Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jay A. Blundon"'
Autor:
Ildar T. Bayazitov, Brett J.W. Teubner, Feng Feng, Zhaofa Wu, Yulong Li, Jay A. Blundon, Stanislav S. Zakharenko
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113758- (2024)
Summary: Meaningful auditory memories are formed in adults when acoustic information is delivered to the auditory cortex during heightened states of attention, vigilance, or alertness, as mediated by neuromodulatory circuits. Here, we identify that,
Externí odkaz:
https://doaj.org/article/f1b401eb1b054cd1855edbe28624e815
Autor:
Tae-Yeon Eom, Seung Baek Han, Jieun Kim, Jay A. Blundon, Yong-Dong Wang, Jing Yu, Kara Anderson, Damian B. Kaminski, Sadie Miki Sakurada, Shondra M. Pruett-Miller, Linda Horner, Ben Wagner, Camenzind G. Robinson, Matthew Eicholtz, Derek C. Rose, Stanislav S. Zakharenko
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Schizophrenia is associated with brain ventricular enlargement. Here, the authors show in mice that 22q11 deletion, which is associated with schizophrenia, causes ventricular enlargement and motility abnormalities in cilia lining ventricle walls via
Externí odkaz:
https://doaj.org/article/015f5351a7344fa99035595c0123d9f5
Autor:
Christopher M. Davenport, Brett J.W. Teubner, Seung Baek Han, Mary H. Patton, Tae-Yeon Eom, Dusan Garic, Benjamin J. Lansdell, Abbas Shirinifard, Ti-Cheng Chang, Jonathon Klein, Shondra M. Pruett-Miller, Jay A. Blundon, Stanislav S. Zakharenko
Publikováno v:
Cell. 185(21)
Williams-Beuren syndrome (WBS) is a rare disorder caused by hemizygous microdeletion of ∼27 contiguous genes. Despite neurodevelopmental and cognitive deficits, individuals with WBS have spared or enhanced musical and auditory abilities, potentiall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a762c6be3ccc53baf17d20fb6d4762
https://pubmed.ncbi.nlm.nih.gov/36152627
https://pubmed.ncbi.nlm.nih.gov/36152627
Autor:
Jieun Kim, Derek C. Rose, Seung Baek Han, Kara Anderson, Yong-Dong Wang, Jing Yu, Matthew Eicholtz, Camenzind G. Robinson, Sadie Miki Sakurada, Ben Wagner, Jay A. Blundon, Stanislav S. Zakharenko, Tae-Yeon Eom, Shondra M. Pruett-Miller, Linda Horner, Damian B. Kaminski
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Progressive ventricular enlargement, a key feature of several neurologic and psychiatric diseases, is mediated by unknown mechanisms. Here, using murine models of 22q11-deletion syndrome (22q11DS), which is associated with schizophrenia in humans, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5cde0810d3bec010a7d00ffc6450a38
http://europepmc.org/articles/PMC7021727
http://europepmc.org/articles/PMC7021727
Cortical circuits are particularly sensitive to incoming sensory information during well-defined intervals of postnatal development called 'critical periods'. The critical period for cortical plasticity closes in adults, thus restricting the brain's
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e950df2f361635a5e8b7ab6a1b8b5da6
https://europepmc.org/articles/PMC6361689/
https://europepmc.org/articles/PMC6361689/
Publikováno v:
Deep Learning in Medical Image Analysis and Multimodal Learning for Clinical Decision Support ISBN: 9783319675572
DLMIA/ML-CDS@MICCAI
DLMIA/ML-CDS@MICCAI
Calcium imaging is a technique for observing neuron activity as a series of images showing indicator fluorescence over time. Manually segmenting neurons is time-consuming, leading to research on automated calcium imaging segmentation (ACIS). We evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3eb994eaf25afd888a1c450ee551fbbf
https://doi.org/10.1007/978-3-319-67558-9_33
https://doi.org/10.1007/978-3-319-67558-9_33
Autor:
Ildar T. Bayazitov, Donnie Eddins, Amar K. Pani, Richard J. Smeyne, Jay A. Blundon, Joby J. Westmoreland, Sungkun Chun, Jing Yu, Stanislav S. Zakharenko
Publikováno v:
Science. 344:1178-1182
Auditory hallucinations in schizophrenia are alleviated by antipsychotic agents that inhibit D2 dopamine receptors (Drd2s). The defective neural circuits and mechanisms of their sensitivity to antipsychotics are unknown. We identified a specific disr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a2f12b6e652d8f3ccc8f7a27cf9d83a
https://doi.org/10.1126/science.1253895
https://doi.org/10.1126/science.1253895
Publikováno v:
The Neuroscientist. 19:465-478
Sensory cortices can not only detect and analyze incoming sensory information but can also undergo plastic changes while learning behaviorally important sensory cues. This experience-dependent cortical plasticity is essential for shaping and modifyin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21f244fdff65fd3e26674269c0d12f3b
https://doi.org/10.1177/1073858413482983
https://doi.org/10.1177/1073858413482983
Autor:
Pradeep K. Vuppala, Derek C. Rose, Troy A. Hackett, Stanislav S. Zakharenko, Noah C. Roy, Seung Baek Han, K. Jake Sample, Burgess B. Freeman, Brett J. W. Teubner, Tae-Yeon Eom, Amar K. Pani, Ryan A. Kerekes, Jay A. Blundon, Richard J. Smeyne, Jing Yu
Publikováno v:
Science (New York, N.Y.). 356(6345)
Reopening a critical period Young brains, compared with adult brains, are plastic. This phenomenon has given rise to the concept of critical periods, during which acquisition of certain skills is optimal. In mice, an auditory critical period is only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e78d2cca0226b444968dacd3f6f51f8f
https://pubmed.ncbi.nlm.nih.gov/28663458
https://pubmed.ncbi.nlm.nih.gov/28663458
Publikováno v:
The Journal of Neuroscience. 31:16012-16025
Thalamocortical (TC) projections provide the major pathway for ascending sensory information to the mammalian neocortex. Arrays of these projections form synaptic inputs on thalamorecipient neurons, thus contributing to the formation of receptive fie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd5e30eb15a299524a8586c0bd7e002d
https://doi.org/10.1523/jneurosci.3281-11.2011
https://doi.org/10.1523/jneurosci.3281-11.2011