Zobrazeno 1 - 10
of 715
pro vyhledávání: '"Jay A. Tischfield"'
Autor:
Sheng Wang, Belinda Wang, Vanessa Drury, Sam Drake, Nawei Sun, Hasan Alkhairo, Juan Arbelaez, Clif Duhn, Tourette International Collaborative Genetics (TIC Genetics), Vanessa H. Bal, Kate Langley, Joanna Martin, Pieter J. Hoekstra, Andrea Dietrich, Jinchuan Xing, Gary A. Heiman, Jay A. Tischfield, Thomas V. Fernandez, Michael J. Owen, Michael C. O’Donovan, Anita Thapar, Matthew W. State, A. Jeremy Willsey
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Autism spectrum disorder (ASD), Tourette syndrome (TS), and attention-deficit/hyperactivity disorder (ADHD) display strong male sex bias, due to a combination of genetic and biological factors, as well as selective ascertainment. While the h
Externí odkaz:
https://doaj.org/article/0f0d828cb9a44cc7a0dc9536fdc3e9b0
Autor:
Fotis Tsetsos, Dongmei Yu, Jae Hoon Sul, Alden Y. Huang, Cornelia Illmann, Lisa Osiecki, Sabrina M. Darrow, Matthew E. Hirschtritt, Erica Greenberg, Kirsten R. Muller-Vahl, Manfred Stuhrmann, Yves Dion, Guy A. Rouleau, Harald Aschauer, Mara Stamenkovic, Monika Schlögelhofer, Paul Sandor, Cathy L. Barr, Marco A. Grados, Harvey S. Singer, Markus M. Nöthen, Johannes Hebebrand, Anke Hinney, Robert A. King, Thomas V. Fernandez, Csaba Barta, Zsanett Tarnok, Peter Nagy, Christel Depienne, Yulia Worbe, Andreas Hartmann, Cathy L. Budman, Renata Rizzo, Gholson J. Lyon, William M. McMahon, James R. Batterson, Danielle C. Cath, Irene A. Malaty, Michael S. Okun, Cheston Berlin, Douglas W. Woods, Paul C. Lee, Joseph Jankovic, Mary M. Robertson, Donald L. Gilbert, Lawrence W. Brown, Barbara J. Coffey, Andrea Dietrich, Pieter J. Hoekstra, Samuel Kuperman, Samuel H. Zinner, Michael Wagner, James A. Knowles, A. Jeremy Willsey, Jay A. Tischfield, Gary A. Heiman, Nancy J. Cox, Nelson B. Freimer, Benjamin M. Neale, Lea K. Davis, Giovanni Coppola, Carol A. Mathews, Jeremiah M. Scharf, Peristera Paschou, on behalf of the Tourette Association of America International Consortium for Genetics, Sabrina Darrow, Roger Kurlan, James F. Leckman, Jan H. Smit, the Gilles de la Tourette GWAS Replication Initiative, Harald Aschauer Harald Aschauer, Anastasios Konstantinidis, Kirsten Müller-Vahl, Tomasz Wolanczyk, the Tourette International Collaborative Genetics Study, Lawrence Brown, Keun-Ah Cheon, Blanca Garcia-Delgar, Donald Gilbert, Dorothy E. Grice, Julie Hagstrøm, Tammy Hedderly, Isobel Heyman, Chaim Huyser, Young Key Kim, Young-Shin Kim, Yun-Joo Koh, Sodahm Kook, Bennett L. Leventhal, Marcos Madruga-Garrido, Pablo Mir, Astrid Morer, Alexander Münchau, Kerstin J. Plessen, Veit Roessner, Eun-Young Shin, Dong-Ho Song, Jungeun Song, Samuel Zinner, and the Psychiatric Genomics Consortium Tourette Syndrome Working Group, Thomas Fernandez, Gary Heiman, Pieter Hoekstra, Jay Tischfield, Douglas Woods
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Tourette syndrome (TS) is a neuropsychiatric disorder of complex genetic architecture involving multiple interacting genes. Here, we sought to elucidate the pathways that underlie the neurobiology of the disorder through genome-wide analysis
