Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Javier R. Jaldin-Fincati"'
Autor:
Victoria L. Tokarz, Rafaela V. S. Pereira, Javier R. Jaldin-Fincati, Sivakami Mylvaganam, Amira Klip
Publikováno v:
Molecular Biology of the Cell. 34
Obesity impairs lymphatic function, but the contribution of lymphatic endothelial cells to metabolic disease phenotypes is poorly understood. It is shown that the saturated fatty acid palmitate, but not the unsaturated fatty acid palmitoleate, causes
Autor:
Javier R. Jaldin‐Fincati, Serene Moussaoui, Maria Cecilia Gimenez, Cheuk Y. Ho, Charlene E. Lancaster, Roberto J. Botelho, Salvador F. Ausar, Roger H. Brookes, Mauricio R. Terebiznik
Publikováno v:
Molecular Microbiology. 117:1173-1195
Aluminum salts have been successfully utilized as adjuvants to enhance the immunogenicity of vaccine antigens since the 1930s. However, the cellular mechanisms behind the immune adjuvanticity effect of these materials in antigen-presenting cells are
Autor:
Samaneh Yazdani, Philip J. Bilan, Javier R. Jaldin-Fincati, Janice Pang, Felicia Ceban, Ekambir Saran, John H. Brumell, Spencer A. Freeman, Amira Klip
Publikováno v:
Molecular biology of the cell. 33(12)
We followed radioactive and fluorescent glucose derivatives in human microvascular endothelial cells (HAMEC). [3H]-2-DG entered via GLUT1/3 and 20% incorporated into glycogen. Glycogenolysis and 2-DG-6-phosphate provided glucose that exited cells via
Autor:
Nicolás M. Díaz, Javier R. Jaldin-Fincati, María C. Sánchez, Gustavo A. Chiabrando, Virginia Actis Dato, Pablo F. Barcelona
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Activated α2-macroglobulin (α2M*) and its receptor, low-density lipoprotein receptor-related protein 1 (LRP1), have been linked to proliferative retinal diseases. In Müller glial cells (MGCs), the α2M*/LRP1 interaction induces cell signaling, cel
Publikováno v:
The FASEB Journal. 33
Publikováno v:
Traffic (Copenhagen, Denmark). 20(6)
An endothelial cell monolayer separates interstitia from blood and lymph, and determines the bidirectional transfer of solutes and macromolecules across these biological spaces. We review advances in transport modalities across these endothelial barr
A complex of Rab13 with MICAL-L2 and α-actinin-4 is essential for insulin-dependent GLUT4 exocytosis
Publikováno v:
Molecular Biology of the Cell
Rab13 is necessary for insulin-regulated GLUT4-vesicle exocytosis in muscle. Biochemical and imaging analyses provide evidence that activated Rab13 engages a scaffold protein MICAL-L2 to form a complex with Rab13 and α-actinin-4. Through GLUT4 inter
Publikováno v:
The FASEB Journal. 32
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 315(2)
Whereas the blood microvasculature constitutes a biological barrier to the action of blood-borne insulin on target tissues, the lymphatic microvasculature might act as a barrier to subcutaneously administrated insulin reaching the circulation. Here,