Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jay A Bowman-Kirigin"'
Autor:
David M Kranz, Michael J White, Mao Li, Maximilian O Schaettler, Rupen Desai, Anthony Z Wang, Alexandra J Livingstone, Dale K Kobayashi, Andrew T Coxon, Jay A Bowman-Kirigin, Connor J Liu, Diane E Bender, Tanner M Johanns, Gavin P Dunn
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 2 (2023)
Background Adoptive cellular therapies with chimeric antigen receptor T cells have revolutionized the treatment of some malignancies but have shown limited efficacy in solid tumors such as glioblastoma and face a scarcity of safe therapeutic targets.
Externí odkaz:
https://doaj.org/article/67ba15afade74b8a9caa7534c5ef5ce0
Autor:
Christopher C Gibson, Chadwick T Davis, Weiquan Zhu, Jay A Bowman-Kirigin, Ashley E Walker, Zhengfu Tai, Kirk R Thomas, Anthony J Donato, Lisa A Lesniewski, Dean Y Li
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140370 (2015)
Vitamin D is a known modulator of inflammation. Native dietary vitamin D3 is thought to be bio-inactive, and beneficial vitamin D3 effects are thought to be largely mediated by the metabolite 1,25(OH)2D3. Reduced serum levels of the most commonly mea
Externí odkaz:
https://doaj.org/article/e8790ceb20744644be7a87d0c72576e4
Autor:
Jay A. Bowman-Kirigin, Rupen Desai, Brian T. Saunders, Anthony Z. Wang, Maximilian O. Schaettler, Connor J. Liu, Alexandra J. Livingstone, Dale K. Kobayashi, Vivek Durai, Nicole M. Kretzer, Gregory J. Zipfel, Eric C. Leuthardt, Joshua W. Osbun, Michael R. Chicoine, Albert H. Kim, Kenneth M. Murphy, Tanner M. Johanns, Bernd H. Zinselmeyer, Gavin P. Dunn
Publikováno v:
Cancer Immunology Research. 11:20-37
The central nervous system (CNS) antigen-presenting cell (APC) that primes antitumor CD8+ T-cell responses remains undefined. Elsewhere in the body, the conventional dendritic cell 1 (cDC1) performs this role. However, steady-state brain parenchyma c
Autor:
Gavin P. Dunn, Bernd H. Zinselmeyer, Tanner M. Johanns, Kenneth M. Murphy, Albert H. Kim, Michael R. Chicoine, Joshua W. Osbun, Eric C. Leuthardt, Gregory J. Zipfel, Nicole M. Kretzer, Vivek Durai, Dale K. Kobayashi, Alexandra J. Livingstone, Connor J. Liu, Maximilian O. Schaettler, Anthony Z. Wang, Brian T. Saunders, Rupen Desai, Jay A. Bowman-Kirigin
Supplementary Figures and Tables.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ee81d152485914d2570e049914be76
https://doi.org/10.1158/2326-6066.22546134.v1
https://doi.org/10.1158/2326-6066.22546134.v1
Autor:
Gavin P. Dunn, Bernd H. Zinselmeyer, Tanner M. Johanns, Kenneth M. Murphy, Albert H. Kim, Michael R. Chicoine, Joshua W. Osbun, Eric C. Leuthardt, Gregory J. Zipfel, Nicole M. Kretzer, Vivek Durai, Dale K. Kobayashi, Alexandra J. Livingstone, Connor J. Liu, Maximilian O. Schaettler, Anthony Z. Wang, Brian T. Saunders, Rupen Desai, Jay A. Bowman-Kirigin
The central nervous system (CNS) antigen-presenting cell (APC) that primes antitumor CD8+ T-cell responses remains undefined. Elsewhere in the body, the conventional dendritic cell 1 (cDC1) performs this role. However, steady-state brain parenchyma c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb45f311006488389e8bbe0e0d51222
https://doi.org/10.1158/2326-6066.c.6551106
https://doi.org/10.1158/2326-6066.c.6551106
Autor:
Maximilian O Schaettler, Rupen Desai, Anthony Z Wang, Alexandra J Livingstone, Dale K Kobayashi, Andrew T Coxon, Jay A Bowman-Kirigin, Connor J Liu, Mao Li, Diane E Bender, Michael J White, David M Kranz, Tanner M Johanns, Gavin P Dunn
Publikováno v:
Journal for ImmunoTherapy of Cancer. 11:e006121
BackgroundAdoptive cellular therapies with chimeric antigen receptor T cells have revolutionized the treatment of some malignancies but have shown limited efficacy in solid tumors such as glioblastoma and face a scarcity of safe therapeutic targets.