Externí odkaz:
https://doaj.org/article/1e03ee514141459ab171b2316307b113
Autor:
Lauren E. Woodard, Richard C. Welch, Ruth Ann Veach, Thomas M. Beckermann, Feng Sha, Edward J. Weinman, Talat Alp Ikizler, Jay A. Tischfield, Amrik Sahota, Matthew H. Wilson
Publikováno v:
BMC Nephrology, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background Cystinuria is an inherited disorder of renal amino acid transport that causes recurrent nephrolithiasis and significant morbidity in humans. It has an incidence of 1 in 7000 worldwide making it one of the most common genetic disor
Externí odkaz:
https://doaj.org/article/34f494f6358f467691d7f610d71a6800
Autor:
Sheng Wang, Jeffrey D. Mandell, Yogesh Kumar, Nawei Sun, Montana T. Morris, Juan Arbelaez, Cara Nasello, Shan Dong, Clif Duhn, Xin Zhao, Zhiyu Yang, Shanmukha S. Padmanabhuni, Dongmei Yu, Robert A. King, Andrea Dietrich, Najah Khalifa, Niklas Dahl, Alden Y. Huang, Benjamin M. Neale, Giovanni Coppola, Carol A. Mathews, Jeremiah M. Scharf, Thomas V. Fernandez, Joseph D. Buxbaum, Silvia De Rubeis, Dorothy E. Grice, Jinchuan Xing, Gary A. Heiman, Jay A. Tischfield, Peristera Paschou, A. Jeremy Willsey, Matthew W. State
Publikováno v:
Cell Reports, Vol 24, Iss 13, Pp 3441-3454.e12 (2018)
Summary: We previously established the contribution of de novo damaging sequence variants to Tourette disorder (TD) through whole-exome sequencing of 511 trios. Here, we sequence an additional 291 TD trios and analyze the combined set of 802 trios. W
Externí odkaz:
https://doaj.org/article/49c5d49b10be47ef8ef174ef17388b73
Autor:
Heather McGowan, Vincent R. Mirabella, Aula Hamod, Aziz Karakhanyan, Nicole Mlynaryk, Jennifer C. Moore, Jay A. Tischfield, Ronald P. Hart, Zhiping P. Pang
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 10 (2018)
Non-coding RNA, including microRNA (miRNA) serves critical regulatory functions in the developing brain. The let-7 family of miRNAs has been shown to regulate neuronal differentiation, neural subtype specification, and synapse formation in animal mod
Externí odkaz:
https://doaj.org/article/76ab7ffd7940456480c2b11fdad298d2
Autor:
Iya Prytkova, Yiyuan Liu, Michael Fernando, Isabel Gameiro-Ros, Dina Popova, Chella Kamarajan, Xiaoling Xuei, David B. Chorlian, Howard J. Edenberg, Jay A. Tischfield, Bernice Porjesz, Zhiping P. Pang, Ronald P. Hart, Alison Goate, Paul A. Slesinger
Publikováno v:
bioRxiv
SUMMARYGenome-wide association analysis of electroencephalographic endophenotypes for alcohol use disorder has identified non-coding polymorphisms within theKCNJ6gene.KCNJ6encodes the GIRK2 protein, a subunit of a G-protein-coupled inwardly-rectifyin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e14fcd5e6cb7ed030584e557640734
https://europepmc.org/articles/PMC10055374/
https://europepmc.org/articles/PMC10055374/
Autor:
