Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jay Daniels"'
Autor:
Jay Daniels, Peter G. Doukas, Maria E. Martinez Escala, Kimberly G. Ringbloom, David J. H. Shih, Jingyi Yang, Kyle Tegtmeyer, Joonhee Park, Jane J. Thomas, Mehmet E. Selli, Can Altunbulakli, Ragul Gowthaman, Samuel H. Mo, Balaji Jothishankar, David R. Pease, Barbara Pro, Farah R. Abdulla, Christopher Shea, Nidhi Sahni, Alejandro A. Gru, Brian G. Pierce, Abner Louissaint, Joan Guitart, Jaehyuk Choi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Cutaneous gamma-delta T cell lymphomas are rare but aggressive cancers. Here, by DNA, RNA and T cell receptor sequencing, the authors elucidate the molecular ontogeny by revising the cell of origin and identifying potentially targetable mutations.
Externí odkaz:
https://doaj.org/article/2c834194658843db9eea5ff1ea5e480a
Autor:
Jay Daniels, Jaehyuk Choi
Publikováno v:
Blood
We performed a phase 1 clinical trial to evaluate outcomes in patients receiving donor-derived CD19-specific chimeric antigen receptor (CAR) T cells for B-cell malignancy that relapsed or persisted after matched related allogeneic hemopoietic stem ce
Autor:
Kyle Tegtmeyer, Balaji Jothishankar, Ragul Gowthaman, Farah Abdulla, Nidhi Sahni, Samuel H. Mo, Joan Guitart, Mehmet E. Selli, David R. Pease, Peter G. Doukas, Joonhee Park, Can Altunbulakli, Jane J. Thomas, Jay Daniels, Barbara Pro, David Shih, Maria Estela Martinez Escala, Jingyi Yang, Kimberly G. Ringbloom, Christopher R. Shea, Abner Louissaint, Alejandro A. Gru, Jaehyuk Choi, Brian G. Pierce
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
Primary cutaneous γδ T cell lymphomas (PCGDTLs) represent a heterogeneous group of uncommon but aggressive cancers. Herein, we perform genome-wide DNA, RNA, and T cell receptor (TCR) sequencing on 29 cutaneous γδ lymphomas. We find that PCGDTLs a
Publikováno v:
J Vitreoretin Dis
Purpose: To describe a case with an unusual presentation of Propionibacterium acnes ( P acnes) with ultimately a good visual outcome. Methods: A case report with review of approaches to P acnes endophthalmitis. Results: We describe a patient with an
Autor:
Lei Zhao, Tony Hsiao, Connor Stonesifer, Jay Daniels, Tiffany J. Garcia-Saleem, Jaehyuk Choi, Larisa Geskin, Alain H. Rook, Gary S. Wood
Publikováno v:
Journal of Investigative Dermatology. 142:3253-3261.e4
Combined BET inhibitor/histone deacetylase inhibitor treatment induces marked apoptosis of cutaneous T-cell lymphoma (CTCL) with minimal normal T-cell toxicity. At 96 hours when apoptosis was extensive, a majority of CTCL lines showed ≥2-fold suppr
Autor:
Jeffrey A. Sosman, Tim Wartewig, Joan Guitart, Maria Estela Martinez-Escala, Joonhee Park, Jürgen Ruland, Jay Daniels, Barbara Pro, Deepak A. Rao, Jaehyuk Choi
Publikováno v:
European Journal of Cancer. 156:S2-S3
Introduction: Cutaneous T cell lymphomas (CTCLs) are a heterogenous group of lymphomas of the skin-homing CD4+ T cell. Although the median survival for patients with stage IV disease is generally poor, there is significant heterogeneity with some sta
Autor:
Alain H. Rook, Jianqiang Wu, Minakshi Nihal, Jay Daniels, Gary S. Wood, Larisa J. Geskin, Jaehyuk Choi, Connor J. Stonesifer
Publikováno v:
J Invest Dermatol
Autor:
Jane J. Thomas, Kyle Tegtmeyer, Joan Guitart, Deepak A. Rao, Tim Wartewig, Kimberly G. Ringbloom, Caroline Snowden, Pui-Yan Kwok, Calvin Law, Joonhee Park, Carly Conran, David R. Pease, Jay Daniels, Yujin Lee, Katie Lee, Jeffrey A. Sosman, Farah Abdulla, Barbara Pro, Jingyi Yang, Sara Choi, Balaji Jothishankar, Samuel H. Mo, Titus J. Boggon, Jaehyuk Choi, Maria Estela Martinez-Escala, Yancong Zhang, Jürgen Ruland, Peter G. Doukas, Abner Louissaint
Publikováno v:
Blood
Cutaneous T-cell lymphomas (CTCLs) are a clinically heterogeneous collection of lymphomas of the skin-homing T cell. To identify molecular drivers of disease phenotypes, we assembled representative samples of CTCLs from patients with diverse disease
Autor:
Jingyi Yang, Joan Guitart, Caroline Snowden, Jeffrey A. Sosman, Barbara Pro, Joonhee Park, Kimberly G. Ringbloom, Jaehyuk Choi, Samuel Mo, Maria Estela Martinez-Escala, Jay Daniels, Yancong Zhang
Publikováno v:
European Journal of Cancer. 156:S2
Autor:
Marc L. Mendillo, Joan Guitart, Akshaya Ramachandran, Titus J. Boggon, Joonhee Park, Juhyun Kim, Jaehyuk Choi, Jay Daniels, Barbara Pro, Nduka Amankulor, Estela Martinez-Escala, Jingyi Yang, Alexander Wenzel, Jeffrey N. Savas, Wung Jae Lee
Publikováno v:
Blood. 130:1430-1440
Cutaneous T-cell lymphoma (CTCL) is an incurable non-Hodgkin lymphoma of the skin-homing T cell. In early-stage disease, lesions are limited to the skin, but in later-stage disease, the tumor cells can escape into the blood, the lymph nodes, and at t