Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jay, Soto"'
Autor:
Timothy Kilchenmann, Lynne Verselis, Liping Jin, Christian Gossens, Michael Lindemann, Andreas U. Monsch, Detlef Wolf, Ronald B. Postuma, Jay Soto, Wei-Yi Cheng, Anirvan Ghosh, Frank G. Boess, Michael Grundman, Martin Koller, Alf Scotland, Florian Lipsmeier, Thomas Kremer, Kirsten I. Taylor, Juliane Siebourg-Polster, Ignacio Fernandez‐Garcia, Jens Schjodt-Eriksen, Christian Czech
Publikováno v:
Movement Disorders. 33:1287-1297
Background: Ubiquitous digital technologies such as smartphone sensors promise to fundamentally change biomedical research and treatment monitoring in neurological diseases such as PD, creating a new domain of digital biomarkers. Objectives: The pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6085532f1c36de644a7638a98c6cac6
https://doi.org/10.1002/mds.27376
https://doi.org/10.1002/mds.27376
Autor:
Gene G. Kinney, Wagner Zago, Martin Koller, Jay Soto, Daniel K. Ness, Michael Grundman, Dale Schenk, Susanne Ostrowitzki, Sue G. Griffith, George Atiee
Publikováno v:
Movement Disorders. 32:211-218
Background: α-Synuclein is a major component of pathologic inclusions that characterize Parkinson's disease. PRX002 is an antibody that targets α-synuclein, and its murine parent antibody 9E4 has been shown in preclinical studies to reduce α-synuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf3aa3e3b2c08919ca651cb1053cbff5
https://doi.org/10.1002/mds.26878
https://doi.org/10.1002/mds.26878
Autor:
Frank G. Boess, Susanne Ostrowitzki, Beth Safirstein, Joseph Jankovic, Meret Martin-Facklam, Omid Omidvar, Jay Soto, Stuart Isaacson, Tonya K. Marmon, Aaron Ellenbogen, Sue G. Griffith, Joseph F. Quinn, Michael Grundman, Dale Schenk, Daniel Ness, Gene G. Kinney, Wagner Zago, Ira J. Goodman, Martin Koller
Publikováno v:
JAMA neurology. 75(10)
Importance Aggregated α-synuclein is believed to be central to the pathogenesis of Parkinson disease (PD). PRX002/RG7935 (PRX002) is a humanized monoclonal antibody designed to target aggregated forms of α-synuclein, thereby inhibiting neuron-to-ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d5b85efcf3beacd5fa15868dc4d355
https://pubmed.ncbi.nlm.nih.gov/29913004
https://pubmed.ncbi.nlm.nih.gov/29913004
Autor:
Martin Koller, Juliane Siebourg-Polster, Alf Scotland, Christian Gossens, Thomas Kremer, Jay Soto, Machael Grundman, Andrew Creigh, Jens Schjodt-Eriksen, Florian Lipsmeier, Michael Lindemann, Wei-Yi Cheng, Anirvan Ghosh, Ronald B. Postuma, Liping Jin, Lynne Verselis, Detlef Wolf, Christian Czech, Frank G. Boess, Timothy Kilchenmann, Andreas U. Monsch, Ignacio Fernandez Garcia, Yan-Ping Zhang-Schaerer, Kirsten I. Taylor, Meret Martin Facklam
Publikováno v:
Lecture Notes of the Institute for Computer Sciences, Social Informatics and Telecommunications Engineering ISBN: 9783319985503
MobiHealth
MobiHealth
Smartphone-based assessments have been considered a potential solution for continuously monitoring gait and mobility in mild to moderate Parkinson’s disease (PD) patients. Forty-four PD patients from cohorts 4 to 6 of the Multiple Ascending Dose (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82c00e5e4cc248f1b00b2569afddab97
https://doi.org/10.1007/978-3-319-98551-0_2
https://doi.org/10.1007/978-3-319-98551-0_2
Autor:
Ignacio Fernandez Garcia, Florian Lipsmeier, Michael Lindemann, Liping Jin, Detlef Wolf, Timothy Kilchenmann, Jens Schjodt-Eriksen, Kirsten I. Taylor, Christian Gossens, Wei-Yi Cheng, Meret Martin Facklam, Andreas U. Monsch, Martin Koller, Alf Scotland, Lynne Verselis, Yan-Ping Zhang-Schaerer, Andrew P. Creagh, Juliane Siebourg-Polster, Anirvan Ghosh, Christian Czech, Thomas Kremer, Jay Soto, Michael Grundman, Frank G. Boess, Ronald B. Postuma
Publikováno v:
2017 IEEE Life Sciences Conference (LSC).
Smartphone-based remote monitoring is a potential solution for providing long-term, objective assessment of gait and mobility in patients with Parkinsons disease (PD). In the Multiple Ascending Dose study of PRX002/RG7935, forty-four mild to moderate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3505d00bc0574b31c9968f3c87109ae4
https://doi.org/10.1109/lsc.2017.8268169
https://doi.org/10.1109/lsc.2017.8268169
Autor:
Christian Gossens, Ron Postuma, Frank G. Boess, Christian Czech, Martin Koller, Thomas Kremer, Wei-Yi Cheng, Yan-Ping Zhang-Schaerer, Kirsten I. Taylor, Jay Soto, Andreas U. Monsch, Michael Lindemann, Meret Martin-Facklam, Anirvan Ghosh, Jens Schjodt-Eriksen, Michael Grundman, Juliane Siebourg-Polster, Ignacio Fernandez Garcia, Timothy Kilchenmann, Florian Lipsmeier, Liping Jin, Detlef Wolf, Alf Scotland, Lynne Verselis
Publikováno v:
CHASE
Smartphone-based assessments have been considered a potential solution to passively monitor gait and mobility in early-stage Parkinson's disease (PD) patients. In the Multiple Ascending Dose clinical trial of PRX002/RG7935, 44 PD patients and 35 age-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f0c3fcd1c1b024c10c03fa3a8813231
https://doi.org/10.1109/chase.2017.87
https://doi.org/10.1109/chase.2017.87
Autor:
Dale B, Schenk, Martin, Koller, Daniel K, Ness, Sue G, Griffith, Michael, Grundman, Wagner, Zago, Jay, Soto, George, Atiee, Susanne, Ostrowitzki, Gene G, Kinney
Publikováno v:
Movement disorders : official journal of the Movement Disorder Society. 32(2)
α-Synuclein is a major component of pathologic inclusions that characterize Parkinson's disease. PRX002 is an antibody that targets α-synuclein, and its murine parent antibody 9E4 has been shown in preclinical studies to reduce α-synuclein patholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7030ce2237f0bc8eee5eb1ac59101781
https://pubmed.ncbi.nlm.nih.gov/28218461
https://pubmed.ncbi.nlm.nih.gov/28218461
Publikováno v:
Alzheimer's & Dementia. 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d642d3fef0685e8d34cb1916c5f5fe8a
https://doi.org/10.1016/j.jalz.2013.05.576
https://doi.org/10.1016/j.jalz.2013.05.576