Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Javier Vega Ramos"'
Autor:
Mitra Ashayeripanah, Javier Vega-Ramos, Daniel Fernandez-Ruiz, Shirin Valikhani, Aaron T.L. Lun, Jason T. White, Louise J. Young, Atefeh Yaftiyan, Yifan Zhan, Linda Wakim, Irina Caminschi, Mireille H. Lahoud, Andrew M. Lew, Ken Shortman, Gordon K. Smyth, William R. Heath, Justine D. Mintern, Antoine Roquilly, Jose A. Villadangos
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113754- (2024)
Summary: Blood-borne pathogens can cause systemic inflammatory response syndrome (SIRS) followed by protracted, potentially lethal immunosuppression. The mechanisms responsible for impaired immunity post-SIRS remain unclear. We show that SIRS trigger
Externí odkaz:
https://doaj.org/article/531a91054c1e4bb68aeda10b35050804
Autor:
Elisenda Alari-Pahissa, Laura Notario, Elena Lorente, Javier Vega-Ramos, Ana Justel, Daniel López, José A Villadangos, Pilar Lauzurica
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48593 (2012)
CD69 is rapidly upregulated on T cells upon activation. In this work we show that this is also the case for CD69 expression on dendritic cells (DC). Thus, the expression kinetics of CD69 on both cell types is reminiscent of the one of costimulatory m
Externí odkaz:
https://doaj.org/article/8e6badfb08c642c28f59673a03a449c5
Autor:
Jose A Villadangos, Wolfgang Weninger, Alexandra Rizzitelli, L.T. Joeckel, Javier Vega-Ramos, Matthew Mangan, Dion Kaiserman, Phillip I. Bird, Andrew J. Mitchell, Ben Roediger
Publikováno v:
Molecular Immunology. 82:50-56
Serpinb9 (Sb9, also called Spi6) is an intracellular inhibitor of granzyme B (grB) that protects cytotoxic lymphocytes from grB-mediated death. In addition, Sb9 is also expressed in accessory immune cells, including dendritic cells (DCs), although it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80883229f18f59875b5eb3738c56933b
https://doi.org/10.1016/j.molimm.2016.12.011
https://doi.org/10.1016/j.molimm.2016.12.011
Autor:
Zhongfang Wang, Javier Vega Ramos, David C. Jackson, Katherine Kedzierska, Brendon Y. Chua, Lorena E. Brown, Emily J. Fairmaid, Sergio M. Quiñones Parra
Publikováno v:
Vaccine. 33:5148-5154
The emergence of the avian-origin influenza H7N9 virus and its pandemic potential has highlighted the ever-present need to develop vaccination approaches to induce cross-protective immunity. In this study, we examined the establishment of cross-react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a220d5969fe464dd94df0613d2c7555c
https://doi.org/10.1016/j.vaccine.2015.08.001
https://doi.org/10.1016/j.vaccine.2015.08.001
Autor:
Irina Caminschi, Scott E. Panozza, Jessica Li, Angus P. R. Johnston, Claire Dumont, Christophe Macri, Haiyin Liu, Nishma Gupta, Jose A Villadangos, Justine D. Mintern, Anika Reuter, Javier Vega-Ramos, Elodie Segura
Publikováno v:
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2015, 194 (6), pp.2696-2705. ⟨10.4049/jimmunol.1402535⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2015, 194 (6), pp.2696-2705. ⟨10.4049/jimmunol.1402535⟩
Ab-targeted vaccination involves targeting a receptor of choice expressed by dendritic cells (DCs) with Ag-coupled Abs. Currently, there is little consensus as to which criteria determine receptor selection to ensure superior Ag presentation and immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d5180d281292cc3603147f59c6981c6
https://doi.org/10.4049/jimmunol.1402535
https://doi.org/10.4049/jimmunol.1402535
Publikováno v:
Journal of Biological Chemistry. 289:9730-9740
The cysteine protease inhibitor cystatin C is thought to be secreted by most cells and eliminated in the kidneys, so its concentration in plasma is diagnostic of kidney function. Low extracellular cystatin C is linked to pathologic protease activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14bc3f5eb1b09512639823d0054354f5
https://doi.org/10.1074/jbc.m113.538041
https://doi.org/10.1074/jbc.m113.538041
Autor:
Michael Inouye, Scott N. Mueller, Nicholas Collins, Pilar Lauzurica, Tijana Stefanovic, David C. Tscharke, Javier Vega-Ramos, William R. Heath, Ming-Li Hafon, Thomas Gebhardt, Francis R. Carbone, Laura K. Mackay, Joel Z. Ma, Azad Rahimpour, Angus T. Stock
Publikováno v:
Nature Immunology. 14:1294-1301
Tissue-resident memory T cells (T(RM) cells) provide superior protection against infection in extralymphoid tissues. Here we found that CD103(+)CD8(+) T(RM) cells developed in the skin from epithelium-infiltrating precursor cells that lacked expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef257d64524d524edae86727c691624
https://doi.org/10.1038/ni.2744
https://doi.org/10.1038/ni.2744
Autor:
Jose A Villadangos, Javier Vega-Ramos
Publikováno v:
Molecular Immunology. 55:175-178
The antigen presentation properties of Dendritic cells (DC) are key factors in the initiation and modulation of immune responses. The mechanisms involved in the regulation of MHC II antigen presentation in DC have been thoroughly investigated. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c581acbe51eb05ab2931f103ae4a7f32
https://doi.org/10.1016/j.molimm.2012.10.034
https://doi.org/10.1016/j.molimm.2012.10.034
Autor:
Jose A Villadangos, Janet L. Wee, Po Ki Ho, G. J. Hämmerling, Jessica Blakeley, Annemiek B. van Spriel, Maria C. Demaria, Javier Vega-Ramos, Mark D. Wright, Michael J. Hickey, Eleanor L. Jones
Publikováno v:
Journal of Immunology, 196, 3, pp. 978-987
Journal of Immunology, 196, 978-987
Journal of Immunology, 196, 978-987
Contains fulltext : 172274.pdf (Publisher’s version ) (Closed access) This study supports a new concept where the opposing functions of the tetraspanins CD37 and CD82 may coordinate changes in migration and Ag presentation during dendritic cell (DC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7aa1adb4590b27f60a861888e8e43fb
https://hdl.handle.net/2066/172274
https://hdl.handle.net/2066/172274
Autor:
Andrew M. Lew, Javier Vega-Ramos, Jose A Villadangos, Yifan Zhan, Yuekang Xu, Emma M. Carrington
Publikováno v:
European Journal of Immunology. 42:2889-2900
Fms-like tyrosine kinase 3 ligand (Flt3L) is a major cytokine that drives development of dendritic cells (DCs) under steady state, whereas GM-CSF becomes a prominent influence on differentiation during inflammation. The influence GM-CSF exerts on Flt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d20f65e4f1668bc8ed51c396745adbf7
https://doi.org/10.1002/eji.201242477
https://doi.org/10.1002/eji.201242477