Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Javier Sierra-Pagan"'
Autor:
Satyabrata Das, Javier Sierra-Pagan, Wuming Gong, Nikita Dsouza, Thijs Larson, Mary G Garry, Edgar Luzete-Monteiro, Kenneth S Zaret, Daniel J Garry
Publikováno v:
Circulation Research. 131
The vasculature is an essential organ for the delivery of blood and oxygen to all tissues of the body and thus relevant to the treatment of ischemic heart disease. The ETS-related transcription factor 2 (ETV2) is a transcription factor that is both n
Autor:
Joshua W.M. Theisen, Javier Sierra-Pagan, Bhairab N. Singh, Daniel J. Garry, Wuming Gong, Erik Skie, Mary G. Garry, Satyabrata Das
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 40:2875-2890
Objective: Endothelial progenitors migrate early during embryogenesis to form the primary vascular plexus. The regulatory mechanisms that govern their migration are not completely defined. Here, we describe a novel role for ETV2 (Ets variant transcri
Autor:
Javier Sierra-Pagan, Nikita Dsouza, Thijs A Larson, Satyabrata Das, Patricia Stan, Wuming Gong, Mary G Garry, Daniel J Garry
Publikováno v:
Circulation. 144
Background: Congenital heart disease (CHD) is the most common genetic birth defect and has considerable morbidity and mortality. Therefore, it is essential to define the mechanisms governing the specification and differentiation of mesodermal and car
Autor:
Mary G. Garry, Vinayak Gupta, Satyabrata Das, Javier Sierra-Pagan, Daniel J. Garry, Wuming Gong, Erik Skie
Publikováno v:
Circulation Research. 129
Background: Ets transcription factors function as important developmental regulators and are known to be modulators of cell fate. Previously, in conjunction with co-factors, we have described Ets variant 2 (Etv2) as an essential regulator of the hema
Autor:
Daniel J. Garry, Bhairab N. Singh, Mary G. Garry, Demetris Yannopoulos, Joshua W.M. Theisen, Wuming Gong, Javier Sierra-Pagan, Pruthvi Shah, Satyabrata Das, Erik Skie
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Etv2, an Ets-transcription factor, governs the specification of the earliest hemato-endothelial progenitors during embryogenesis. While the transcriptional networks during hemato-endothelial development have been well described, the mechanistic detai
Autor:
Satyabrata Das, Wuming Gong, Erik Skie, Daniel J. Garry, Javier Sierra-Pagan, Mary G. Garry, Bhairab N. Singh
Publikováno v:
Circulation. 142
Background: Endothelial progenitors migrate early during embryogenesis to form the primary vascular plexus. ETV2, an Ets-transcription factor, governs the specification of the earliest hemato-endothelial progenitors during embryogenesis. The regulato
Publikováno v:
Circulation. 142
Background: Genetic mutations perturb the multipotent progenitors, which results in congenital cardiovascular disease. Therefore, it is essential to decipher the pioneer factors and the regulatory pathways that govern the specification and differenti
Autor:
Javier Sierra-Pagan, Joshua W.M. Theisen, Wuming Gong, Pruthvi Shah, Demetris Yannopoulos, Satyabrata Das, Bhairab N. Singh, Daniel J. Garry, Erik Skie, Mary G. Garry
Publikováno v:
Circulation Research. 125
Etv2, an Ets-transcription factor, governs the specification of the earliest hemato-endothelial progenitors during embryogenesis. While the transcriptional networks during hemato-endothelial development have been well described, the mechanistic detai