Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jay Hou"'
Autor:
Mathieu Nonnenmacher, Wei Wang, Matthew A. Child, Xiao-Qin Ren, Carol Huang, Amy Zhen Ren, Jenna Tocci, Qingmin Chen, Kelsey Bittner, Katherine Tyson, Nilesh Pande, Charlotte Hiu-Yan Chung, Steven M. Paul, Jay Hou
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss , Pp 366-378 (2021)
Therapeutic payload delivery to the central nervous system (CNS) remains a major challenge in gene therapy. Recent studies using function-driven evolution of adeno-associated virus (AAV) vectors have successfully identified engineered capsids with im
Externí odkaz:
https://doaj.org/article/fa7202f054c14b0abb47979c4151abb9
Autor:
Aleksi Isomursu, Keun-Young Park, Jay Hou, Bo Cheng, Mathilde Mathieu, Ghaidan A. Shamsan, Benjamin Fuller, Jesse Kasim, M. Mohsen Mahmoodi, Tian Jian Lu, Guy M. Genin, Feng Xu, Min Lin, Mark D. Distefano, Johanna Ivaska, David J. Odde
Publikováno v:
Nature Materials. 21:1081-1090
How cells sense tissue stiffness to guide cell migration is a fundamental question in development, fibrosis and cancer. Although durotaxis-cell migration towards increasing substrate stiffness-is well established, it remains unknown whether individua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6fe41b02974a27979a00d3bd651c2a5
https://doi.org/10.1038/s41563-022-01294-2
https://doi.org/10.1038/s41563-022-01294-2
Autor:
Pengcheng Zhou, Wang Xin, Jeffrey S. Thompson, Jay Hou, Wei Wang, Lisa M. Stanek, Adrian Philip Kells, Fen Chen, Xiao-Qin Ren, Carter Todd, Dinah W.Y. Sah, Emily Christensen
Publikováno v:
Human Gene Therapy. 33:37-60
Huntington's Disease is a fatal neurodegenerative disorder caused by an inherited mutation in the huntingtin gene (HTT) comprising an expanded cytosine-adenine-guanine (CAG) trinucleotide repeat sequence that results in a pathogenic huntingtin protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::647d671ce8166d32be7050f3df122062
https://doi.org/10.1089/hum.2021.221
https://doi.org/10.1089/hum.2021.221
Glioblastoma is the most aggressive malignant brain tumor with poor survival due to its invasive nature driven by cell migration, with unclear linkage to transcriptomic information. Here, we applied a physics-based motor-clutch model, a cell migratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a71746e5f45b9c02f92f574fe328d4b
https://doi.org/10.1101/2023.02.24.529880
https://doi.org/10.1101/2023.02.24.529880
Autor:
Wencheng Liu, Vinodh Kurella, Li Liu, Dillon Kavanagh, Maneesha Paranjpe, Jerrah Holth, Charlotte Chung, Alex Powers, Xiao‐Qin Ren, Yanqun Shu, Allen Capili, Jay Hou, Bernardino Francesco Ghetti, Kelly R. Bales, Steven M. Paul, Todd Carter
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::781775f837964c9b9968c79c8b65a321
https://doi.org/10.1002/alz.062878
https://doi.org/10.1002/alz.062878
Autor:
Wencheng Liu, Maneesha Paranjpe, Jerrah Holth, Blaise Clarke, Jeffery Thompson, Joe Clement, Elisabeth Knoll, Charlotte Chung, Adewale Adeluyi, Alex Powers, Vinodh Kurella, Dillon Kavanagh, Brian Ezell, Timothy Fiore, Kyle Grant, Jay Hou, Kelly R. Bales, Steven M. Paul, Todd Carter
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b87f0006149b9d3bce8f02e594fc040
https://doi.org/10.1002/alz.062924
https://doi.org/10.1002/alz.062924
Autor:
Wencheng Liu, Jerrah Holth, Maneesha Paranjpe, Xiao‐Qin Ren, Yanqun Shu, Giridhar Murlidharan, Charlotte Chung, Alex Powers, Emalee Peterson, Abigail Ecker, Usman Hameedi, Kyle Grant, Vinodh Kurella, Dillon Kavanagh, Omar Khwaja, Jay Hou, Steven M. Paul, Kelly R. Bales, Todd Carter
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8030993a1110767211d304cd8d6a007
https://doi.org/10.1002/alz.053341
https://doi.org/10.1002/alz.053341
Autor:
Wei, Wang, Pengcheng, Zhou, Xin, Wang, Fen, Chen, Emily, Christensen, Jeffrey, Thompson, Xiaoqin, Ren, Adrian, Kells, Lisa, Stanek, Todd, Carter, Jay, Hou, Dinah W Y, Sah
Publikováno v:
Human gene therapy. 33(1-2)
Huntington's disease is a fatal neurodegenerative disorder caused by an inherited mutation in the huntingtin (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bac0214cc396af1a443cbabb55c80d70
https://pubmed.ncbi.nlm.nih.gov/34806402
https://pubmed.ncbi.nlm.nih.gov/34806402
Autor:
Tian Jian Lu, Feng Xu, Cheng Bo, Ghaidan Shamsan, David J. Odde, Guy M. Genin, Jay Hou, Johanna Ivaska, Mark D. Distefano, Min Lin, Aleksi Isomursu, Keun-Young Park, M. Mohsen Mahmoodi, Jesse A. Kasim, Benjamin J. Fuller
Durotaxis – the ability of cells to sense and migrate along stiffness gradients – is important for embryonic development and has been implicated in pathologies including fibrosis and cancer. Although cellular processes can sometimes turn toward s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fbb8ccbc99296bb1de7f255981456f5
https://doi.org/10.1101/2020.10.27.357178
https://doi.org/10.1101/2020.10.27.357178
Autor:
Steve Weber, Kelly Tenneson, Eric Furfine, Gary Wolfe, Elizabeth Hopkins, Jay Hou, Joseph Kovalchin, Allyson Masci, Christian Li, Kathy Collins, Bracken M. King, Jeremy Fry
Publikováno v:
Eyecontact lens. 44(3)
Objective Topical interleukin (IL)-1 receptor (R)1 blockade is therapeutically active in reducing signs and symptoms of dry eye disease. Herein, we describe in vitro and in vivo nonclinical Investigational New Drug (IND)-enabling studies of EBI-005,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7bfb22275cbdbb4aaa6ebe898b11224
https://pubmed.ncbi.nlm.nih.gov/28727604
https://pubmed.ncbi.nlm.nih.gov/28727604