Nano-Formulation Endows Quorum Quenching Enzyme-Antibiotic Hybrids with Improved Antibacterial and Antibiofilm Activities against Pseudomonas aeruginosa

Autor: Kristina Ivanova, Aleksandra Ivanova, Javier Hoyo, Silvia Pérez-Rafael, Tzanko Tzanov

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 14, p 7632 (2022)

The emergence of antibiotic resistant bacteria coupled with the shortage of efficient antibacterials is one of the most serious unresolved problems for modern medicine. In this study, the nano-hybridization of the clinically relevant antibiotic, gent

Externí odkaz: https://doaj.org/article/6ee9fc90b0554f95b51584e4e3de2b61

A Fungal Ascorbate Oxidase with Unexpected Laccase Activity

Autor: Verena Braunschmid, Sarah Fuerst, Veronika Perz, Sabine Zitzenbacher, Javier Hoyo, Cesar Fernandez-Sanchez, Tzanko Tzanov, Georg Steinkellner, Karl Gruber, Gibson S. Nyanhongo, Doris Ribitsch, Georg M. Guebitz

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 16, p 5754 (2020)

Ascorbate oxidases are an enzyme group that has not been explored to a large extent. So far, mainly ascorbate oxidases from plants and only a few from fungi have been described. Although ascorbate oxidases belong to the well-studied enzyme family of

Externí odkaz: https://doaj.org/article/f3cc810b70614b4eabce8b6d9225cbd6

Novel Lignin-Capped Silver Nanoparticles against Multidrug-Resistant Bacteria

Autor: Urs O. Häfeli, Javier Hoyo, Tzanko Tzanov, Anne Haegert, Kristina Ivanova, Horacio Bach, Yen-Yi Lin, Aharon Gedanken, Gethin Owen, Stephane LeBihan, Yael N. Slavin, Ilana Perelshtein

Publikováno v: UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)

The emergence of bacteria resistant to antibiotics and the resulting infections are increasingly becoming a public health issue. Multidrug-resistant (MDR) bacteria are responsible for infections leading to increased morbidity and mortality in hospita

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272860630169824d4ca84547f9e332b5
https://doi.org/10.1021/acsami.0c16921

Physical states and thermodynamic properties of model gram-negative bacterial inner membranes

Autor: Javier Hoyo, Juan Torrent-Burgués, Tzanko Tzanov

Publikováno v: UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Recercat. Dipósit de la Recerca de Catalunya
instname

Novel antimicrobial agents are focused to interact with the bacterial membrane whose lipid composition (number and position of unsaturations and lipid headgroup) is adapted according to environmental signals. The anticipation of the adapted membrane

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6665ef1ec6daac7df4328cdf5afa1488
https://doi.org/10.1016/j.chemphyslip.2018.12.003

Lipid-lipid interactions of Escherichia coli mimetic inner membrane at human physiological temperature

Autor: Javier Hoyo, Tzanko Tzanov, Juan Torrent-Burgués

Publikováno v: UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
General physiology and biophysics

The current strategies to eradicate bacteria require that the antimicrobial agent either penetrate or disrupt the bacterial membrane. In Escherichia coli (E.coli) as a model of Gram-negative strains, the antimicrobials have to cross two barriers –

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad9ccc993f8d3b6310ebcee1e622edd
https://hdl.handle.net/2117/183514