Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Jaw Kang Chang"'
Autor:
Alan Cowan, Jin Jun Luo, Siok L. Dun, Rong-Ming Lyu, Jaw-Kang Chang, Yi-Hung Chen, Nae J. Dun, Ying Zhang
Publikováno v:
Acta Pharmacologica Sinica. 39:770-773
In this brief review we summarize the current fndings relative to the discovery of a small peptide ligand, phoenixin (PNX). Using a bioinformatic approach, two novel peptides PNX-14 and PNX-20 containing 14 and 20 amino acids, respectively, were isol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63eb5da41d3a054efe14b7e648bd0c13
https://doi.org/10.1038/aps.2017.195
https://doi.org/10.1038/aps.2017.195
Publikováno v:
Neuroscience. 310:541-548
Phoenixin (PNX) is a 14-amino acid amidated peptide (PNX-14) or an N-terminal extended 20-residue amidated peptide (PNX-20) recently identified in neural and non-neural tissue. Mass spectrometry analysis identified a major peak corresponding to PNX-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a269a64800587d7a3cbfb584cfcf6a
https://doi.org/10.1016/j.neuroscience.2015.09.055
https://doi.org/10.1016/j.neuroscience.2015.09.055
Autor:
Clemence Blouet, Genevieve Marcelin, Rong-Ming Lyu, Jaw Kang Chang, Nae J. Dun, Young Hwan Jo, Xiaosong Li, Gary J. Schwartz, Streamson C. Chua, Ying Zhang
Publikováno v:
Molecular Metabolism
Tight control of glucose excursions has been a long-standing goal of treatment for patients with type 2 diabetes mellitus in order to ameliorate the morbidity and mortality associated with hyperglycemia. Fibroblast growth factor (FGF) 19 is a hormone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba58d086e2882af27e3e780d1426b1bc
https://doi.org/10.1016/j.molmet.2013.10.002
https://doi.org/10.1016/j.molmet.2013.10.002
Autor:
Gina L. C. Yosten, Nae J. Dun, Aaron J. W. Hsueh, Jaw-Kang Chang, Willis K. Samson, Chloe W. Tullock, Siok L. Dun, Orna Avsian-Kretchmer, Rong-Ming Lyu
Publikováno v:
Journal of Neuroendocrinology. 25:206-215
Normal anterior pituitary function is essential for fertility. Release from the gland of the reproductive hormones luteinising hormone and follicle-stimulating hormone is regulated primarily by hypothalamically-derived gonadotrophin-releasing hormone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::615022401306504200330d8885221933
https://doi.org/10.1111/j.1365-2826.2012.02381.x
https://doi.org/10.1111/j.1365-2826.2012.02381.x
Publikováno v:
Neuroscience. 165:1429-1438
Amylin is a member of calcitonin or calcitonin gene-related peptide (CGRP) family. Immunohistochemical study revealed a dense network of amylin-immunoreactive (irAMY) cell processes in the superficial dorsal horn of the mice. Numerous dorsal root gan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a1f69d52aee876784cfb993719c20b
https://doi.org/10.1016/j.neuroscience.2009.11.063
https://doi.org/10.1016/j.neuroscience.2009.11.063
Autor:
Nae J. Dun, G.C. Brailoiu, J.-G. Li, Jun Yang, Eugen Brailoiu, Jaw-Kang Chang, Xin Gao, Lee-Yuan Liu-Chen, Jin Jun Luo, Siok L. Dun
Publikováno v:
Neuroscience. 159:492-500
With the use of a rabbit polyclonal antiserum against a conserved region (54–118) of C -peptide of human preproinsulin-like peptide 7, referred to herein as C-INSL7, neurons expressing C-INSL7-immunoreactivity (irC-INSL7) were detected in the ponti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::625fa8e7e2d0d68de843acc2ec22ba81
https://doi.org/10.1016/j.neuroscience.2009.01.031
https://doi.org/10.1016/j.neuroscience.2009.01.031
Autor:
Alastair V. Ferguson, Jun Yang, Xiang Qun Chen, Christopher J. Price, Aaron J. W. Hsueh, Yong Xiong Wang, Jaw Kang Chang, Gina L. C. Yosten, Kai Cui, Jian Zhang, Cindy Klein, Orna Avsian-Kretchmer, Willis K. Samson, Xiao-bin Yuan, Rong-Ming Lyu, Ted D. Hoyda
Publikováno v:
Journal of Biological Chemistry. 283:31949-31959
Somatostatin is important in the regulation of diverse neuroendocrine functions. Based on bioinformatic analyses of evolutionarily conserved sequences, we predicted another peptide hormone in pro-somatostatin and named it neuronostatin. Immuno-affini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d319a187c2eb8cd6fb6f6a99f0abb6e8
https://doi.org/10.1074/jbc.m804784200
https://doi.org/10.1074/jbc.m804784200
Autor:
Eugen Brailoiu, Hong Wang, Xiaohua Jiang, Jun Yang, Nae J. Dun, Jaw Kang Chang, G. Cristina Brailoiu
Publikováno v:
Peptides. 29:721-726
Human endothelial cells express urotensin-II (U-II) as well as its receptor GPR14. Using microfluorimetric techniques, the effect of human U-II on cytosolic Ca2+ concentrations [Ca2+]i in cultured human aortic endothelial cells (HAECs) loaded with Fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ad022bb0547e72403aee9b151b40f8
https://doi.org/10.1016/j.peptides.2007.12.019
https://doi.org/10.1016/j.peptides.2007.12.019
Publikováno v:
Neuroscience. 151:701-710
Human immunodeficiency virus 1 (HIV-1) Tat protein is one of the neurotoxins involved in the pathogenesis of HIV-1-associated neuronal disorders. Combined electrophysiological and optical imaging experiments were undertaken to investigate whether HIV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f224c9dc5e04cb1081300526176ca30
https://doi.org/10.1016/j.neuroscience.2007.11.031
https://doi.org/10.1016/j.neuroscience.2007.11.031
Publikováno v:
Journal of Endocrinology. 196:559-564
Obestatin, a product of post-translational processing of the ghrelin prohormone, has been reported to act in the brain to inhibit thirst. We extended our initial studies on water drinking by examining the effects of obestatin on hypovolemia-induced w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7083fc1789f6c6ba50e84c4724b5f2a0
https://doi.org/10.1677/joe-07-0364
https://doi.org/10.1677/joe-07-0364