Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Javier Pedreño"'
Autor:
Oriol Bosch-Sanz, Yvette Rabadà, Xevi Biarnés, Javier Pedreño, Luis Caveda, Mercedes Balcells, Jordi Martorell, David Sánchez-García
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 14942
Fibrinolysis is a natural process that ensures blood fluidity through the removal of fibrin deposits. However, excessive fibrinolytic activity can lead to complications in different circumstances, such as general surgery or severe trauma. The current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e18250a1521d83df79796143696594f9
https://pubmed.ncbi.nlm.nih.gov/36499270
https://pubmed.ncbi.nlm.nih.gov/36499270
Autor:
Xavier Biarnés Fontal, Noemí Balà Palasí, David Sánchez García, Mercedes Balcells Camps, Jordi Martorell López, Francisco Javier Pedreño Egea, Oriol Bosch Sanz
Publikováno v:
The 2nd Molecules Medicinal Chemistry Symposium (MMCS): Facing Novel Challenges in Drug Discovery.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53fde6877b34c4cf995b32c8aebf27d2
https://doi.org/10.3390/proceedings2019022106
https://doi.org/10.3390/proceedings2019022106
Publikováno v:
Atherosclerosis. 155:99-112
We present evidence of a link between low-density lipoprotein (LDL) receptor binding and activation of a platelet G-coupled protein. LDL stimulation induced cytosolic [Ca 2+ ] i mobilization, increase in inositol 1,4,5-triphosphate (IP 3 ) formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8ea1e455e1a1592b9492c5c25418e6d
https://doi.org/10.1016/s0021-9150(00)00545-1
https://doi.org/10.1016/s0021-9150(00)00545-1
Autor:
Javier Pedreño, Silvia Paredes, Germán Camejo, Eva Hurt-Camejo, Lluís Masana, Pere Benito, Joan-Carles Vallvé, Birgitta Rosengren, Peter Sartipy, Olov Wiklund
Publikováno v:
Arthritis & Rheumatism. 44:2761-2767
Objective. This work studied the presence of inflammatory and atherogenic lipoprotein markers that could explain the high incidence of cardiovascular disease (CVD) reported in rheumatoid arthritis (RA) patients. Methods. Inflammatory markers were 1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4785c3fcdaacaeee5cff2b5263449c9
https://doi.org/10.1002/1529-0131(200112)44:12<2761::aid-art463>3.0.co
https://doi.org/10.1002/1529-0131(200112)44:12<2761::aid-art463>3.0.co
Publikováno v:
Atherosclerosis. 154:23-29
Early studies considered that fibrinogen receptor (glycoprotein [GP] IIb–IIIa or platelet integrin α IIb β 3 ) is the binding site for low-density lipoprotein (LDL) and high-density lipoprotein type 3 (HDL 3 ). Recent data, however, do not suppor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71ac2677461a6c0e46c4ae12a12a21f4
https://doi.org/10.1016/s0021-9150(00)00442-1
https://doi.org/10.1016/s0021-9150(00)00442-1
Autor:
Agustı́ Jornet, Jaume Canela, Alfons Ballester, Mariano Uson, Javier Pedreño, Rosa Fernández, Marius Petit
Publikováno v:
International Journal of Cardiology. 74:159-167
Multiple studies have demonstrated that elevated serum lipoprotein (a) [Lp(a)] levels are independent predictors for coronary artery disease (CAD) in subjects without diabetes mellitus (DM). However, their contribution in patients with DM is controve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d5c4c2041744d8019791ff52d07ec0
https://doi.org/10.1016/s0167-5273(00)00304-1
https://doi.org/10.1016/s0167-5273(00)00304-1
Publikováno v:
Thrombosis Research. 94:33-44
The mechanisms for regulating platelet HDL3 binding sites were investigated. HDL3 binding was rapid (T1/2 association=4 minutes) and completely reversible (T1/2 dissociation=14.5 minutes) at 4°C, 22°C, and 37°C, and kinetic analysis yielded forwar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab7c109f9ff51a7a6fff499e3b82332c
https://doi.org/10.1016/s0049-3848(98)00196-0
https://doi.org/10.1016/s0049-3848(98)00196-0
Publikováno v:
Scopus-Elsevier
BACKGROUND It is speculated that, as a result of its tissue selectivity, pravastatin may be a safer drug than the lipophilic 3-hydroxy-3-methylglutaryl Coenzyme A (HMG-CoA) reductase inhibitors in combination therapy involving drugs with potential mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e990069ca035ec5c40ef87ba93fbcbc
https://doi.org/10.1097/00019501-199412000-00003
https://doi.org/10.1097/00019501-199412000-00003
Autor:
C de Castellarnau, Javier Pedreño, Francesc González-Sastre, R Ortín, J L Sánchez, R. Llopart, C Cullaré
Publikováno v:
Arteriosclerosis and Thrombosis: A Journal of Vascular Biology. 14:401-408
We have recently demonstrated that the platelet low-density lipoprotein (LDL) receptor is immunologically different from the "classic" receptor of nucleated cells. We undertook the current studies to investigate the interaction of this receptor with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e158f8ff58867d75e17894a87dd7aa2f
https://doi.org/10.1161/01.atv.14.3.401
https://doi.org/10.1161/01.atv.14.3.401
Autor:
C Cullaré, Javier Pedreño, J L Sánchez, Jordi Ordóñez-Llanos, Juan A Gómez-Gerique, Francesc González-Sastre, C de Castellarnau
Publikováno v:
Scopus-Elsevier
Washed human platelets bound radioiodinated low density lipoprotein (125I-LDL) to a class of saturable binding sites; they numbered 1,348 +/- 126 per platelet, and the dissociation constant (KD) was 50.7 +/- 9 nM. 125I-LDL binding to platelets was re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd376ab0b4c93c16d87614bbda826856
https://doi.org/10.1161/01.atv.12.11.1353
https://doi.org/10.1161/01.atv.12.11.1353