Fotis Tsetsos, Apostolia Topaloudi, Pritesh Jain, Zhiyu Yang, Dongmei Yu, Petros Kolovos, Zeynep Tumer, Renata Rizzo, Andreas Hartmann, Christel Depienne, Yulia Worbe, Kirsten R. Müller-Vahl, Danielle C. Cath, Dorret I. Boomsma, Tomasz Wolanczyk, Cezary Zekanowski, Csaba Barta, Zsofia Nemoda, Zsanett Tarnok, Shanmukha S. Padmanabhuni, Joseph D. Buxbaum, Dorothy Grice, Jeffrey Glennon, Hreinn Stefansson, Bastian Hengerer, Evangelia Yannaki, John A. Stamatoyannopoulos, Noa Benaroya-Milshtein, Francesco Cardona, Tammy Hedderly, Isobel Heyman, Chaim Huyser, Pablo Mir, Astrid Morer, Norbert Mueller, Alexander Munchau, Kerstin J. Plessen, Cesare Porcelli, Veit Roessner, Susanne Walitza, Anette Schrag, Davide Martino, Jay A. Tischfield, Gary A. Heiman, A. Jeremy Willsey, Andrea Dietrich, Lea K. Davis, James J. Crowley, Carol A. Mathews, Jeremiah M. Scharf, Marianthi Georgitsi, Pieter J. Hoekstra, Peristera Paschou, Cathy L. Barr, James R. Batterson, Cheston Berlin, Cathy L. Budman, Giovanni Coppola, Nancy J. Cox, Sabrina Darrow, Yves Dion, Nelson B. Freimer, Marco A. Grados, Erica Greenberg, Matthew E. Hirschtritt, Alden Y. Huang, Cornelia Illmann, Robert A. King, Roger Kurlan, James F. Leckman, Gholson J. Lyon, Irene A. Malaty, William M. McMahon, Benjamin M. Neale, Michael S. Okun, Lisa Osiecki, Mary M. Robertson, Guy A. Rouleau, Paul Sandor, Harvey S. Singer, Jan H. Smit, Jae Hoon Sul, Christos Androutsos, Entela Basha, Luca Farkas, Jakub Fichna, Piotr Janik, Mira Kapisyzi, Iordanis Karagiannidis, Anastasia Koumoula, Peter Nagy, Joanna Puchala, Natalia Szejko, Urszula Szymanska, Vaia Tsironi, Alan Apter, Juliane Ball, Benjamin Bodmer, Emese Bognar, Judith Buse, Marta Correa Vela, Carolin Fremer, Blanca Garcia-Delgar, Mariangela Gulisano, Annelieke Hagen, Julie Hagstrøm, Marcos Madruga-Garrido, Alessandra Pellico, Daphna Ruhrman, Jaana Schnell, Paola Rosaria Silvestri, Liselotte Skov, Tamar Steinberg, Friederike Tagwerker Gloor, Victoria L. Turner, Elif Weidinger, John Alexander, Tamas Aranyi, Wim R. Buisman, Jan K. Buitelaar, Nicole Driessen, Petros Drineas, Siyan Fan, Natalie J. Forde, Sarah Gerasch, Odile A. van den Heuvel, Cathrine Jespersgaard, Ahmad S. Kanaan, Harald E. Möller, Muhammad S. Nawaz, Ester Nespoli, Luca Pagliaroli, Geert Poelmans, Petra J.W. Pouwels, Francesca Rizzo, Dick J. Veltman, Ysbrand D. van der Werf, Joanna Widomska, Nuno R. Zilhäo, Lawrence W. Brown, Keun-Ah Cheon, Barbara J. Coffey, Thomas V. Fernandez, Donald L. Gilbert, Hyun Ju Hong, Laura Ibanez-Gomez, Eun-Joo Kim, Young Key Kim, Young-Shin Kim, Yun-Joo Koh, Sodahm Kook, Samuel Kuperman, Bennett L. Leventhal, Athanasios Maras, Tara L. Murphy, Eun-Young Shin, Dong-Ho Song, Jungeun Song, Matthew W. State, Frank Visscher, Sheng Wang, Samuel H. Zinner
Publikováno v:
Biological Psychiatry. Elsevier USA
Biological psychiatry. Elsevier USA
The TSAICG, The TIC Genetics Collaborative Group, The TSGeneSEE Initiative, The EMTICS Collaborative Group, The TS-EUROTRAIN Network & The PGC TS Working Group 2023, ' Genome-wide Association Study Points to Novel Locus for Gilles de la Tourette Syndrome ', Biological Psychiatry . https://doi.org/10.1016/j.biopsych.2023.01.023
