Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Jawaad, Sheriff"'
Autor:
Rukiye Tuna, Wenjuan Yi, Esmeralda Crespo Cruz, JP Romero, Yi Ren, Jingjiao Guan, Yan Li, Yuefan Deng, Danny Bluestein, Zixiang Leonardo Liu, Jawaad Sheriff
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4800 (2024)
Thrombosis is the pathological clot formation under abnormal hemodynamic conditions, which can result in vascular obstruction, causing ischemic strokes and myocardial infarction. Thrombus growth under moderate to low shear (−1) relies on platelet a
Externí odkaz:
https://doaj.org/article/190857efa7a349208595286ddb3cdbdd
Autor:
Daniel E. Palomares, Phat L. Tran, Catherine Jerman, Moe Momayez, Pierre Deymier, Jawaad Sheriff, Danny Bluestein, Sairam Parthasarathy, Marvin J. Slepian
Publikováno v:
Bioengineering, Vol 10, Iss 12, p 1414 (2023)
Introduction: Obstructive sleep apnea (OSA) and loud snoring are conditions with increased cardiovascular risk and notably an association with stroke. Central in stroke are thrombosis and thromboembolism, all related to and initiaing with platelet ac
Externí odkaz:
https://doaj.org/article/1e2a85224f45414f8346fca45a403023
Autor:
Yana Roka-Moiia, Kaitlyn R. Ammann, Samuel Miller-Gutierrez, Jawaad Sheriff, Danny Bluestein, Joseph E. Italiano, Robert C. Flaumenhaft, Marvin J. Slepian
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7386 (2023)
Implantable Cardiovascular Therapeutic Devices (CTD), while lifesaving, impart supraphysiologic shear stress to platelets, resulting in thrombotic and bleeding coagulopathy. We previously demonstrated that shear-mediated platelet dysfunction is assoc
Externí odkaz:
https://doaj.org/article/0b2d22ca8c0d43aea60f04217139354a
Autor:
Anh T. P. Ngo, Jawaad Sheriff, Anne D. Rocheleau, Matthew Bucher, Kendra R. Jones, Anna-Liisa I. Sepp, Lisa E. Malone, Amanda Zigomalas, Alina Maloyan, Wadie F. Bahou, Danny Bluestein, Owen J. T. McCarty, Kristina M. Haley
Publikováno v:
Platelets, Vol 31, Iss 1, Pp 68-78 (2020)
Despite the transient hyporeactivity of neonatal platelets, full-term neonates do not display a bleeding tendency, suggesting potential compensatory mechanisms which allow for balanced and efficient neonatal hemostasis. This study aimed to utilize sm
Externí odkaz:
https://doaj.org/article/97e559c728bf404ea4b49cfaa34390ff
Publikováno v:
Annals of Biomedical Engineering. 51:1094-1105
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c47232bb599927a20c496fac43078a65
https://doi.org/10.1007/s10439-023-03193-2
https://doi.org/10.1007/s10439-023-03193-2
Autor:
Filippo Consolo, Jawaad Sheriff, Silvia Gorla, Nicolò Magri, Danny Bluestein, Federico Pappalardo, Marvin J. Slepian, Gianfranco B. Fiore, Alberto Redaelli
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract We systematically analyzed the relative contributions of frequency component elements of hemodynamic shear stress waveforms encountered in cardiovascular blood recirculating devices as to overall platelet activation over time. We demonstrate
Externí odkaz:
https://doaj.org/article/8bd3bad9a89347f49a85d7408c347b66
Autor:
Marvin J. Slepian, Samuel Miller-Gutierrez, Jawaad Sheriff, Yana Roka-Moiia, Joseph E. Italiano, Daniel E. Palomares, Danny Bluestein
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: Mechanical circulatory support has emerged as lifesaving therapy for patients with advanced heart failure. However, mechanical circulatory support remains limited by a paradoxical coagulopathy accompanied by both thrombosis and bleeding. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a3fb6126ef38486990007c2a3eda1e
https://doi.org/10.1161/atvbaha.120.315583
https://doi.org/10.1161/atvbaha.120.315583
Publikováno v:
Biomech Model Mechanobiol
We developed a multiscale model for simulating aggregation of multiple, free-flowing platelets in low-intermediate shear viscous flow, in which aggregation is mediated by the interaction of α(IIb)β(3) receptors on the platelets membrane and fibrino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0380200a9b3175982defab11702d903
https://doi.org/10.1007/s10237-021-01428-6
https://doi.org/10.1007/s10237-021-01428-6
Autor:
Lisa E. Malone, Danny Bluestein, Cecilia Avila, Jawaad Sheriff, Amanda Zigomalas, Wadie F. Bahou
Publikováno v:
Cell Mol Bioeng
INTRODUCTION: Antiplatelet therapy for neonates and infants is often extrapolated from the adult experience, based on limited observation of agonist-induced neonatal platelet hypoactivity and poor understanding of flow shear-mediated platelet activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac2f7b85296fe7a89d6e5ede6241d22
https://doi.org/10.1007/s12195-020-00628-x
https://doi.org/10.1007/s12195-020-00628-x
Publikováno v:
Cell Mol Bioeng
INTRODUCTION: We developed a multiscale model to simulate the dynamics of platelet aggregation by recruitment of unactivated platelets flowing in viscous shear flows by an activated platelet deposited onto a blood vessel wall. This model uses coarse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b96cd8d9d8707635f9415d7d0488293
https://doi.org/10.1007/s12195-019-00583-2
https://doi.org/10.1007/s12195-019-00583-2