Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Javier Santos-Aberturas"'
Publikováno v:
Plant-Environment Interactions, Vol 3, Iss 1, Pp 10-15 (2022)
Abstract Stress memory is a phenomenon whereby exposure to initial stress event influences a response to subsequent stress exposures. Studying stress memory is important to understand the cellular behavior in dynamic environment, especially nowadays,
Externí odkaz:
https://doaj.org/article/872722a163354de08c86f105a8710d79
Publikováno v:
Antibiotics, Vol 11, Iss 2, p 195 (2022)
Bacterial secondary metabolites represent an invaluable source of bioactive molecules for the pharmaceutical and agrochemical industries. Although screening campaigns for the discovery of new compounds have traditionally been strongly biased towards
Externí odkaz:
https://doaj.org/article/5a7746d73d4a45dbb5bc4300cb753e9c
Autor:
Franziska Leipoldt, Javier Santos-Aberturas, Dennis P. Stegmann, Felix Wolf, Andreas Kulik, Rodney Lacret, Désirée Popadić, Daniela Keinhörster, Norbert Kirchner, Paulina Bekiesch, Harald Gross, Andrew W. Truman, Leonard Kaysser
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Metalloproteinase inhibitors are leads for drug development, but their biosynthetic pathways are often unknown. Here the authors show that the acyl branched warhead of actinonin and matlystatins derives from an ethylmalonyl-CoA-like pathway and the s
Externí odkaz:
https://doaj.org/article/33d55bdb2e15447e910a355a7a9c3566
Autor:
Yolanda Martínez-Burgo, Javier Santos-Aberturas, Antonio Rodríguez-García, Eva G. Barreales, José Rubén Tormo, Andrew W. Truman, Fernando Reyes, Jesús F. Aparicio, Paloma Liras
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Expression of non-native transcriptional activators may be a powerful general method to activate secondary metabolites biosynthetic pathways. PAS-LuxR regulators, whose archetype is PimM, activate the biosynthesis of polyene macrolide antifungals and
Externí odkaz:
https://doaj.org/article/d6b30479f65e4da7b83c3debf9d3b47b
Autor:
Javier Santos-Aberturas, Cláudia M Vicente, Tamara D Payero, Lara Martín-Sánchez, Carmen Cañibano, Juan F Martín, Jesús F Aparicio
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38536 (2012)
Control of polyene macrolide production in Streptomyces natalensis is mediated by the transcriptional activator PimR. This regulator combines an N-terminal domain corresponding to the Streptomyces antibiotic regulatory protein (SARP) family of transc
Externí odkaz:
https://doaj.org/article/d6846085a137452284e13b06761630f0
Autor:
Susana M Guerra, Antonio Rodríguez-García, Javier Santos-Aberturas, Cláudia M Vicente, Tamara D Payero, Juan F Martín, Jesús F Aparicio
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31475 (2012)
LAL regulators (Large ATP-binding regulators of the LuxR family) constitute a poorly studied family of transcriptional regulators. Several regulators of this class have been identified in antibiotic and other secondary metabolite gene clusters from a
Externí odkaz:
https://doaj.org/article/4bd683e9d3384f87b506d839945a860a
Autor:
Javier Santos-Aberturas, Natalia Vior
Publikováno v:
Antibiotics (Basel, Switzerland). 11(2)
Bacterial secondary metabolites represent an invaluable source of bioactive molecules for the pharmaceutical and agrochemical industries. Although screening campaigns for the discovery of new compounds have traditionally been strongly biased towards
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2296
SummaryStress memory is a phenomenon whereby exposure to initial stress event influences a response to subsequent stress exposures. Studying stress memory is important to understand the cellular behaviour in dynamic environment, especially nowadays,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d24e9dbc1ba46248a035864b588e792e
https://doi.org/10.1101/2021.07.23.453471
https://doi.org/10.1101/2021.07.23.453471
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2296
In recent years, genome mining has become a powerful strategy for the discovery of new specialized metabolites from microorganisms. However, the discovery of new groups of ribosomally synthesized and post-translationally modified peptides (RiPPs) by