Zobrazeno 1 - 10
of 268
pro vyhledávání: '"Javier Palazon"'
Autor:
Miguel Angel Alcalde, Diego Hidalgo-Martinez, Roque Bru Martínez, Susana Sellés-Marchart, Mercedes Bonfill, Javier Palazon
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
Recent advancements in plant biotechnology have highlighted the potential of hairy roots as a biotechnological platform, primarily due to their rapid growth and ability to produce specialized metabolites. This study aimed to delve deeper into hairy r
Externí odkaz:
https://doaj.org/article/a60e002dae444ab7a25f657396f8be56
Publikováno v:
Plants, Vol 12, Iss 19, p 3363 (2023)
Centella asiatica is a medicinal plant with a rich tradition of use for its therapeutic properties. Among its bioactive compounds are centellosides, a group of triterpenoid secondary metabolites whose potent pharmacological activities have attracted
Externí odkaz:
https://doaj.org/article/a2555d8339f44de1b2a63739713227aa
Autor:
Edgar Perez-Matas, Diego Hidalgo-Martinez, Ainoa Escrich, Miguel Angel Alcalde, Elisabeth Moyano, Mercedes Bonfill, Javier Palazon
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
Paclitaxel (PTX) and its derivatives are diterpene alkaloids widely used as chemotherapeutic agents in the treatment of various types of cancer. Due to the scarcity of PTX in nature, its production in cell cultures and plant organs is a major challen
Externí odkaz:
https://doaj.org/article/17808a83f7f0455089140f2d217ef975
Autor:
Miguel Angel Alcalde, Maren Müller, Sergi Munné-Bosch, Mariana Landín, Pedro Pablo Gallego, Mercedes Bonfill, Javier Palazon, Diego Hidalgo-Martinez
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Hairy roots are made after the integration of a small set of genes from Agrobacterium rhizogenes in the plant genome. Little is known about how this small set is linked to their hormone profile, which determines development, morphology, and levels of
Externí odkaz:
https://doaj.org/article/12095d20aea3424ba2a5671d8c3a9287
Autor:
Edgar Perez-Matas, Pascual Garcia-Perez, Begoña Miras-Moreno, Luigi Lucini, Mercedes Bonfill, Javier Palazon, Diego Hidalgo-Martinez
Publikováno v:
Plants, Vol 12, Iss 14, p 2696 (2023)
Taxus cell cultures are a reliable biotechnological source of the anticancer drug paclitaxel. However, the interplay between taxane production and other metabolic pathways during elicitation remains poorly understood. In this study, we combined untar
Externí odkaz:
https://doaj.org/article/550dc5229b14462b940aca5edc3e7dac
Autor:
Edgar Perez-Matas, Abdulsamie Hanano, Elisabeth Moyano, Mercedes Bonfill, Rosa M. Cusido, Javier Palazon
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
More knowledge is needed about the molecular/cellular control of paclitaxel (PTX) production in Taxus spp. cell cultures. In this study, the yield of this anticancer agent in Taxus baccata cell suspensions was improved 11-fold after elicitation with
Externí odkaz:
https://doaj.org/article/2907f2452635478ab2d2272ed0ec5f15
Autor:
Ainoa Escrich, Rosa M. Cusido, Mercedes Bonfill, Javier Palazon, Raul Sanchez-Muñoz, Elisabeth Moyano
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Environmental conditions are key factors in the modulation of the epigenetic mechanisms regulating gene expression in plants. Specifically, the maintenance of cell cultures in optimal in vitro conditions alters methylation patterns and, consequently,
Externí odkaz:
https://doaj.org/article/a563a004cd504128aa2bb65e86e109ec
Autor:
Edgar Perez-Matas, Pascual Garcia-Perez, Mercedes Bonfill, Luigi Lucini, Diego Hidalgo-Martinez, Javier Palazon
Publikováno v:
Antioxidants, Vol 12, Iss 4, p 887 (2023)
Elicited cell cultures of Taxus spp. are successfully used as sustainable biotechnological production systems of the anticancer drug paclitaxel, but the effect of the induced metabolomic changes on the synthesis of other bioactive compounds by elicit
Externí odkaz:
https://doaj.org/article/f0ac2eb5170a41a19821ae16504179a6
Autor:
Harshita Gaurav, Divyanshu Yadav, Ankita Maurya, Himanshu Yadav, Ramanand Yadav, Amritesh Chandra Shukla, Minaxi Sharma, Vijai Kumar Gupta, Javier Palazon
Publikováno v:
Molecules, Vol 28, Iss 3, p 1208 (2023)
Withania somnifera L. Dunal (Ashwagandha), a key medicinal plant native to India, is used globally to manage various ailments. This review focuses on the traditional uses, botany, phytochemistry, and pharmacological advances of its plant-derived cons
Externí odkaz:
https://doaj.org/article/00cc4d979b06492b98aa79b98cfa4268
Autor:
Miguel Angel Alcalde, Edgar Perez-Matas, Ainoa Escrich, Rosa M. Cusido, Javier Palazon, Mercedes Bonfill
Publikováno v:
Molecules, Vol 27, Iss 16, p 5253 (2022)
One of the aims of plant in vitro culture is to produce secondary plant metabolites using plant cells and organ cultures, such as cell suspensions, adventitious, and hairy roots (among others). In cases where the biosynthesis of a compound in the pla
Externí odkaz:
https://doaj.org/article/6e54744b062c441b961beb64c8094ae7