Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Javiera Villar"'
Autor:
Haiyin Liu, Kayla R. Wilson, Ashley M. Firth, Christophe Macri, Patrick Schriek, Annabelle B. Blum, Javiera Villar, Samuel Wormald, Mitch Shambrook, Bangyan Xu, Hui Jing Lim, Hamish E. G. McWilliam, Andrew F. Hill, Laura E. Edgington-Mitchell, Irina Caminschi, Mireille H. Lahoud, Elodie Segura, Marco J. Herold, Jose A. Villadangos, Justine D. Mintern
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Regulated trafficking of major histocompatibility complex class II and CD86 is a prerequisite of antigen presenting cell functionality. Authors show here that ubiquitin-like protein 3 is critically involved in the ubiquitination process that controls
Externí odkaz:
https://doaj.org/article/e0c1150585254283885c639c972afad3
Autor:
José M. Jiménez, Michelle L. Salazar, Sergio Arancibia, Javiera Villar, Fabián Salazar, Gordon D. Brown, Ed C. Lavelle, Luisa Martínez-Pomares, Jafet Ortiz-Quintero, Sergio Lavandero, Augusto Manubens, María Inés Becker
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Mollusk hemocyanins have biomedical uses as carriers/adjuvants and nonspecific immunostimulants with beneficial clinical outcomes by triggering the production of proinflammatory cytokines in antigen-presenting cells (APCs) and driving immune response
Externí odkaz:
https://doaj.org/article/09a1af432b354c879d5b0d1dee5c709b
Autor:
Juan José Mora Román, Miguel Del Campo, Javiera Villar, Francesca Paolini, Gianfranca Curzio, Aldo Venuti, Lilian Jara, Jorge Ferreira, Paola Murgas, Alvaro Lladser, Augusto Manubens, María Inés Becker
Publikováno v:
Journal of Immunology Research, Vol 2019 (2019)
Mollusk hemocyanins have been used for decades in immunological and clinical applications as natural, nontoxic, nonpathogenic, and nonspecific immunostimulants for the treatment of superficial bladder cancer, as carriers/adjuvants of tumor-associated
Externí odkaz:
https://doaj.org/article/ebf5bd48278b445bbdea1c847ec62564
Autor:
Lamine Alaoui, Javiera Villar, Renaud Leclere, Simon Le Gallou, Francis Relouzat, Henri-Alexandre Michaud, Karin Tarte, Natacha Teissier, Benoît Favier, Mikaël Roussel, Elodie Segura
Publikováno v:
Journal of Experimental Medicine
Journal of Experimental Medicine, 2023, 220 (7), pp.e20230002. ⟨10.1084/jem.20230002⟩
Journal of Experimental Medicine, 2023, 220 (7), pp.e20230002. ⟨10.1084/jem.20230002⟩
International audience; Macrophages play a central role in tissue homeostasis and host defense. However, the properties of human macrophages in non-diseased tissues remain poorly understood. Here, we characterized human tonsil macrophages and identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443a94292a6e3533defbd80f42ce9af2
https://hal.science/hal-04090249
https://hal.science/hal-04090249
Autor:
Javiera Villar, Adeline Cros, Alba De Juan, Lamine Alaoui, Pierre-Emmanuel Bonte, Colleen M. Lau, Ioanna Tiniakou, Boris Reizis, Elodie Segura
Publikováno v:
Nature Immunology
Nature Immunology, 2023, 24 (1), pp.84-95. ⟨10.1038/s41590-022-01374-0⟩
Nature Immunology, 2023, 24 (1), pp.84-95. ⟨10.1038/s41590-022-01374-0⟩
In inflamed tissues, monocytes differentiate into macrophages (mo-Macs) or dendritic cells (mo-DCs). In chronic nonresolving inflammation, mo-DCs are major drivers of pathogenic events. Manipulating monocyte differentiation would therefore be an attr
Publikováno v:
EMBO reports.
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629376
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abf90b94c3bf4432cb0e7b29c76e14b6
https://doi.org/10.1007/978-1-0716-2938-3_11
https://doi.org/10.1007/978-1-0716-2938-3_11
Autor:
Maira Rivera, Javiera Villar, Mauricio Baez, José M. Jiménez, Michelle L. Salazar, María Inés Becker, Augusto Manubens
Publikováno v:
The Journal of Biological Chemistry
Hemocyanins are widely used as carriers, adjuvants, and nonspecific immunostimulants in cancer because they promote Th1 immunity in mammals. Hemocyanins also interact with glycan-recognizing innate immune receptors on antigen-presenting cells, such a
Autor:
Gianfranca Curzio, Lilian Jara, Javiera Villar, Augusto Manubens, Aldo Venuti, María Inés Becker, Alvaro Lladser, Juan José Mora Román, Paola Murgas, Miguel Del Campo, Francesca Paolini, Jorge Ferreira
Publikováno v:
Journal of Immunology Research, Vol 2019 (2019)
Journal of Immunology Research
Journal of Immunology Research
Mollusk hemocyanins have been used for decades in immunological and clinical applications as natural, nontoxic, nonpathogenic, and nonspecific immunostimulants for the treatment of superficial bladder cancer, as carriers/adjuvants of tumor-associated
Autor:
María Inés Becker, Michelle L Salazar, Diego Díaz-Dinamarca, Abel E Vásquez, Javiera Villar, Alejandra Alvarado, Byron Castillo, Daniel Navarro, Fabián Salazar, Augusto Manubens
Publikováno v:
The Journal of Immunology. 208:102.26-102.26
Hemocyanins are oligomeric glycoproteins widely used as immunomodulators because they bias immunity towards a Th1 profile when inoculated in mammals. We have demonstrated that hemocyanins are internalized through receptor-mediated endocytosis, and TL