Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Javier Lepe"'
Autor:
Chris Douglas, Naomi Lomeli, Javier Lepe, Kaijun Di, Nitesh Kumar Nandwana, Thao Vu, James Pham, Maria Cristina Kenney, Bhaskar Das, Daniela A. Bota
Publikováno v:
bioRxiv
Malignant astrocytomas are aggressive glioma tumors that have poor prognosis and limited treatments available following recurrence. These tumors are characterized by extensive hypoxia-induced, mitochondria-dependent changes such as glycolytic respira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc30851249d5782bac0bbc4872d1c46
https://europepmc.org/articles/PMC10153114/
https://europepmc.org/articles/PMC10153114/
Autor:
Javier Lepe, Clay Hoerig, Naomi Lomeli, Ashley Plant-Fox, Christopher J. Douglas, Bhaskar Das, Kaijun Di, Daniela A. Bota
Publikováno v:
Neuro-Oncology, vol 23, iss Supplement_6
Neuro-oncology, vol 23, iss Suppl 6
Neuro Oncol
Neuro-oncology, vol 23, iss Suppl 6
Neuro Oncol
BACKGROUND Brain tumors are the second most common type of pediatric cancer and are the leading cause of all cancer-related deaths in children. Medulloblastoma (MB) is the most common type of malignant pediatric brain tumor and has a five-year overal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::678bd814b77211cded51e54525e96c81
https://escholarship.org/uc/item/699783dr
https://escholarship.org/uc/item/699783dr
Publikováno v:
Neuro-Oncology, vol 23, iss Supplement_6
Neuro Oncol
Neuro Oncol
Glioblastoma (GBM), a WHO grade IV brain cancer, exhibits strong treatment resistance and a high rate of reoccurrence, which gives it a dismal prognosis, a 5% survival rate in the first 5 years. LonP1, a mitochondrial master regulator, can drive meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071f053b5f31147cd95e1ed800543016
https://escholarship.org/uc/item/7vf4s9p3
https://escholarship.org/uc/item/7vf4s9p3
Publikováno v:
Neuro-Oncology. 24:vii262-vii262
The dynamic nature of tumor microenvironments contributes to tumor heterogeneity generating subpopulations of cells that are resistant to treatment in glioblastoma (GBM). The high recurrent rate of GBM tumors in patients can partially be explained by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40d0de2d2fce55f058a10f74ce4f5be8
https://doi.org/10.1093/neuonc/noac209.1010
https://doi.org/10.1093/neuonc/noac209.1010
Publikováno v:
Neuro-Oncology. 24:vii37-vii37
Glioblastoma (GBM), a high grade brain tumor, possesses poor overall survival with less than 5% surviving past five years. Previously, the TCGA classifications for GBM have included the mesenchymal, proneural, classical and neural subtypes with their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e32a51e7cdff823eb3b5c33012ffd5cb
https://doi.org/10.1093/neuonc/noac209.145
https://doi.org/10.1093/neuonc/noac209.145
Autor:
Emily K. Reinhardt, Theodore V. Nguyen, Andrew T Marshall, Vincent Torrecampo, Javier Lepe, Karla Echeverria, Nicole Midani, Sara H. Bertan, Serinee H. Tran, Cherie A Lepe, Brian J. Cummings, Anna Badner, Aileen J. Anderson
Publikováno v:
Journal of neurotrauma. 38(19)
Human neural stem cells (hNSCs) have potential as a cell therapy after traumatic brain injury (TBI). While various studies have demonstrated the efficacy of NSCs from ongoing culture, there is a significant gap in our understanding of freshly thawed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f37935d706883784bcb83789e837ed3
https://pubmed.ncbi.nlm.nih.gov/34130484
https://pubmed.ncbi.nlm.nih.gov/34130484
Publikováno v:
FASEB BioAdvances
FASEB BioAdvances, Vol 3, Iss 3, Pp 136-142 (2021)
FASEB BioAdvances, Vol 3, Iss 3, Pp 136-142 (2021)
At the University of California, Irvine, School of Medicine (UCISOM), the COVID‐19 pandemic is accelerating the transition of face‐to‐face didactic lectures to online platforms. Institutions nationwide have opted to transition their lectures in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97824ed7b9ed89944c77e69e6a240f1c
https://pubmed.ncbi.nlm.nih.gov/33733055
https://pubmed.ncbi.nlm.nih.gov/33733055
Autor:
Serinee H. Tran, Vincent Torrecampo, Andrew T Marshall, Emily K. Reinhardt, Javier Lepe, Theodore V. Nguyen, Anna Badner, Nicole Midani, Karla Echeverria, Brian J. Cummings, Aileen J. Anderson, Sara H. Bertan, Cherie A Lepe
Human neural stem cells (hNSCs) have potential as a cell therapy following traumatic brain injury (TBI). While various studies have demonstrated the efficacy of NSCs from on-going culture, there is a significant gap in our understanding of freshly th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c6ffad039a0a544b907f27b0df52f84
https://doi.org/10.1101/2020.07.23.212423
https://doi.org/10.1101/2020.07.23.212423
Publikováno v:
Neuro-Oncology, vol 23, iss Supplement_6
Glioblastoma (WHO Grade IV glioma) is the most aggressive brain cancer. The current standard of care treatment includes surgery, radiation, and chemotherapy. Tumor recurrence is almost inevitable as less than 50% of patients survive more than two yea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dbd97b8d0c16ae70558a968f64c45cb
https://doi.org/10.1093/neuonc/noab196.315
https://doi.org/10.1093/neuonc/noab196.315
Publikováno v:
Neuro Oncol
Neuro-oncology, vol 22, iss Suppl 2
Neuro-Oncology, vol 22, iss Supplement_2
Neuro-oncology, vol 22, iss Suppl 2
Neuro-Oncology, vol 22, iss Supplement_2
BACKGROUNDS Glioblastoma (GBM) is an aggressive infiltrative brain tumor, and has an extremely poor prognosis despite the use of multiple treatment modalities, including surgery, radiation, and chemotherapy. Meanwhile, mitochondrial changes represent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798af6470d14a8c43485da37b1a8568c
https://doi.org/10.1093/neuonc/noaa215.373
https://doi.org/10.1093/neuonc/noaa215.373