treat dys
Externí odkaz:
https://doaj.org/article/43d5df8512ed4882b665d5b033d8a2c0
Autor:
Shaon Borosha, Anamika Ratri, Subhra Ghosh, Carrie A. Malcom, V. Praveen Chakravarthi, Jay L. Vivian, Timothy A. Fields, M. A. Karim Rumi, Patrick E. Fields
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
DOT1L is essential for embryonic hematopoiesis but the precise mechanisms of its action remain unclear. The only recognized function of DOT1L is histone H3 lysine 79 (H3K79) methylation, which has been implicated in both transcriptional activation an
Externí odkaz:
https://doaj.org/article/be4fab63f07f4ab69b19247dbc09b713
Autor:
Carrie A. Malcom, Anamika Ratri, Joanna Piasecka-Srader, Shaon Borosha, V. Praveen Chakravarthi, Nehemiah S. Alvarez, Jay L. Vivian, Timothy A. Fields, M.A. Karim Rumi, Patrick E. Fields
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
DOT1-like (DOT1L) histone methyltransferase is essential for mammalian erythropoiesis. Loss of DOT1L in knockout (Dot1l-KO) mouse embryos resulted in lethal anemia at midgestational age. The only recognized molecular function of DOT1L is its methylat
Externí odkaz:
https://doaj.org/article/9d02827bb57c496bb59d86a36e15f936
Autor:
Yi Feng, Shaon Borosha, Anamika Ratri, Eun Bee Lee, Huizhen Wang, Timothy A. Fields, William H. Kinsey, Jay L. Vivian, M. A. Karim Rumi, Patrick E. Fields
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 5137 (2022)
Erythropoietin (EPO) signaling plays a vital role in erythropoiesis by regulating proliferation and lineage-specific differentiation of murine hematopoietic progenitor cells (HPCs). An important downstream response of EPO signaling is calcium (Ca2+)
Externí odkaz:
https://doaj.org/article/0f4f3a6af3044f59aaa1f9dae9fa31ed
Autor:
Stephen C. Parnell, Archana Raman, Yan Zhang, Emily A. Daniel, Yuqiao Dai, Aditi Khanna, Gail A. Reif, Jay L. Vivian, Timothy A. Fields, Darren P. Wallace
Publikováno v:
Kidney International. 102:1103-1114
Polycystic kidney disease (PKD) is characterized by the formation and progressive enlargement of fluid-filled cysts due to abnormal cell proliferation. Cyclic AMP agonists, including arginine vasopressin, stimulate ERK-dependent proliferation of cyst
Publikováno v:
Cancer Systems and Integrative Biology ISBN: 9781071631621
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::888e76fc1f338bd00199b09a3e8d0adf
https://doi.org/10.1007/978-1-0716-3163-8_4
https://doi.org/10.1007/978-1-0716-3163-8_4
Autor:
Fu-Chen Yang, Julia Draper, Peter G. Smith, Jay L. Vivian, Steven M. Shapiro, John A. Stanford
Publikováno v:
Cell Transplantation, Vol 27 (2018)
Neonatal hyperbilirubinemia targets specific brain regions and can lead to kernicterus. One of the most debilitating symptoms of kernicterus is dystonia, which results from bilirubin toxicity to the globus pallidus (GP). Stem cell transplantation int
Externí odkaz:
https://doaj.org/article/a16e0d091e9e488a9de2115b25ec5e93
Autor:
Fu-Chen Yang, Sean M. Riordan, Michelle Winter, Li Gan, Peter G. Smith, Jay L. Vivian, Steven M. Shapiro, John A. Stanford Ph.D.
Publikováno v:
Cell Transplantation, Vol 26 (2017)
High levels of bilirubin in infants can cause kernicterus, which includes basal ganglia damage and dystonia. Stem cell transplantation may be an effective treatment for this disease. In this study, we transplanted human neural progenitor cells differ
Externí odkaz:
https://doaj.org/article/548ce0427a28492b9adbf90a3d5a8fa5