Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Javier López‐Andarias"'
Autor:
Quentin Laurent, Rémi Martinent, Bumhee Lim, Anh-Tuan Pham, Takehiro Kato, Javier López-Andarias, Naomi Sakai, Stefan Matile
Publikováno v:
JACS Au, Vol 1, Iss 6, Pp 710-728 (2021)
Externí odkaz:
https://doaj.org/article/934547d5f5734de5886a3df89bb6561a
Autor:
Javier López-Andarias, Karolína Straková, Rémi Martinent, Noemi Jiménez-Rojo, Howard Riezman, Naomi Sakai, Stefan Matile
Publikováno v:
JACS Au, Vol 1, Iss 2, Pp 221-232 (2021)
Externí odkaz:
https://doaj.org/article/62ae4df08800439981b7c4f4b20cdf7d
Autor:
Rémi Martinent, Javier López-Andarias, Dimitri Moreau, Yangyang Cheng, Naomi Sakai, Stefan Matile
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 2007-2016 (2020)
Recent progress with chemistry tools to deliver into living cells has seen a shift of attention from counterion-mediated uptake of cell-penetrating peptides (CPPs) and their mimics, particularly the Schmuck cation, toward thiol-mediated uptake with c
Externí odkaz:
https://doaj.org/article/420fd0a7a26a478a9a37a97d63e7bff9
Autor:
Karolína Straková, Javier López-Andarias, Noemi Jiménez-Rojo, Joseph E. Chambers, Stefan J. Marciniak, Howard Riezman, Naomi Sakai, Stefan Matile
Publikováno v:
ACS Central Science, Vol 6, Iss 8, Pp 1376-1385 (2020)
Externí odkaz:
https://doaj.org/article/2cbf73242a1f433bb8c220a3ef07b9c5
Autor:
Lea Assies, José García-Calvo, Francesca Piazzolla, Samantha Sanchez, Takehiro Kato, Luc Reymond, Antoine Goujon, Adai Colom, Javier López-Andarias, Karolína Straková, Dora Mahecic, Vincent Mercier, Margot Riggi, Noemi Jiménez-Rojo, Chloé Roffay, Giuseppe Licari, Maria Tsemperouli, Frederik Neuhaus, Alexandre Fürstenberg, Eric Vauthey, Sascha Hoogendoorn, Marcos Gonzalez-Gaitan, Andreas Zumbuehl, Kaori Sugihara, Jean Gruenberg, Howard Riezman, Robbie Loewith, Suliana Manley, Aurelien Roux, Nicolas Winssinger, Naomi Sakai, Stefan Pitsch, Stefan Matile
Publikováno v:
CHIMIA, Vol 75, Iss 12 (2021)
This article describes four fluorescent membrane tension probes that have been designed, synthesized, evaluated, commercialized and applied to current biology challenges in the context of the NCCR Chemical Biology. Their names are Flipper-TR©, ER Fl
Externí odkaz:
https://doaj.org/article/bc42a5ddeb734d338971c739fd7fea45
Autor:
José García-Calvo, Javier López-Andarias, Jimmy Maillard, Vincent Mercier, Chloé Roffay, Aurélien Roux, Alexandre Fürstenberg, Naomi Sakai, Stefan Matile
Publikováno v:
Chemical science, Vol. 13, No 7 (2022) pp. 2086-2093
HydroFlippers are introduced as the first fluorescent membrane tension probes that report simultaneously on membrane compression and hydration. The probe design is centered around a sensing cycle that couples the mechanical planarization of twisted p
Autor:
Chloé Roffay, Juan Manuel García-Arcos, Pierrik Chapuis, Javier López-Andarias, Falk Schneider, Adai Colom, Caterina Tomba, Ilaria Di Meglio, Valentin Dunsig, Stefan Matile, Aurélien Roux, Vincent Mercier
Measuring forces within living cells remains a technical challenge. We developed hydrophobic mechanosensing fluorescent probes called Flippers, whose fluorescence lifetime depends on lipid packing and can report on membrane tension. Here, we describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5955a207fb895f20afe5456742d01935
https://doi.org/10.1101/2022.09.28.509885
https://doi.org/10.1101/2022.09.28.509885
Autor:
Lea Assies, Vincent Mercier, Javier López‐Andarias, Aurelien Roux, Naomi Sakai, Stefan Matile
Publikováno v:
ChemBioChem. 23
Autor:
Lea Assies, Vincent Mercier, Javier López‐Andarias, Aurelien Roux, Naomi Sakai, Stefan Matile
Publikováno v:
Chembiochem : a European journal of chemical biology. 23(15)
Labeled ammonium cations with pK
Publikováno v:
Chemical Communications, Vol. 57, No 32 (2021) pp. 3913-3916
Despite their growing popularity in biology to image membrane tension, central design principles of flipper probes have never been validated. Here we report that upon deletion of their primary dipole, from electron-poor and electron-rich dithienothio