Fluorescent protein-expressing neural progenitor cells as a tool for transplantation studies.

Autor: Marco Skardelly, Eileen Hempel, Johannes Hirrlinger, Florian Wegner, Jürgen Meixensberger, Javorina Milosevic

Publikováno v: PLoS ONE, Vol 9, Iss 6, p e99819 (2014)

The purpose of this study was to generate quadruple fluorescent protein (QFP) transgenic mice as a source for QFP-expressing neural stem and progenitor cells (NSCs/NPCs) that could be utilized as a tool for transplantation research. When undifferenti

Externí odkaz: https://doaj.org/article/2ec5605e4cd04d0aadc5d4f9b890c13d

Neuroprotective effects of the beta‐catenin stabilization in an oxygen‐ and glucose‐deprived human neural progenitor cell culture system

Autor: Marco Skardelly, Johannes Schwarz, Javorina Milosevic, Khaled Gaber

Publikováno v: International Journal of Developmental Neuroscience. 29:543-547

β-Catenin stabilization achieved either via GSK-3β specific inhibition or involving canonical Wnt signalling pathway, contributes to neuroprotection in an oxygen-glucose deprivation (4h OGD) in vitro hypoxia model performed on human cortical neural

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d9e34e6f81b459a9f8f99c6b89d475
https://doi.org/10.1016/j.ijdevneu.2011.03.010

Labeling of human neural precursor cells using ferromagnetic nanoparticles

Autor: Johanna Scheibe, Sigrid C. Schwarz, Javorina Milosevic, Johannes Schwarz, Almut Focke, Claus Zimmer, Annette Foerschler

Publikováno v: Magnetic Resonance in Medicine. 60:1321-1328

Fetal human neural precursor cells (NPCs) are unique with respect to their capacity to proliferate and to preserve their potential to differentiate into neurons and glia. Human mesencephalic neural precursor cells (hmNPCs) provide a source for dopami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::61b3c9099cf8007fd95ba3c95ce0c122
https://doi.org/10.1002/mrm.21745

Uracil nucleotides stimulate human neural precursor cell proliferation and dopaminergic differentiation: involvement of MEK/ERK signalling

Autor: Herbert Zimmermann, Florian Wegner, Sigrid Schwarz, Ute Roemuss, Javorina Milosevic, Annett Brandt, Johannes Schwarz, Alexander Storch, Antje Arnold

Publikováno v: Journal of Neurochemistry. 99:913-923

Isolation and propagation of neural stem cells derived from human brain tissue uniquely enables the study of human neurogenesis in vitro. In addition, ex vivo-expanded human neural stem/precursor cells (NPCs) may offer novel therapeutic strategies. W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581981ab89d1cd4a197e4a834139269c
https://doi.org/10.1111/j.1471-4159.2006.04132.x

Erythropoietin enhances cell proliferation and survival of human fetal neuronal progenitors in normoxia

Autor: Harald A. Lange, Sebastian Bartel, Javorina Milosevic, Mario Keller, Loredana De Bartolo, Sanja Pavlica, Frank Peinemann, Kai H. Darsow, Augustinus Bader, Mattes Schulze, Antonella Piscioneri

Publikováno v: Brain research 1452 (2012): 18–28. doi:10.1016/j.brainres.2012.02.043
info:cnr-pdr/source/autori:Sanja Pavlicaa; Javorina Milosevic; Mario Keller; Mattes Schulze; Frank Peinemann; Antonella Piscioneri; Loredana De Bartolo; Kai Darsow; Sebastian Bartel; Harald A. Lange; Augustinus Bader/titolo:Erythropoietin enhances cell proliferation and survival of human fetal neuronal progenitors in normoxia/doi:10.1016%2Fj.brainres.2012.02.043/rivista:Brain research/anno:2012/pagina_da:18/pagina_a:28/intervallo_pagine:18–28/volume:1452

Extensive data reporting the neurogenerative, neuroprotective and neuroregenerative potential of erythropoietin (EPO), mainly on RNA level, can be found in the literature. However, there is still a poor knowledge on the response of neuronal progenito

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b0271abedb88fe3c1266ed0f4df2d5c