Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Jaxaira Maggi"'
1
Akademický článek
Regulation of Tolerogenic Features on Dexamethasone-Modulated MPLA-Activated Dendritic Cells by MYC
Autor: Paulina A. García-González, Jaxaira Maggi, Katina Schinnerling, Alejandro Sepúlveda-Gutiérrez, Lilian Soto, Oscar Neira, Ahmed M. Mehdi, Hendrik J. Nel, Bárbara Pesce, Octavio Aravena, María Carmen Molina, Diego Catalán, Ranjeny Thomas, Ricardo A. Verdugo, Juan Carlos Aguillón
Publikováno v: Frontiers in Immunology, Vol 10 (2019)
The potential of tolerogenic dendritic cells (tolDCs) to shape immune responses and restore tolerance has turn them into a promising therapeutic tool for cellular therapies directed toward immune regulation in autoimmunity. Although the cellular mech
Externí odkaz: https://doaj.org/article/7fb74e75ba6b42cab167b149b15c222c
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2
Akademický článek
Dexamethasone and Monophosphoryl Lipid A Induce a Distinctive Profile on Monocyte-Derived Dendritic Cells through Transcriptional Modulation of Genes Associated With Essential Processes of the Immune Response
Autor: Paulina A. García-González, Katina Schinnerling, Alejandro Sepúlveda-Gutiérrez, Jaxaira Maggi, Ahmed M. Mehdi, Hendrik J. Nel, Bárbara Pesce, Milton L. Larrondo, Octavio Aravena, María C. Molina, Diego Catalán, Ranjeny Thomas, Ricardo A. Verdugo, Juan C. Aguillón
Publikováno v: Frontiers in Immunology, Vol 8 (2017)
There is growing interest in the use of tolerogenic dendritic cells (tolDCs) as a potential target for immunotherapy. However, the molecular bases that drive the differentiation of monocyte-derived DCs (moDCs) toward a tolerogenic state are still poo
Externí odkaz: https://doaj.org/article/f7d45918c8324f22a733ba8475b062f6
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4
Akademický článek
Dexamethasone and monophosphoryl lipid A-modulated dendritic cells promote antigen-specific tolerogenic properties on naïve and memory CD4+ T cells
Autor: Jaxaira Maggi, Katina Schinnerling, Bárbara Pesce, Catharien M Hilkens, Diego Catalán, Juan C Aguillón
Publikováno v: Frontiers in Immunology, Vol 7 (2016)
Tolerogenic dendritic cells (DCs) are a promising tool to control T cell-mediated autoimmunity. Here, we evaluate the ability of dexamethasone-modulated and monophosphoryl lipid A-activated DCs (MPLA-tDCs) to exert immunomodulatory effects on naïve
Externí odkaz: https://doaj.org/article/39b4901bec31430e83155c9668681fe6
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6
Isolation of HLA-DR-naturally presented peptides identifies T-cell epitopes for rheumatoid arthritis
Autor: Jaxaira Maggi, Montserrat Carrascal, Lilian Soto, Oscar Neira, María C Cuéllar, Octavio Aravena, Eddie A James, Joaquin Abian, Dolores Jaraquemada, Diego Catalan, Juan C Aguillón
Publikováno v: Annals of the Rheumatic Diseases 81: 1096-1105 (2022).
Objective Rheumatoid arthritis (RA) immunopathogenesis revolves around the presentation of poorly characterised self-peptides by human leucocyte antigen (HLA)-class II molecules on the surface of antigen-presenting cells to autoreactive CD4 +T cells.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191c50d5510e0094055e847c2db2cc96
http://hdl.handle.net/10261/288129
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7
Dexamethasone and Monophosphoryl Lipid A-Modulated Dendritic Cells Promote Antigen-Specific Tolerogenic Properties on Naive and Memory CD4+ T Cells
Autor: Juan Carlos Aguillón, Diego Catalán, Katina Schinnerling, Jaxaira Maggi, Barbara Pesce, Catharien M. U. Hilkens
Publikováno v: Frontiers in Immunology
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Tolerogenic dendritic cells (DCs) are a promising tool to control T cell-mediated autoimmunity. Here, we evaluate the ability of dexamethasone-modulated and monophosphoryl lipid A (MPLA)-activated DCs [MPLA-tolerogenic DCs (tDCs)] to exert immunomodu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::481a8c383e061afa365ea2c4d38693d7
https://doi.org/10.3389/fimmu.2016.00359
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8
Therapeutic potential of hyporesponsive CD4+ T cells in autoimmunity
Autor: Carolina Schäfer, Jaxaira Maggi, Diego Catalán, Juan Carlos Aguillón, Katina Schinnerling, Gabriela Ubilla-Olguín
Publikováno v: Frontiers in Immunology, Vol 6 (2015)
Frontiers in Immunology
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
The interaction between dendritic cells (DCs) and T cells is crucial on immunity or tolerance induction. In an immature or semi-mature state, DCs induce tolerance through T-cell deletion, generation of regulatory T cells, and/or induction of T-cell a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49cfef01b56ca9f7c26caddcb059cbe1
http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00488/full
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9
A short protocol using dexamethasone and monophosphoryllipid a generates tolerogenic dendritic cells that display apotent migratory capacity to lymphoid chemokines
Autor: Javier Campos, Paulina A García-González, Rodrigo González, Jaxaira Maggi, Diego Catalán, Karina Pino-Lagos, David Gárate, Milton Larrondo, Barbara Pesce, Lorena Hoyos, Pia Tobar, Verónica Ramos, Lilian Soto, Juan Carlos Aguillón, Rodrigo Morales, María Carmen Molina
Publikováno v: JOURNAL OF TRANSLATIONAL MEDICINE
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Journal of Translational Medicine
Background Generation of tolerogenic dendritic cells (TolDCs) for therapy is challenging due to its implications for the design of protocols suitable for clinical applications, which means not only using safe products, but also working at defining sp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7712e69e7aa655908f0cf17653f830f
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