Výsledky vyhledávání - "Jawzah Alnakhli"

Synthesis and Antiproliferative Activities of Triphenylmethanol Conjugates of Leuprorelin

Autor: Kaleh Karim, William Y. Boadi, Ryan Beni, Jawzah Alnakhli, Samiyah Alhamed

Publikováno v: Open Journal of Medicinal Chemistry. :37-47

Leuprorelin® (LEP) is an FDA drug for breast cancer and prostate cancer treatment. There are several reported adverse effects such as transient hypertension, excessive salivation, and increased dysuria during treatment with LEP. In this study, the e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::efacf00349decdf5d162cfe44cd6452b
https://doi.org/10.4236/ojmc.2019.92002

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Triphenylmethanol and Tris(2-(hydroxymethyl)phenol) Derivatives: Synthesis and Application as Indicators for Acid-Base Volumetric Titration

Autor: Melanie Mootry, Tralynn Williams, Shania Richardson, Samiyah Alhamed, Jawzah Alnakhli, William Y. Boadi, Ryan Beni, Renner Antwi, Tiffany Robinson, Natalie Spicer, Anterrial Harris, Ibrahim Bamidad, Jamill Jackson, Nahom Iyob

Publikováno v: Journal of Analytical Sciences, Methods and Instrumentation. :13-21

Polyphenols are naturally occurring compounds found largely in fruits, vegetables, cereals and beverages. Currently, there is much interest in the potential health benefits of dietary plant polyphenols as antioxidants. The effect of polyphenols on hu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::16541d11447ff6c251307a363a097edd
https://doi.org/10.4236/jasmi.2019.92002

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Triphenylmethanol Conjugates of Triptorelin as Anti-Lipid Peroxidation Prodrugs

Autor: Jawzah Alnakhli, Samiyah Alhamed, William Y. Boadi, Ryan Beni

Publikováno v: Open Journal of Medicinal Chemistry. :49-62

Antioxidants are substances that can prevent or slow damage to cells caused by free radicals, unstable molecules that the body produces as a reaction to environmental and other pressures. Free radicals may play a role in heart disease, cancer and oth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b9e9e3dc7cd1ca7947d888758cdf3349
https://doi.org/10.4236/ojmc.2019.93003

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Abstract 2686: Polyphenolic triptorelin and leuprorelin derivatives as anticancer prodrugs

Autor: William Y. Boadi, Kaleh Karim, Jawzah Alnakhli, Yousef Beni, Samiyah Alhamed

Publikováno v: Cancer Research. 78:2686-2686

Triptorelin (TRP) and Leuprorelin (LEP) are two synthetic analogue of gonadotropin-releasing hormone (GnRH), first was approved by the FDA for treatment of advanced prostate cancer and endometriosis in mid 80s. The surge of testosterone, known as a f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ab850c224c11610f63f231e7fd3f4e2
https://doi.org/10.1158/1538-7445.am2018-2686

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Abstract 4807: Triphenylmethanol conjugates of triptorelin as anti-cancer prodrugs

Autor: Ryan Beni, Jawzah Alnakhli, William Y. Boadi

Publikováno v: Cancer Research. 76:4807-4807

Triptorelin (TRP) is an anti-cancer agent used for the treatment of a wide variety of hormone-responsive cancers, such as prostate cancer. The surge of testosterone, known as a flare effect, is the major side-effect of cancer chemotherapy using TRP i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a38a38ab223b12ae84261d467981399
https://doi.org/10.1158/1538-7445.am2016-4807

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