Activation of the calcium sensing receptor increases claudin-14 expression via a PLC -p38-Sp1 pathway

Autor: Justin J Lee, Jawad Alzamil, Saba Rehman, R. Todd Alexander, Wanling Pan, Henrik Dimke

Publikováno v: Lee, J J, Alzamil, J, Rehman, S, Pan, W, Dimke, H & Alexander, R T 2021, ' Activation of the calcium sensing receptor increases claudin-14 expression via a PLC-p38-Sp1 pathway ', F A S E B Journal, vol. 35, no. 11, e21982 . https://doi.org/10.1096/fj.202002137RRR

Activation of the basolateral calcium sensing receptor (CaSR) in the renal tubular thick ascending limb (TAL) increases claudin-14 expression, which reduces paracellular calcium (Ca2+ ) permeability, thus increasing urinary Ca2+ excretion. However, t

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https://pubmed.ncbi.nlm.nih.gov/34694654