Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Jay Cao"'
Autor:
Yuanzhen Peng, Solomon Langermann, Priyanka Kothari, Linda Liu, Wei Zhao, Yizhong Hu, Zihao Chen, Mariana Moraes de Lima Perini, Jiliang Li, Jay Cao, X. Edward Guo, Lieping Chen, William A. Bauman, Weiping Qin
Publikováno v:
JBMR Plus, Vol 7, Iss 12, Pp n/a-n/a (2023)
ABSTRACT Rapid and extensive sublesional bone loss after spinal cord injury (SCI) is a difficult medical problem that has been refractory to available interventions except the antiresorptive agent denosumab (DMAB). While DMAB has shown some efficacy
Externí odkaz:
https://doaj.org/article/6c5438c0c2fa41ba8b85c1bb24c33ffb
Publikováno v:
Frontiers in Artificial Intelligence, Vol 6 (2023)
We show how reinforcement learning can be used in conjunction with quantile regression to develop a hedging strategy for a trader responsible for derivatives that arrive stochastically and depend on a single underlying asset. We assume that the trade
Externí odkaz:
https://doaj.org/article/e6ec3324d6994697b2efba26803914cb
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Primary cilia are highly conserved microtubule-based organelles that play essential roles in several cellular processes including osteogenesis. Here the authors show that intraflagellar protein IFT80 regulates osteoblast differentiation by balancing
Externí odkaz:
https://doaj.org/article/fa47de65a8d94f02b609829c08f8d26e
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35492 (2012)
CCAAT/enhancer binding protein γ (C/EBPγ) is a member of the C/EBP family of transcription factors, which lacks known activation domains. C/EBPγ was originally described as an inhibitor of C/EBP transactivation potential. However, previous study d
Externí odkaz:
https://doaj.org/article/37db6552f9f4497b80f37e75f2b61dd9
Autor:
Ling-Ling Zhu, Jay Cao, Merry Sun, Tony Yuen, Raymond Zhou, Jianhua Li, Yuanzhen Peng, Surinder S Moonga, Lida Guo, Jeffrey I Mechanick, Jameel Iqbal, Liu Peng, Harry C Blair, Zhuan Bian, Mone Zaidi
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47058 (2012)
Epidemiologic studies correlate low vitamin C intake with bone loss. The genetic deletion of enzymes involved in de novo vitamin C synthesis in mice, likewise, causes severe osteoporosis. However, very few studies have evaluated a protective role of
Externí odkaz:
https://doaj.org/article/a01bbb06578c4d37ba9067dcb4e230fb
Autor:
Jay Cao1 jay.cao@rotman.utoron.ca, Jacky Chen2 jackyjc.chen@rotman.utoronto.ca, Hull, John3 john.hull@rotman.utoronto.ca, Poulos, Zissis4 zissis.poulos@rotman.utoronto.ca
Publikováno v:
Journal of Financial Data Science. Winter2022, Vol. 4 Issue 1, p41-53. 13p.
Publikováno v:
The Quarterly Journal of Finance. 13
Delta-hedged option returns consistently decrease in volatility of volatility changes (volatility uncertainty), for both implied and realized volatilities. We provide a thorough investigation of the underlying mechanisms including model-risk and gamb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1105f50a15d3cea38be88025429f3376
https://doi.org/10.1142/s2010139223500052
https://doi.org/10.1142/s2010139223500052
Publikováno v:
The Journal of Financial Data Science. 3:10-27
This paper shows how reinforcement learning can be used to derive optimal hedging strategies for derivatives when there are transaction costs. The paper illustrates the approach by showing the difference between using delta hedging and optimal hedgin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7449344d7b91ff14f8dce71e087f29
https://doi.org/10.3905/jfds.2020.1.052
https://doi.org/10.3905/jfds.2020.1.052
Autor:
Guodong Pan, Meghan E McGee Lawrence, Jianru Xu, Hongyan Zhou, Yonggang Bao, Jay Cao, Mark W. Hamrick, Xingming Shi, Kehong Ding, Carlos M Isales, Raysa Rosario, Yun Su
Publikováno v:
J Gerontol A Biol Sci Med Sci
Bone loss in aging is linked with chronic low-grade inflammation and the accumulation of marrowfat in animals and humans. Peroxisome proliferator-activated receptor gamma (PPARγ), an adipogenic regulator, plays key roles in these biological processe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e7e1406e63ead59ae995257cf28af37
https://doi.org/10.1093/gerona/glaa049
https://doi.org/10.1093/gerona/glaa049
Publikováno v:
Curr Dev Nutr
OBJECTIVES: Obesity is detrimental to bone health in humans and in high-fat diet-induced obese animals. Bone marrow osteoblasts and adipocytes are derived from a common mesenchymal stem cell and have a reciprocal relationship. Peroxisome proliferator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c2a5660d1b7cc488c0d9bc723a2c10
https://europepmc.org/articles/PMC8180769/
https://europepmc.org/articles/PMC8180769/
