Zobrazeno 1 - 10
of 478
pro vyhledávání: '"Jay A Berzofsky"'
Autor:
Jay A Berzofsky, William Becker, Noriko Seishima, Purevdorj B Olkhanud, Paloma A Moreno, Katherine C Goldfarbmuren, Hoyoung M Maeng
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
Background Despite advances in checkpoint inhibitor (CPI) therapy for cancer treatment, many cancers remain resistant. Tumors deemed “cold” based on lack of T cell infiltration show reduced potential for CPI therapy. Cancer vaccines may overcome
Externí odkaz:
https://doaj.org/article/37884bc06a154cd2a0599f208c526cba
Publikováno v:
PLoS Pathogens, Vol 15, Iss 2, p e1007614 (2019)
The mucosal surface of the intestinal tract represents a major entry route for many microbes. Despite recent progress in the understanding of the IL-21/IL-21R signaling axis in the generation of germinal center B cells, the roles played by this signa
Externí odkaz:
https://doaj.org/article/f4cfab3b42984270bf696f4e57c28744
Autor:
Yongjun Sui, Blake Frey, Yichuan Wang, Rolf Billeskov, Shweta Kulkarni, Katherine McKinnon, Tracy Rourke, Linda Fritts, Christopher J Miller, Jay A Berzofsky
Publikováno v:
PLoS Pathogens, Vol 13, Iss 5, p e1006395 (2017)
Myeloid derived suppressor cells (MDSCs), which suppress anti-tumor or anti-viral immune responses, are expanded in the peripheral blood and tissues of patients/animals with cancer or viral infectious diseases. We here show that in chronic SIV infect
Externí odkaz:
https://doaj.org/article/56729a0c7b154d3c8586487af6482dbe
Publikováno v:
Frontiers in Immunology, Vol 5 (2014)
CD1d-restricted natural killer T (NKT) cells lie at the interface between the innate and adaptive immune systems and are important mediators of immune responses and tumor immunosurveillance. These NKT cells uniquely recognize lipid antigens, and thei
Externí odkaz:
https://doaj.org/article/49cba5b085db4a5bac31c9ea650dceca
Autor:
John C Morris, Antoinette R Tan, Thomas E Olencki, Geoffrey I Shapiro, Bruce J Dezube, Michael Reiss, Frank J Hsu, Jay A Berzofsky, Donald P Lawrence
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90353 (2014)
In advanced cancers, transforming growth factor-beta (TGFβ) promotes tumor growth and metastases and suppresses host antitumor immunity. GC1008 is a human anti-TGFβ monoclonal antibody that neutralizes all isoforms of TGFβ. Here, the safety and ac
Externí odkaz:
https://doaj.org/article/0353ebcc11b249188233f547e8275d23
Autor:
Yi-Hsiang Huang, Masaki Terabe, C David Pendleton, Deborah Stewart Khursigara, Tapan K Bera, Ira Pastan, Jay A Berzofsky
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e64365 (2013)
Identification of CD8(+) T cell epitopes that can induce T cells to kill tumor cells is a fundamental step for development of a peptide cancer vaccine. POTE protein is a newly identified cancer antigen that was found to be expressed in a wide variety
Externí odkaz:
https://doaj.org/article/e287a5b843b0419f8d53a1ca0ea0bf16
Autor:
Miranda S Oakley, Victoria Majam, Babita Mahajan, Noel Gerald, Vivek Anantharaman, Jerrold M Ward, Lawrence J Faucette, Thomas F McCutchan, Hong Zheng, Masaki Terabe, Jay A Berzofsky, L Aravind, Sanjai Kumar
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6793 (2009)
An in-depth knowledge of the host molecules and biological pathways that contribute towards the pathogenesis of cerebral malaria would help guide the development of novel prognostics and therapeutics. Genome-wide transcriptional profiling of the brai
Externí odkaz:
https://doaj.org/article/2f4846b49ab440dbad1384481861b27b
Autor:
Samir N. Khleif, Theresa L. Whiteside, Jay A. Berzofsky, Mikayel Mkrtichyan, Nadya Tarasova, Andrea Carnie, Jiahua Qian, Willie Wilson, Saudat Adamson-Fadeyi, Rasha Abu Eid, Magis Mandapathil, Stephanie Zdanov
Supplemental Figure 1 Legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4d0b7d175f63487ebc00094a4431b2
https://doi.org/10.1158/2326-6066.22538870.v1
https://doi.org/10.1158/2326-6066.22538870.v1
Autor:
Ira Pastan, Yoram Reiter, Chin-Hsien Tai, Gerhard Niederfellner, Birgit Bossenmaier, Jay A. Berzofsky, Masaki Terabe, Tapan K. Bera, Xiufen Liu, James O'Brien, Yasmin Leshem
Fig S1. Description of DNA constructs Fig S2. Distribution of intra-tumoral injected trypan blue Fig S3. Combination of intra-tumoral immunotoxins with anti-CTLA-4 is well tolerated by mice. Fig S4. Anti-tumor effect of anti-CTLA-4 and LMB-100 depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb4008cc6b1c9634a3d190ca22b5fe6
https://doi.org/10.1158/2326-6066.22539379
https://doi.org/10.1158/2326-6066.22539379