Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jay D. Naik"'
Publikováno v:
Journal of Clinical Pathology. 65:580-584
Mucinous epithelial ovarian cancers (mEOC) are a relatively rare subset of ovarian cancers. Despite a relatively favourable outcome in early disease, the more frequent advanced presentation is associated with poorer response to platinum/taxane chemot
Publikováno v:
Clinical Cancer Research. 17:4214-4224
Oncolytic viruses consist of a diverse range of DNA and RNA viruses traditionally thought to mediate their effects by exploiting aberrations in tumor pathways, allowing preferential viral replication in, and killing of, tumor cells. Clinical developm
Autor:
Jian Qiao, Jay D. Naik, John C. Bell, Hongxun Wang, K.J. Harrington, Kelley Parato, Timothy Kottke, Richard G. Vile, Candice Willmon, Andrew W. Hudacek, Jill Thompson, Rosa Maria Diaz, Alan Melcher, John D. Chester, Peter Selby
Publikováno v:
Gene Therapy. 15:604-616
Although adoptive T-cell therapy has shown clinical success, efficacy is limited by low levels of T-cell trafficking to, and survival in, the immunosuppressive environment of an established tumor. Oncolytic virotherapy has recently emerged as a promi
Autor:
Tomohisa Saito, Chris Twelves, Janet A Hartley, Donna Crawford, Masaichi Abe, Keith Jones, Iain R. Macpherson, Thomas Jeff Evans, Masanori Miwa, John M Hartley, D. Alan Anthoney, Jay D. Naik
Publikováno v:
BMC Cancer, Vol 12, Iss 1, p 536 (2012)
BMC Cancer
BMC Cancer
Background A Phase I dose escalation first in man study assessed maximum tolerated dose (MTD), dose-limiting toxicity (DLT) and recommended Phase II dose of TP300, a water soluble prodrug of the Topo-1 inhibitor TP3076, and active metabolite, TP3011.
Autor:
Christopher Bradley, S Michael Crawford, Julia Brown, Ivo M. Hennig, David Alan Anthoney, Alex J Szubert, Alan M. Melcher, Jay D. Naik, Matthew T. Seymour, David A. Jackson, Sarah Brown
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 26(20)
Purpose Options for single-agent fluoropyrimidine adjuvant therapy after bowel cancer resection include intravenous fluorouracil with leucovorin (FU/LV) or oral capecitabine. These treatments have similar efficacy but differ in convenience and toxici
Autor:
Johnathan Joffe, John D. Chester, Loaie M. El-Helw, Robert E. Coleman, Peter Selby, Jay D. Naik
Publikováno v:
BJU international. 98(3)
OBJECTIVE: To report our experience of high-dose chemotherapy (HDC) with haematopoietic stem-cell support (HSC) in patients with poor risk, relapsed or refractory germ cell tumours (GCTs), as this treatment might offer effective salvage for patients
Publikováno v:
Journal of Clinical Pathology; Jul2012, Vol. 65 Issue 7, p580-584, 5p