Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Javier Mercapide"'
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e53364 (2012)
A number of studies have shown that tumor cells fuse with other tumor and non-tumor cells. In the present study on tumor cell lines derived from glioblastoma, breast cancer, and melanoma, we estimated the frequency of fusion between tumor cells by es
Externí odkaz:
https://doaj.org/article/d148d550714e4eccb400bfba3d1ad292
Autor:
Andres J. Klein-Szanto, Javier S. Castresana, Daniel E. Bassi, Gary Thomas, Ricardo Lopez de Cicco, Javier Mercapide
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 25(8)
Purpose: Astrocytoma arises in the central nervous system as a tumorof great lethality, in part because of the invasive potential of the neoplastic cells that are able to release extracellular matrix-degrading enzymes. Furin convertase activates seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31f2d738b542f49691027bd040baedee
https://pubmed.ncbi.nlm.nih.gov/12060611
https://pubmed.ncbi.nlm.nih.gov/12060611
Autor:
Aurelio Lorico, Javier Mercapide
Publikováno v:
International Journal of Molecular Medicine. 34:1365-1371
An increase in ploidy (polyploidization) causes genomic instability in cancer. However, the determinants for the increased DNA content of cancer cells have not yet been fully elucidated. In the present study, we investigated whether adhesion induces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e57099d999b61aa781aaad8447fbaf4e
https://doi.org/10.3892/ijmm.2014.1913
https://doi.org/10.3892/ijmm.2014.1913
Autor:
Lina Prasmickaite, Øystein Fodstad, Jingfang Ju, Fabio Anzanello, Aurelio Lorico, Javier Mercapide, Yaguang Xi, Germana Rappa
Publikováno v:
Experimental Cell Research. 314:2110-2122
Malignant tumors comprise a small proportion of cancer-initiating cells (CIC), capable of sustaining tumor formation and growth. CIC are the main potential target for anticancer therapy. However, the identification of molecular therapeutic targets in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::992e73bf18e4de11cb4a798dab27e2f1
https://doi.org/10.1016/j.yexcr.2008.03.008
https://doi.org/10.1016/j.yexcr.2008.03.008
Autor:
Arthur S. Patchefsky, Íñigo López de la Osa, Shi Yu Zhang, Andres J. Klein-Szanto, Javier Mercapide, José Schneider, Javier S. Castresana, Vicente Furio-bacete, Xing Fan
Publikováno v:
Molecular Carcinogenesis. 35:6-12
Because of the relatively low incidence of lobular breast carcinoma, there are very few studies on the molecular characteristics of this breast cancer. In an attempt to improve its characterization, we investigated in a large collection of invasive l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::579c460a5cafba086e8a7fb0cbcfe214
https://doi.org/10.1002/mc.10069
https://doi.org/10.1002/mc.10069
Publikováno v:
Advances in experimental medicine and biology. 777
Innovative approaches to specifically target the melanoma subpopulation responsible for local invasion and metastatic dissemination are needed. Prominin-1 (CD133) expression has been observed in many melanoma cell lines, as well as in primary and met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2698cf184b191d967210d73e901186f7
https://pubmed.ncbi.nlm.nih.gov/23161084
https://pubmed.ncbi.nlm.nih.gov/23161084
Publikováno v:
Prominin-1 (CD133): New Insights on Stem & Cancer Stem Cell Biology ISBN: 9781461458937
Innovative approaches to specifically target the melanoma subpopulation responsible for local invasion and metastatic dissemination are needed. Prominin-1 (CD133) expression has been observed in many melanoma cell lines, as well as in primary and met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7841ce26371e32e207e85512a86a2d54
https://doi.org/10.1007/978-1-4614-5894-4_13
https://doi.org/10.1007/978-1-4614-5894-4_13
Autor:
Mary G. Johlfs, Denis Corbeil, Aurelio Lorico, Javier Mercapide, Fabio Anzanello, Michaela Wilsch-Bräuninger, Ronald R. Fiscus, Germana Rappa, Thuc T. Le
Publikováno v:
Experimental cell research. 319(6)
Prominin-1 (CD133) is the first identified gene of a novel class of pentaspan membrane glycoproteins. It is expressed by various epithelial and non-epithelial cells, and notably by stem and cancer stem cells. In non-cancerous cells such as neuro-epit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265b40d5364a0facd312d88d32ef7be3
https://pubmed.ncbi.nlm.nih.gov/23318676
https://pubmed.ncbi.nlm.nih.gov/23318676
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 12, p e53364 (2012)
PLoS ONE, Vol 7, Iss 12, p e53364 (2012)
A number of studies have shown that tumor cells fuse with other tumor and non-tumor cells. In the present study on tumor cell lines derived from glioblastoma, breast cancer, and melanoma, we estimated the frequency of fusion between tumor cells by es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac8ba414d36241ae4c57dcf853c8a11
https://pubmed.ncbi.nlm.nih.gov/23300919
https://pubmed.ncbi.nlm.nih.gov/23300919
Publikováno v:
International journal of cancer. 131(2)
We have previously reported in vitro heterotypic fusion of glioma cells with neural progenitor cells, producing tetraploid cells expressing genetic complements of each partner. Herein, we investigated the fusogenicity of glioma cells. In 1:1 cocultur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6985181c367c73077fee775c45fb8d16
https://pubmed.ncbi.nlm.nih.gov/21858806
https://pubmed.ncbi.nlm.nih.gov/21858806