Tsetsos, F, Topaloudi, A, Jain, P, Cath, D C, Boomsma, D I, Georgitsi, M, Hoekstra, P J, Paschou, P & Tourette Syndrome Association International Consortium for Genetics (TSAICG) 2023, ' Genome-wide Association Study points to novel locus for Gilles de la Tourette Syndrome ', Biological psychiatry . https://doi.org/10.1016/j.biopsych.2023.01.023
Biological psychiatry. Elsevier USA
The TSAICG, The TIC Genetics Collaborative Group, The TSGeneSEE Initiative, The EMTICS Collaborative Group, The TS-EUROTRAIN Network & The PGC TS Working Group 2023, ' Genome-wide Association Study Points to Novel Locus for Gilles de la Tourette Syndrome ', Biological Psychiatry . https://doi.org/10.1016/j.biopsych.2023.01.023
Tsetsos, F, Topaloudi, A, Jain, P, Cath, D C, Boomsma, D I, Georgitsi, M, Hoekstra, P J, Paschou, P & Tourette Syndrome Association International Consortium for Genetics (TSAICG) 2023, ' Genome-wide Association Study points to novel locus for Gilles de la Tourette Syndrome ', Biological psychiatry . https://doi.org/10.1016/j.biopsych.2023.01.023
Background: Tourette syndrome (TS) is a childhood-onset neurodevelopmental disorder of complex genetic architecture and is characterized by multiple motor tics and at least one vocal tic persisting for more than 1 year. Methods: We performed a genome
Autor:
Frank Visscher, Kerstin J. Plessen, Tammy Hedderly, Jungeun Song, Bennett L. Leventhal, Eun-Young Shin, Lawrence W. Brown, Alexander Münchau, Robert A. King, Young Key Kim, Young Shin Kim, Veit Roessner, Andrea Dietrich, Samuel Kuperman, Thomas V. Fernandez, Keun-Ah Cheon, Carol A. Mathews, Athanasios Maras, Donald L. Gilbert, Yun-Joo Koh, Laura Ibanez-Gomez, Dongmei Yu, Astrid Morer, Sodahm Kook, Marcos Madruga-Garrido, Julie Hagstrøm, Dorothy E. Grice, Jay A. Tischfield, Lisa Osiecki, Mohamed Abdulkadir, Blanca Garcia-Delgar, Samuel H. Zinner, Chaim Huyser, Barbara J. Coffey, Dong-Ho Song, Gary A. Heiman, Pieter J. Hoekstra, Hyun Ju Hong, Pablo Mir, Isobel Heyman, Jeremiah M. Scharf
Publikováno v:
Journal of neural transmission (Vienna, Austria : 1996), vol 128, iss 11
Journal of Neural Transmission
Journal of Neural Transmission, 128, 1757-1765. SPRINGER WIEN
Digital.CSIC. Repositorio Institucional del CSIC
instname
Journal of neural transmission (Vienna, Austria, 128(11), 1757-1765. Springer Verlag
Abdulkadir, M, Yu, D, Osiecki, L, King, R A, Fernandez, T V, Brown, L W, Cheon, K A, Coffey, B J, Garcia-Delgar, B, Gilbert, D L, Grice, D E, Hagstrøm, J, Hedderly, T, Heyman, I, Hong, H J, Huyser, C, Ibanez-Gomez, L, Kim, Y K, Kim, Y S, Koh, Y J, Kook, S, Kuperman, S, Leventhal, B, Madruga-Garrido, M, Maras, A, Mir, P, Morer, A, Münchau, A, Plessen, K J, Roessner, V, Shin, E Y, Song, D H, Song, J, Visscher, F, Zinner, S H, Mathews, C A, Scharf, J M, Tischfield, J A, Heiman, G A, Dietrich, A & Hoekstra, P J 2021, ' Investigation of gene–environment interactions in relation to tic severity ', Journal of Neural Transmission, vol. 128, no. 11, pp. 1757-1765 . https://doi.org/10.1007/s00702-021-02396-y
Journal of neural transmission, vol. 128, no. 11, pp. 1757-1765
Journal of Neural Transmission
Journal of Neural Transmission, 128, 1757-1765. SPRINGER WIEN
Digital.CSIC. Repositorio Institucional del CSIC
instname
