Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Jay F. Larrow"'
Autor:
Rachel C. Epplin, Shashwati Paul, Loïc Herter, Christophe Salome, Erin N. Hancock, Jay F. Larrow, Erich W. Baum, David R. Dunstan, Carol Ginsburg-Moraff, Thomas C. Fessard, M. Kevin Brown
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-5 (2022)
The development of new classes of isosteres and building blocks is crucial to the advancement of medicinal chemistry programs. Here, the authors report the synthesis and development of ladderanes to act as replacements for meta-substituted aromatic r
Externí odkaz:
https://doaj.org/article/ebd0a84e99d044029fceee6ab73bf297
Autor:
Jay F. Larrow, Eric N. Jacobsen
Publikováno v:
Organometallics in Process Chemistry ISBN: 9783540016038
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f886adfa24cac336236b50041143052
https://doi.org/10.1007/b11772
https://doi.org/10.1007/b11772
Autor:
Alessandro A, Boezio, Loren, Berry, Brian K, Albrecht, David, Bauer, Steven F, Bellon, Christiane, Bode, April, Chen, Deborah, Choquette, Isabelle, Dussault, Mei, Fang, Satoko, Hirai, Paula, Kaplan-Lefko, Jay F, Larrow, Min-Hwa Jasmine, Lin, Julia, Lohman, Michele H, Potashman, Yusheng, Qu, Karen, Rex, Michael, Santostefano, Kavita, Shah, Roman, Shimanovich, Stephanie K, Springer, Yohannes, Teffera, Yajing, Yang, Yihong, Zhang, Jean-Christophe, Harmange
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:6307-6312
Deregulation of the receptor tyrosine kinase c-Met has been implicated in several human cancers and is an attractive target for small molecule drug discovery. We previously showed that O-linked triazolopyridazines can be potent inhibitors of c-Met. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0b10a5ad55ecc74d815faf7ae06e59b
https://doi.org/10.1016/j.bmcl.2009.09.096
https://doi.org/10.1016/j.bmcl.2009.09.096
Publikováno v:
Tetrahedron: Asymmetry. 14:3589-3592
The hydrolytic kinetic resolution of racemic terminal epoxides utilizing chiral (salen)Co(III) catalysts provides practical access to enantiopure epoxides and diols. However, general issues surrounding catalyst activation combined with the specific p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5e27dd569d003aee78cab34820128be
https://doi.org/10.1016/j.tetasy.2003.09.018
https://doi.org/10.1016/j.tetasy.2003.09.018
Publikováno v:
Advanced Synthesis & Catalysis. 343:5-26
This review provides a critical analysis of catalytic kinetic resolution reactions from a practical perspective, asking the question of when, if ever, is kinetic resolution the best option for the synthesis of an optically active target. A series of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dce108387ded2a57e8e8217d34d76830
https://doi.org/10.1002/1615-4169(20010129)343:1<5::aid-adsc5>3.0.co
https://doi.org/10.1002/1615-4169(20010129)343:1<5::aid-adsc5>3.0.co
Publikováno v:
Tetrahedron Letters. 38:773-776
The chiral Co(salen) complex 3 is an effective catalyst for the asymmetric ring-opening of meso epoxides with benzoic acid. Enantioselectivities of 55–93% were obtained with a range of substrates.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0892246b347e23674d7e30bdba04dd8
https://doi.org/10.1016/s0040-4039(96)02414-8
https://doi.org/10.1016/s0040-4039(96)02414-8
Publikováno v:
The Journal of Organic Chemistry. 59:1939-1942
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ea6f6e4ea01780d43e1e4229ad9e52e
https://doi.org/10.1021/jo00086a062
https://doi.org/10.1021/jo00086a062
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ff7a1df028e711863ba01ad234df4dc
https://doi.org/10.1002/chin.199436210
https://doi.org/10.1002/chin.199436210
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8418897082eb756c50ec738cbd204f41
https://doi.org/10.1002/chin.199647029
https://doi.org/10.1002/chin.199647029
Publikováno v:
ChemInform. 28
The chiral Co(salen) complex 3 is an effective catalyst for the asymmetric ring-opening of meso epoxides with benzoic acid. Enantioselectivities of 55–93% were obtained with a range of substrates.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::509fbc8a2ae18b4dd62471aec13e03b2
https://doi.org/10.1002/chin.199723101
https://doi.org/10.1002/chin.199723101