Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jawara Allen"'
Autor:
Annemarie Boleij, Payam Fathi, William Dalton, Ben Park, Xinqun Wu, David Huso, Jawara Allen, Sepideh Besharati, Robert A. Anders, Franck Housseau, Amanda E. Mackenzie, Laura Jenkins, Graeme. Milligan, Shaoguang Wu, Cynthia L. Sears
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Boleij et al. show that G protein-coupled receptor 35 (GPR35) regulates the responses to enterotoxigenic Bacteroides fragilis (ETBF) in colonic epithelial cells. They find that GPR35-deficiency nearly protected mice from ETBF-induced death, suggestin
Externí odkaz:
https://doaj.org/article/2986eba9551643dc8608d3a4c5b5b496
Autor:
Jawara Allen, Axel Rosendahl Huber, Cayetano Pleguezuelos-Manzano, Jens Puschhof, Shaoguang Wu, Xinqun Wu, Charelle Boot, Aurelia Saftien, Heather M. O’Hagan, Hao Wang, Ruben van Boxtel, Hans Clevers, Cynthia L. Sears
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT Enterotoxigenic Bacteroides fragilis (ETBF) is consistently found at higher frequency in individuals with sporadic and hereditary colorectal cancer (CRC) and induces tumorigenesis in several mouse models of CRC. However, whether specific mut
Externí odkaz:
https://doaj.org/article/c8b925b4810c4dcabf9cb25d68e6536b
Autor:
Jawara Allen, Cynthia L. Sears
Publikováno v:
Genome Medicine, Vol 11, Iss 1, Pp 1-18 (2019)
Abstract In recent years, the number of studies investigating the impact of the gut microbiome in colorectal cancer (CRC) has risen sharply. As a result, we now know that various microbes (and microbial communities) are found more frequently in the s
Externí odkaz:
https://doaj.org/article/849a45872c684a05a5e1b4d18ad9daa7
Publikováno v:
Journal of general internal medicine, vol 37, iss 9
Online education due to the COVID-19 pandemic caused many medical schools to increasingly employ asynchronous and virtual learning that favored student independence and flexibility. At the same time, the COVID-19 pandemic highlighted existing shortco
Autor:
Grant Wilson, Jiajia Zhang, Emma Spence, Maxwell White, Jawara Allen, Christopher Fan, Jessica Queen, Jarushka Naidoo, Cynthia L Sears, Fyza Shaikh
Publikováno v:
Open Forum Infectious Diseases. 9
Background Recent studies have suggested that antibiotic (ABX) use and resulting changes in the gut microbiome alter the efficacy of immune checkpoint inhibitors (ICIs) in cancer treatment, but detailed data are lacking. We performed a retrospective
Autor:
Robert A. Anders, Sepideh Besharati, Xinqun Wu, Franck Housseau, Payam Fathi, Jawara Allen, Laura Jenkins, Shaoguang Wu, David L. Huso, Amanda E. Mackenzie, Ben Park, Cynthia L. Sears, Graeme Milligan, Annemarie Boleij, William Brian Dalton
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology, 4
Communications Biology
Communications Biology, 4, 1
Communications Biology, 4
Communications Biology
Communications Biology, 4, 1
G protein-coupled receptor (GPR)35 is highly expressed in the gastro-intestinal tract, predominantly in colon epithelial cells (CEC), and has been associated with inflammatory bowel diseases (IBD), suggesting a role in gastrointestinal inflammation.
Autor:
Emily F. Davis-Marcisak, Fernando T. Zamuner, Michael Considine, Srinivasan Yegnasubramanian, Elana J. Fertig, Luciane T. Kagohara, Daria A. Gaykalova, Gaurav Sharma, Jawara Allen
Publikováno v:
British Journal of Cancer
Background Identifying potential resistance mechanisms while tumour cells still respond to therapy is critical to delay acquired resistance. Methods We generated the first comprehensive multi-omics, bulk and single-cell data in sensitive head and nec
Publikováno v:
Wellcome Open Research. 7:292
Background: COVID-19 variants threaten health globally. Despite improving vaccines and treatments, there is an urgent need for alternative strategies to prevent or reduce the severity of COVID-19. Potential strategies include probiotics, which are sa
Autor:
Susan J. Walker, Alexis N Gademsey, Jawara Allen, Logan Patterson, Pedro Costa-Pinheiro, Mark Kester, Xinqun Wu, Todd E. Fox, Nicholas C. Zachos, Jeremy Joseph Porter Shaw, Cynthia L. Sears, Isabella Posey, Shaoguang Wu
Publikováno v:
FASEB J
Enterotoxigenic Bacteroides fragilis (ETBF) is a commensal bacterium of great importance to human health due to its ability to induce colitis and cause colon tumor formation in mice through the production of B. fragilis toxin (BFT). The formation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee38024f6113d1223bd677af8dca64de
https://europepmc.org/articles/PMC8140605/
https://europepmc.org/articles/PMC8140605/
Autor:
Jawara Allen
Publikováno v:
The Journal of Infectious Diseases