Zobrazeno 1 - 10
of 313
pro vyhledávání: '"Javier Martinez Picado"'
Publikováno v:
Pathogens and Immunity, Vol 8, Iss 1 (2023)
The inaugural FASEB HIV Reservoirs and Immune Control Conference brought researchers together from across the globe to discuss reservoir dynamics in clinical cohorts. It extended over 4 days in the seaside town of Malahide, Ireland. The scientific se
Externí odkaz:
https://doaj.org/article/d0eb302487b14973a85a09382e436e05
Autor:
Alessandra Borgognone, Marc Noguera-Julian, Bruna Oriol, Laura Noël-Romas, Marta Ruiz-Riol, Yolanda Guillén, Mariona Parera, Maria Casadellà, Clara Duran, Maria C. Puertas, Francesc Català-Moll, Marlon De Leon, Samantha Knodel, Kenzie Birse, Christian Manzardo, José M. Miró, Bonaventura Clotet, Javier Martinez-Picado, José Moltó, Beatriz Mothe, Adam Burgener, Christian Brander, Roger Paredes, the BCN02 Study Group
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract Background The potential role of the gut microbiome as a predictor of immune-mediated HIV-1 control in the absence of antiretroviral therapy (ART) is still unknown. In the BCN02 clinical trial, which combined the MVA.HIVconsv immunogen with
Externí odkaz:
https://doaj.org/article/f4eb4630f5eb4505a01baefcff14f0eb
Autor:
Ifeanyi Jude Ezeonwumelu, Edurne García-Vidal, Eudald Felip, Maria C. Puertas, Bruna Oriol-Tordera, Lucía Gutiérrez-Chamorro, André Gohr, Marta Ruiz-Riol, Marta Massanella, Bonaventura Clotet, Javier Martinez-Picado, Roger Badia, Eva Riveira-Muñoz, Ester Ballana
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The persistence of latent HIV reservoirs allows for viral rebound upon antiretroviral therapy interruption, hindering effective HIV-1 cure. Emerging evidence suggests that modulation of innate immune stimulation could impact viral latency and contrib
Externí odkaz:
https://doaj.org/article/0c134c9371f546d1bf28e34f8645f39a
Autor:
James L Gulley, Elad Sharon, Julius Strauss, Steven P Fling, Anna Wright, Teresa Moran, Kathryn Lurain, Ramya Ramaswami, Thomas S Uldrick, Robert Yarchoan, Maria Gonzalez-Cao, Javier Martinez-Picado, Thomas A Odeny
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Background The Food and Drug Administration recommends that people living with HIV (PWH) with a CD4+ T cell count (CD4) ≥350 cells/µL may be eligible for any cancer clinical trial, but there is reluctance to enter patients with lower CD4 counts in
Externí odkaz:
https://doaj.org/article/040ee9ed4fc648b5b5356b0d33884972
Autor:
Jon Izquierdo-Pujol, Sara Moron-Lopez, Judith Dalmau, Alba Gonzalez-Aumatell, Clara Carreras-Abad, Maria Mendez, Carlos Rodrigo, Javier Martinez-Picado
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection became a pandemic in 2020 and by March 2022 had caused more than 479 million infections and 6 million deaths worldwide. Several acute and long-term symptoms have been reported
Externí odkaz:
https://doaj.org/article/8608b7172a7140aaa764ccbe44092eb3
Autor:
Haruka Toda, Miriam Diaz-Varela, Joan Segui-Barber, Wanlapa Roobsoong, Barbara Baro, Susana Garcia-Silva, Alicia Galiano, Melisa Gualdrón-López, Anne C. G. Almeida, Marcelo A. M. Brito, Gisely Cardoso de Melo, Iris Aparici-Herraiz, Carlos Castro-Cavadía, Wuelton Marcelo Monteiro, Eva Borràs, Eduard Sabidó, Igor C. Almeida, Jakub Chojnacki, Javier Martinez-Picado, Maria Calvo, Pilar Armengol, Jaime Carmona-Fonseca, Maria Fernanda Yasnot, Ricardo Lauzurica, Antonio Marcilla, Hector Peinado, Mary R. Galinski, Marcus V. G. Lacerda, Jetsumon Sattabongkot, Carmen Fernandez-Becerra, Hernando A. del Portillo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Extracellular vesicles (EVs) in plasma can affect pathogenesis of parasites, but details remain unclear. Here, Toda et al. characterize plasma-derived EVs from Plasmodium vivax patients and show that PvEVs are preferentially taken up by human spleen
