Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Javier Muñoz-Garcia"'
Autor:
Camille Jubelin, Javier Muñoz-Garcia, Denis Cochonneau, Emilie Ollivier, François Vallette, Marie-Françoise Heymann, Lisa Oliver, Dominique Heymann
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Introduction: The mechanisms involved in cancer initiation, progression, drug resistance, and disease recurrence are traditionally investigated through in vitro adherent monolayer (2D) cell models. However, solid malignant tumor growth is characteriz
Externí odkaz:
https://doaj.org/article/5be8afa603d64990a6df9702d6a2bb23
Autor:
Camille Jubelin, Javier Muñoz-Garcia, Laurent Griscom, Denis Cochonneau, Emilie Ollivier, Marie-Françoise Heymann, François M. Vallette, Lisa Oliver, Dominique Heymann
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-28 (2022)
Abstract Cancer is a multifactorial disease that is responsible for 10 million deaths per year. The intra- and inter-heterogeneity of malignant tumors make it difficult to develop single targeted approaches. Similarly, their diversity requires variou
Externí odkaz:
https://doaj.org/article/84b740defb9b4117a2050fe94319241d
Autor:
Clément J.F. Heymann, Christine Bobin-Dubigeon, Javier Muñoz-Garcia, Denis Cochonneau, Emilie Ollivier, Marie-Françoise Heymann, Dominique Heymann
Publikováno v:
Journal of Bone Oncology, Vol 36, Iss , Pp 100451- (2022)
Osteosarcoma (OS) is a rare malignant primary bone tumours characterized by a high genetic and cell composition heterogeneity. Unfortunately, despite the use of drug combinations and the recent development of immunotherapies, the overall survival has
Externí odkaz:
https://doaj.org/article/fc7bf4d197b84970a04d270624959e68
Autor:
Perrine Jacquot, Javier Muñoz-Garcia, Maurine Fleury, Denis Cochonneau, Rémi Gaussin, Elise Enouf, Caroline Roze, Emilie Ollivier, Mathieu Cinier, Dominique Heymann
Publikováno v:
Biomolecules, Vol 13, Iss 4, p 636 (2023)
Re-education of the tumor microenvironment with immune checkpoint inhibitors (ICI) has provided the most significant advancement in cancer management, with impressive efficacy and durable response reported. However, low response rates and a high freq
Externí odkaz:
https://doaj.org/article/7ae2e14e7a294c4092b3471af5a93db7
Autor:
Javier Muñoz-Garcia, Mattia Mazza, Cyrille Alliot, Corinne Sinquin, Sylvia Colliec-Jouault, Dominique Heymann, Sandrine Huclier-Markai
Publikováno v:
Marine Drugs, Vol 19, Iss 3, p 174 (2021)
Antimetastatic properties on both murine and human osteosarcoma cell lines (POS-1 and KHOS) have been evidenced using exopolysaccharide (EPS) derivatives, produced by Alteromonas infernus bacterium. These derivatives had no significant effect on the
Externí odkaz:
https://doaj.org/article/b6a29497cee2436799cb219529f3a420
Autor:
Marc Fouassier, Javier Muñoz-Garcia, Paul E. Monahan, Marie Cadé, Antoine Babuty, Marie-Françoise Heymann, Dominique Heymann
Publikováno v:
Drug Discovery Today. 27:102-116
Hemophilia A is an X-linked hereditary disorder that results from deficient coagulation factor VIII (FVIII) activity, leading to spontaneous bleeding episodes, particularly in joints and muscles. FVIII deficiency has been associated with altered bone
Autor:
Javier Muñoz-Garcia, Dominique Heymann, Irina Giurgea, Marie Legendre, Serge Amselem, Beatriz Castañeda, Frédéric Lézot, Jorge William Vargas-Franco
Publikováno v:
Biochemical Pharmacology. 213:115584
Autor:
Javier Muñoz-Garcia, Jorge William Vargas-Franco, Bénédicte Brounais-Le Royer, Denis Cochonneau, Jérôme Amiaud, Marie-Françoise Heymann, Dominique Heymann, Frédéric Lézot
Publikováno v:
Cancers; Volume 14; Issue 7; Pages: 1765
Cancers
Cancers, 2022, 14 (7), pp.1765. ⟨10.3390/cancers14071765⟩
Cancers
Cancers, 2022, 14 (7), pp.1765. ⟨10.3390/cancers14071765⟩
International audience; Current treatments for osteosarcoma, combining conventional polychemotherapy and surgery, make it possible to attain a five-year survival rate of 70% in affected individuals. The presence of chemoresistance and metastases sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef068316855c2e6f64abc48284d37ba2
https://eprints.whiterose.ac.uk/185835/1/cancers-14-01765-v2.pdf
https://eprints.whiterose.ac.uk/185835/1/cancers-14-01765-v2.pdf
Autor:
Marie Cadé, Javier Muñoz-Garcia, Antoine Babuty, Louis Paré, Denis Cochonneau, Karim Fekir, Mathias Chatelais, Marie-Françoise Heymann, Anna Lokajczyk, Catherine Boisson-Vidal, Dominique Heymann
Publikováno v:
Cellular and Molecular Life Sciences. 79
Hemophilia A is an inherited X-linked recessive bleeding disorder caused by deficient activity of blood coagulation factor VIII (FVIII). In addition, hemophilia patients show associated diseases including osteopenia, altered inflammation and vascular
Autor:
Camille Jubelin, Javier Muñoz-Garcia, Denis Cochonneau, Emilie Moranton, Marie-Françoise Heymann, Dominique Heymann
Publikováno v:
Cancer Drug Resistance
Cancer Drug Resistance, 2022, 5, ⟨10.20517/cdr.2021.130⟩
Cancer Drug Resistance, 2022, 5, ⟨10.20517/cdr.2021.130⟩
International audience; Sarcomas are a large family of cancers originating in the mesenchyme. Composed of more than 100 histological subtypes, soft tissue and bone sarcomas remain clinically challenging, particularly in children and adolescents in wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1889b255a82b54aa9794afde117993a
https://eprints.whiterose.ac.uk/185843/1/4584.pdf
https://eprints.whiterose.ac.uk/185843/1/4584.pdf