Zobrazeno 1 - 10 of 266 pro vyhledávání: '"Jay A Nadel"'
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Akademický článek
Normal CFTR inhibits epidermal growth factor receptor-dependent pro-inflammatory chemokine production in human airway epithelial cells.
Autor: Suil Kim, Brittney A Beyer, Courtney Lewis, Jay A Nadel
Publikováno v: PLoS ONE, Vol 8, Iss 8, p e72981 (2013)
Mutations in cystic fibrosis transmembrane conductance regulator (CFTR) protein cause cystic fibrosis, a disease characterized by exaggerated airway epithelial production of the neutrophil chemokine interleukin (IL)-8, which results in exuberant neut
Externí odkaz: https://doaj.org/article/de0157c8718045f2822f7170d925ddd5
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4
Normal Routine Spirometry Can Mask COPD/Emphysema in Symptomatic Smokers
Autor: Christine Fraser, Alfred Yamamoto, Marc Decramer, Jay A. Nadel, Mark J. Schein, Roxanna Moridzadeh, James C. Hogg, Diem Tran, Eric F. Glassy, Eric Verbeken, Donald P. Tashkin, Arthur F. Gelb
Publikováno v: Chronic Obstr Pulm Dis
Chronic obstructive pulmonary diseases (Miami, Fla.), vol 8, iss 1
BACKGROUND: Recent studies have emphasized the difficulty of early detection of chronic obstructive pulmonary disease (COPD) in symptomatic smokers with normal routine spirometry. This includes post-bronchodilator normal forced expiratory volume in 1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f6896f4c4152d3dae782fd378862e0
https://europepmc.org/articles/PMC8047618/
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6
Understanding the pathophysiology of the asthma–chronic obstructive pulmonary disease overlap syndrome
Autor: Jay A. Nadel, Stephanie A. Christenson, Arthur F. Gelb
Publikováno v: Current Opinion in Pulmonary Medicine. 22:100-105
Purpose of review The review will provide an update on the pathophysiology and studies of inflammation associated with the asthma-chronic obstructive pulmonary disease (COPD) overlap syndrome (ACOS) and the mechanism(s) responsible for persistent exp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1e2b93750c9bc609964564846a7c8b
https://doi.org/10.1097/mcp.0000000000000236
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7
Respiratory syncytial virus activates epidermal growth factor receptor to suppress interferon regulatory factor 1-dependent interferon-lambda and antiviral defense in airway epithelium
Autor: B.J. Clark, C. Dela Cruz, Jonathan L. Koff, Y. Sun, Iris F. Ueki, Arielle M. Mulenos, Jay A. Nadel, Awo Osafo-Addo, Wei Liu, April Kalinowski, Benjamin T. Galen, J Joerns
Publikováno v: Mucosal immunology, vol 11, iss 3
Mucosal immunology
Respiratory syncytial virus (RSV) persists as a significant human pathogen that continues to contribute to morbidity and mortality. In children, RSV is the leading cause of lower respiratory tract infections, and in adults RSV causes pneumonia and co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce51e5b33d3c828c72410e499621eee6
https://escholarship.org/uc/item/15p4s98h
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8
Unraveling the Pathophysiology of the Asthma-COPD Overlap Syndrome
Autor: Alfred Yamamoto, Jay A. Nadel, Eric Verbeken, Arthur F. Gelb
Publikováno v: Chest. 148:313-320
Investigators believe most patients with asthma have reversible airflow obstruction with treatment, despite airway remodeling and hyperresponsiveness. There are smokers with chronic expiratory airflow obstruction despite treatment who have features o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c91a6d71dda07237af7879e7e53e5ad
https://doi.org/10.1378/chest.14-2483
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