Externí odkaz:
https://doaj.org/article/ed64effa50a745ce91636d1f3b6a2c54
Autor:
Emily Adland, Jane Millar, Nomonde Bengu, Maximilian Muenchhoff, Rowena Fillis, Kenneth Sprenger, Vuyokasi Ntlantsana, Julia Roider, Vinicius Vieira, Katya Govender, John Adamson, Nelisiwe Nxele, Christina Ochsenbauer, John Kappes, Luisa Mori, Jeroen van Lobenstein, Yeney Graza, Kogielambal Chinniah, Constant Kapongo, Roopesh Bhoola, Malini Krishna, Philippa C. Matthews, Ruth Penya Poderos, Marta Colomer Lluch, Maria C. Puertas, Julia G. Prado, Neil McKerrow, Moherndran Archary, Thumbi Ndung’u, Andreas Groll, Pieter Jooste, Javier Martinez-Picado, Marcus Altfeld, Philip Goulder
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Sex differences in the immune response to vaccines and infections have been well described in children and adults. Here the authors describe, in a cohort of 177 HIV-infected infants, innate immune sex differences in fetal life that increase female su
Externí odkaz:
https://doaj.org/article/b55696a6d6ee44ba9f20d18889681d90
Autor:
Concepcion Casado, Cristina Galvez, Maria Pernas, Laura Tarancon-Diez, Carmen Rodriguez, Víctor Sanchez-Merino, Mar Vera, Isabel Olivares, Rebeca De Pablo-Bernal, Alberto Merino-Mansilla, Jorge Del Romero, Ramon Lorenzo-Redondo, Ezequiel Ruiz-Mateos, María Salgado, Javier Martinez-Picado, Cecilio Lopez-Galindez
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract Elite controllers (EC) represent a small subset of HIV-1-infected people that spontaneously control viral replication. However, natural virological suppression and absence of immune dysfunction are not always long-term sustained. We define e
Externí odkaz:
https://doaj.org/article/9afa80bdaabf490c8c3d29884df46882
Autor:
Cristina Gálvez, Judith Grau-Expósito, Victor Urrea, Bonaventura Clotet, Vicenç Falcó, Maria José Buzón, Javier Martinez-Picado
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT Knowing the mechanisms that govern the persistence of infected CD4+ subpopulations could help us to design new therapies to cure HIV-1 infection. We evaluated the simultaneous distribution of the HIV-1 reservoir in 13 CD4+ subpopulations fro
Externí odkaz:
https://doaj.org/article/43b6569eee9c4bb6b0fdd961df30d841
Autor:
Vinicius A Vieira, Emily Adland, David F G Malone, Maureen P Martin, Andreas Groll, M Azim Ansari, Maria C Garcia-Guerrero, Mari C Puertas, Maximilian Muenchhoff, Claudia Fortuny Guash, Christian Brander, Javier Martinez-Picado, Alasdair Bamford, Gareth Tudor-Williams, Thumbi Ndung'u, Bruce D Walker, Veron Ramsuran, John Frater, Pieter Jooste, Dimitra Peppa, Mary Carrington, Philip J R Goulder
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1010090 (2021)
Natural Killer (NK) cells contribute to HIV control in adults, but HLA-B-mediated T-cell activity has a more substantial impact on disease outcome. However, the HLA-B molecules influencing immune control in adults have less impact on paediatric infec
Externí odkaz:
https://doaj.org/article/2772898860cf475e98f5416e7e2940e4