Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Javier Suela"'
Autor:
David Rubio-Mangas, Mariano García-Arranz, Yaima Torres-Rodriguez, Miguel León-Arellano, Javier Suela, Damián García-Olmo
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Differential presence of exons (DPE) by next generation sequencing (NGS) is a method of interpretation of whole exome sequencing. This method has been proposed to design a predictive and diagnostic algorithm with clinical value in plasma fro
Externí odkaz:
https://doaj.org/article/5581e58559bb4786b55071852735405c
Autor:
Sara Alvarez, Javier Suela, Ana Valencia, Agustín Fernández, Mark Wunderlich, Xabier Agirre, Felipe Prósper, José Ignacio Martín-Subero, Alba Maiques, Francesco Acquadro, Sandra Rodriguez Perales, María José Calasanz, Jose Roman-Gómez, Reiner Siebert, James C Mulloy, José Cervera, Miguel Angel Sanz, Manel Esteller, Juan C Cigudosa
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12197 (2010)
Aberrant promoter DNA methylation has been shown to play a role in acute myeloid leukemia (AML) pathophysiology. However, further studies to discuss the prognostic value and the relationship of the epigenetic signatures with defined genomic rearrange
Externí odkaz:
https://doaj.org/article/918841f8100945f982ac9470a6b6b0c6
Autor:
Jose I Martin-Subero, Ole Ammerpohl, Marina Bibikova, Eliza Wickham-Garcia, Xabier Agirre, Sara Alvarez, Monika Brüggemann, Stefanie Bug, Maria J Calasanz, Martina Deckert, Martin Dreyling, Ming Q Du, Jan Dürig, Martin J S Dyer, Jian-Bing Fan, Stefan Gesk, Martin-Leo Hansmann, Lana Harder, Sylvia Hartmann, Wolfram Klapper, Ralf Küppers, Manuel Montesinos-Rongen, Inga Nagel, Christiane Pott, Julia Richter, José Román-Gómez, Marc Seifert, Harald Stein, Javier Suela, Lorenz Trümper, Inga Vater, Felipe Prosper, Claudia Haferlach, Juan Cruz Cigudosa, Reiner Siebert
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e6986 (2009)
Alterations in the DNA methylation pattern are a hallmark of leukemias and lymphomas. However, most epigenetic studies in hematologic neoplasms (HNs) have focused either on the analysis of few candidate genes or many genes and few HN entities, and co
Externí odkaz:
https://doaj.org/article/245b34fbecf54135b42985c0a2339f84
Autor:
Bibiana I. Ferreira, Juan F. García, Javier Suela, Manuela Mollejo, Francisca I. Camacho, Angel Carro, Santiago Montes, Miguel A. Piris, Juan C. Cigudosa
Publikováno v:
Haematologica, Vol 93, Iss 5 (2008)
Background Low-grade B-cell lymphomas are a very heterogeneous group of tumors, whose differential diagnosis is frequently compromised by the lack of specific cytogenetic or molecular features. Our objective was to search for genomic features that al
Externí odkaz:
https://doaj.org/article/e0660c276b284032a7583df07b80feed
Autor:
Cristina Largo, Borja Saéz, Sara Alvarez, Javier Suela, Bibiana Ferreira, David Blesa, Felipe Prosper, M. Jose Calasanz, Juan C. Cigudosa
Publikováno v:
Haematologica, Vol 92, Iss 6 (2007)
Background and Objectives Multiple myeloma (MM) is a malignant plasma cell neoplasia in which genetic studies have shown that genomic changes may affect almost all chromosomes, as shown by fluorescence in situ hybridization (FISH) and comparative gen
Externí odkaz:
https://doaj.org/article/fe18bb5eaa0e4371bc2d4dd7aeed1cd0
Publikováno v:
Oncoscience. 10:4-5
Autor:
Inmaculada Martín, Javier García-Planells, Javier Suela, Eva Barrenechea, M. M. Gil, Belén Prieto, Belén Santacruz, Concepción González, Begoña Adiego
Publikováno v:
Advances in Laboratory Medicine, Vol 1, Iss 3, Pp 669-81 (2020)
Scopus
Scopus
In this paper, the scientific societies SEGO, SEQCML and AEDP provide a series of consensus-based recommendations for prenatal screening and diagnosis of genetic abnormalities. A set of evaluation indicators are also proposed as a means to improve th
Autor:
Eva Barrenechea, M. M. Gil, Begoña Adiego, Belén Santacruz, Javier García-Planells, Javier Suela, Belén Prieto-García, Inmaculada Martín, Concepción González
Publikováno v:
Advances in Laboratory Medicine, Vol 1, Iss 3, Pp 669-81 (2020)
Resumen El objetivo de este trabajo es difundir las recomendaciones del consenso entre las sociedades científicas SEGO, SEQCML y AEDP sobre cribado y diagnóstico prenatal de anomalías genéticas, así como una propuesta de indicadores de evaluaci
Autor:
Enrique Samper, Yaima Torres, Antonio de Molina, Rosa María Carmona, Luis Blanco, Javier Suela, Antonio Bernad, Diego Herrero, Susana Cañón, Beatriz Escudero
Publikováno v:
DNA Repair. 54:40-45
Non-homologous end joining (NHEJ) is the main mechanism for double strand break (DSB) DNA repair. The error-prone DNA polymerase mu (Polμ) is involved in immunoglobulin variable region rearrangement and in general, NHEJ in non-lymphoid cells. Deleti
Autor:
Ye Yin, Jeremy Cao, Tao Duan, Shushu Fan, Jia Li, Jinman Zhang, Janez Bernik, Jianyu Zhu, Weiqiang Liu, Pi-Lin Sung, Qiang Zhao, Mohammad Reza Hekmat, Luming Sun, Ka Yiu Yuen, Yingwei Chen, Tao Ma, Nien-Tzu Liu, F. J. Pérez Ruiz, Yaima Torres, Shujia Huang, Min Chen, Zhihua Li, Li Shen, Nataša Tul, Eva Traven, Monica D. Garcia, Yafeng Zhou, Qiong Pan, Yuying Yuan, Xin Jin, Yonghua Huang, Masoud Garshasbi, Suihua Feng, Huanming Yang, Xing Ji, Baosheng Zhu, Mao Mao, Yuan Han, Jingsi Chen, Steve Tong, Mahesh Choolani, Wen Yuan, Irene Wing Shan Chik, Siyuan Lin, Ching-Fong Tseng, Zhiyuan Shan, Javier Suela, Hong Yao, Haitao Wu, So Hin Cheng, Jian Wang, Li Zeng, Qiang Liu, Uršula Reš, Fang Chen, Wenyan Li, Yuying Wang, Mengyao Dai, Cheng Fan, Jia Ju, Laura Lyman Rodriguez, Yan Chen, Depeng Zhao, Juan C. Cigudosa
Publikováno v:
Genetics in medicine : official journal of the American College of Medical Genetics. 21(10)
Multiple chromosomal aneuploidies may be associated with maternal malignancies and can cause failure of noninvasive prenatal screening (NIPS) tests. However, multiple chromosomal aneuploidies show poor specificity and selectivity for diagnosing mater