Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Javier S. Castresana"'
Publikováno v:
Journal of Clinical and Translational Science, Vol 8 (2024)
Adenylate kinases (AKs) are important enzymes involved in cellular energy metabolism. Among AKs, AK5 (adenylate kinase 5), a cytosolic protein, is emerging as a significant contributor to various diseases and cellular processes. This comprehensive re
Externí odkaz:
https://doaj.org/article/32b82a76f8414860bae6212d5ae332ab
Publikováno v:
Cells, Vol 13, Iss 7, p 617 (2024)
Glioblastoma is the most aggressive, malignant, and lethal brain tumor of the central nervous system. Its poor prognosis lies in its inefficient response to currently available treatments that consist of surgical resection, radiotherapy, and chemothe
Externí odkaz:
https://doaj.org/article/1d4a135499924c42a9df6e46e67b7975
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/6d72348f828d4051b2f22000e3797a68
Autor:
Javier S. Castresana, Bárbara Meléndez
Publikováno v:
Cells, Vol 12, Iss 16, p 2063 (2023)
Glioblastoma is the most aggressive intracranial tumor [...]
Externí odkaz:
https://doaj.org/article/0a68b22a29884cae8065963b3b9ac043
Publikováno v:
Cells, Vol 12, Iss 12, p 1578 (2023)
Glioblastoma is the most aggressive form of brain tumor originating from glial cells with a maximum life expectancy of 14.6 months. Despite the establishment of multiple promising therapies, the clinical outcome of glioblastoma patients is abysmal. D
Externí odkaz:
https://doaj.org/article/87dc65131cdb45e4ab6993db75e40bd9
Autor:
Noela Rodríguez-Losada, Javier de la Rosa, María Larriva, Rune Wendelbo, José A. Aguirre, Javier S. Castresana, Santiago J. Ballaz
Publikováno v:
Journal of Advanced Research, Vol 23, Iss , Pp 37-45 (2020)
Alpha-Synuclein (aSyn) is a chameleon-like protein. Its overexpression and intracellular deposition defines neurodegenerative α-synucleinopathies including Parkinson’s disease. Whether aSyn up-regulation is the cause or the protective reaction to
Externí odkaz:
https://doaj.org/article/928e5f1f85e44a489e810c3e2e5eb221
Publikováno v:
Cells, Vol 11, Iss 14, p 2130 (2022)
Central nervous system tumors are a leading cause of cancer-related death in children and adults, with medulloblastoma (MB) and glioblastoma (GBM) being the most prevalent malignant brain tumors, respectively. Despite tremendous breakthroughs in neur
Externí odkaz:
https://doaj.org/article/a5db6e363c0641378c50cd00b2c49f87
Publikováno v:
Pharmaceuticals, Vol 14, Iss 11, p 1184 (2021)
Neuroblastoma is the most frequent malignant extracranial solid tumor of infancy. The overall objective of this work consists of determining the presence of alterations in the p53/MDM2/p14ARF signaling pathway in neuroblastoma cell lines and decipher
Externí odkaz:
https://doaj.org/article/6950787a05a7476b91ba394d33fd172f
Autor:
Javier S. Castresana, Bárbara Meléndez
Publikováno v:
Cells, Vol 10, Iss 6, p 1456 (2021)
Glioblastoma is the most malignant primary brain tumor [...]
Externí odkaz:
https://doaj.org/article/9267a0eb4f6a4fbf93c317be2bdfb265
Autor:
Alejandro Urdiciain, Elena Erausquin, María V. Zelaya, Idoya Zazpe, José L. Lanciego, Bárbara Meléndez, Juan A. Rey, Miguel A. Idoate, Natalia A. Riobo-Del Galdo, Javier S. Castresana
Publikováno v:
Biology, Vol 10, Iss 6, p 467 (2021)
Glioblastoma multiforme, the most common type of malignant brain tumor as well as the most aggressive one, lacks an effective therapy. Glioblastoma presents overexpression of mesenchymal markers Snail, Slug, and N-Cadherin and of the autophagic marke
Externí odkaz:
https://doaj.org/article/bdc0fba0691247a994f9dd392c66f8c4