Autor:
Tanner M. Johanns, Dale K. Kobayashi, Eric C. Leuthardt, Albert H. Kim, Brian Saunders, Gavin P. Dunn, Joshua W. Osbun, Gregory J. Zipfel, Rupen Desai, Alexandra J. Livingstone, Vivek Durai, Max Schaettler, Connor J. Liu, Nicole M. Kretzer, Bernd H. Zinselmeyer, Michael R. Chicoine, Kenneth M. Murphy, Jay A. Bowman-Kirigin, Anthony Z. Wang
The central nervous system (CNS) antigen presenting cell (APC) which primes anti-tumor CD8+ T cell responses remains undefined. Elsewhere, the conventional dendritic cell 1 (cDC1) performs this role. However, steady-state brain cDC1 are rare; cDC loc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cb8256bd397b7d60fca7c7827161430
https://doi.org/10.1101/2021.09.13.460088
https://doi.org/10.1101/2021.09.13.460088
Autor:
Anthony Z. Wang, Jay A. Bowman-Kirigin, Rupen Desai, Liang-I Kang, Pujan R. Patel, Bhuvic Patel, Saad M. Khan, Diane Bender, M. Caleb Marlin, Jingxian Liu, Joshua W. Osbun, Eric C. Leuthardt, Michael R. Chicoine, Ralph G. Dacey, Gregory J. Zipfel, Albert H. Kim, David G. DeNardo, Allegra A. Petti, Gavin P. Dunn
Publikováno v:
Genome medicine. 14(1)
Background Recent investigations of the meninges have highlighted the importance of the dura layer in central nervous system immune surveillance beyond a purely structural role. However, our understanding of the meninges largely stems from the use of
Autor:
Ralph G. Dacey, Rupen Desai, Michael R. Chicoine, Jay A. Bowman-Kirigin, Gregory J. Zipfel, Joshua W. Osbun, Gavin P. Dunn, M. Caleb Marlin, Anthony Z. Wang, Allegra A. Petti, Pujan R. Patel, Bhuvic Patel, Diane Bender, Eric C. Leuthardt, Albert H. Kim, Jingxian Liu, Saad M. Khan
Recent investigation of the meninges, specifically the dura layer, has highlighted its importance in CNS immune surveillance beyond a purely structural role. However, most of our understanding of the meninges stems from the use of pre-clinical models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ac679a171fa9f3fd559a488ceb5ff33
https://doi.org/10.1101/2021.08.03.454066
https://doi.org/10.1101/2021.08.03.454066
Autor:
Jay A. Bowman-Kirigin, Yu Tao, Tanner M. Johanns, Jingqin Luo, Diane G. Kelley, Diane D. Mao, Maximilian Schaettler, Gavin P. Dunn, Connor J. Liu, Albert H. Kim, Ian F. Dunn, Wenya Linda Bi, Ravindra Uppaluri, Dale K. Kobayashi, Yujie Fu, Diane Bender
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Encouraging clinical results using immune checkpoint therapies to target the PD-1 axis in a variety of cancer types have paved the way for new immune therapy trials in brain tumor patients. However, the molecular mechanisms that regulate expression o