Journal of neural transmission (Vienna, Austria, 128(11), 1757-1765. Springer Verlag
Abdulkadir, M, Yu, D, Osiecki, L, King, R A, Fernandez, T V, Brown, L W, Cheon, K A, Coffey, B J, Garcia-Delgar, B, Gilbert, D L, Grice, D E, Hagstrøm, J, Hedderly, T, Heyman, I, Hong, H J, Huyser, C, Ibanez-Gomez, L, Kim, Y K, Kim, Y S, Koh, Y J, Kook, S, Kuperman, S, Leventhal, B, Madruga-Garrido, M, Maras, A, Mir, P, Morer, A, Münchau, A, Plessen, K J, Roessner, V, Shin, E Y, Song, D H, Song, J, Visscher, F, Zinner, S H, Mathews, C A, Scharf, J M, Tischfield, J A, Heiman, G A, Dietrich, A & Hoekstra, P J 2021, ' Investigation of gene–environment interactions in relation to tic severity ', Journal of Neural Transmission, vol. 128, no. 11, pp. 1757-1765 . https://doi.org/10.1007/s00702-021-02396-y
Journal of neural transmission, vol. 128, no. 11, pp. 1757-1765
Tourette syndrome (TS) is a neuropsychiatric disorder with involvement of genetic and environmental factors. We investigated genetic loci previously implicated in Tourette syndrome and associated disorders in interaction with pre- and perinatal adver
Autor:
Charlotte Labrie-Cleary, Jitendra Singh, Steven Arnold, Andrew Sam, Mark Dresel, Luz Helena Alfaro Alvarado, Rebecca Roberts, Emily Fingar, Jennifer Jiang, Paul Craig, Jean Baum, Eddy Arnold, Christine Zardecki, Grace Brannigan, Julia R. Koeppe, Elizabeth M Hennen, Alan Trudeau, Joseph H Lubin, Thejasvi Venkatachalam, Jonathan K. Williams, Kevin Catalfano, Stephen K. Burley, Brian P. Hudson, Isaac Paredes, Sagar D. Khare, Yana Bromberg, Katherine See, Evan Lenkeit, Shuchismita Dutta, J. Steen Hoyer, Erika McCarthy, Michael J. Pikaart, Santiago Soto Zapata, Jenna Currier, Stephanie Laporte, Jay A. Tischfield, Siobain Duffy, Britney Dyszel, Maria Voigt, Changpeng Lu, Bonnie L. Hall, Jesse Sandberg, Kailey Martin, Aaliyah Khan, Stephen A. Mills, Sophia Staggers, Allison Rupert, Elliott M Dolan, Vidur Sarma, Lindsey Whitmore, Helen Zheng, Ashish Duvvuru, David S. Goodsell, Michael Kirsch, Melanie Ortiz-Alvarez de la Campa, Ali A Khan, Matthew Benedek, Francesc X. Ruiz, John D. Westbrook, Marilyn Orellana, Lingjun Xie, Zhuofan Shen, Baleigh Wheeler, Brea Tinsley
Publikováno v:
Proteins
bioRxiv
bioRxiv
Three-dimensional structures of SARS-CoV-2 and other coronaviral proteins archived in the Protein Data Bank were used to analyze viral proteome evolution during the first six months of the COVID-19 pandemic. Analyses of spatial locations, chemical pr
Autor:
Dina Popova, Isabel Gameiro-Ros, Mark M. Youssef, Petronio Zalamea, Ayeshia D. Morris, Iya Prytkova, Azadeh Jadali, Kelvin Y. Kwan, Chella Kamarajan, Jessica E. Salvatore, Xiaoling Xuei, David B. Chorlian, Bernice Porjesz, Samuel Kuperman, Danielle M. Dick, Alison Goate, Howard J. Edenberg, Jay A. Tischfield, Zhiping P. Pang, Paul A. Slesinger, Ronald P. Hart
Publikováno v:
Molecular psychiatry.
Synonymous and noncoding single nucleotide polymorphisms (SNPs) in the KCNJ6 gene, encoding G protein-gated inwardly rectifying potassium (GIRK2) channel subunit 2, have been linked with increased electroencephalographic frontal theta event-related o