Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Javier Hernández-Losa"'
Autor:
Makchit Galadima, Mariana Teles, Josep Pastor, Javier Hernández-Losa, Joan Enric Rodríguez-Gil, Maria Montserrat Rivera del Alamo
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1170 (2024)
Gene expression has been suggested as a putative tool for prognosis and diagnosis in canine mammary neoplasia (CMNs). In the present study, 58 formalin-fixed paraffin-embedded (FFPE) paraffined canine mammary neoplasias from 27 different bitches were
Externí odkaz:
https://doaj.org/article/0d0d2ef8981340e4b33e1096e47fc407
Gene expression profiles of beta-adrenergic receptors in canine vascular tumors: a preliminary study
Autor:
Jordi Clanxet, Mariana Teles, Javier Hernández-Losa, Manuel Ruiz-Echarri Rueda, Luis Benitez-Fusté, Josep Pastor
Publikováno v:
BMC Veterinary Research, Vol 18, Iss 1, Pp 1-7 (2022)
Abstract Beta adrenergic receptors (β-AR) play a key role in regulating several hallmark pathways of both benign and malignant human and canine tumors. There is scarce information on the expression of β-AR in canine vascular tumors. Therefore, the
Externí odkaz:
https://doaj.org/article/5e79eac1d84c4122b0c4a2c593bcc6ab
Autor:
Elena Élez, Núria Mulet-Margalef, Miriam Sanso, Fiorella Ruiz-Pace, Francesco M. Mancuso, Raquel Comas, Javier Ros, Guillem Argilés, Giulia Martini, Enrique Sanz-Garcia, Iosune Baraibar, Francesc Salvà, Alba Noguerido, Jose Luis Cuadra-Urteaga, Roberta Fasani, Ariadna Garcia, Jose Jimenez, Susana Aguilar, Stefania Landolfi, Javier Hernández-Losa, Irene Braña, Paolo Nuciforo, Rodrigo Dienstmann, Josep Tabernero, Ramon Salazar, Ana Vivancos
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 118 (2022)
The search for immunotherapy biomarkers in Microsatellite Instability High/Deficient Mismatch Repair system (MSI-H/dMMR) metastatic colorectal cancer (mCRC) is an unmet need. Sixteen patients with mCRC and MSI-H/dMMR (determined by either immunohisto
Externí odkaz:
https://doaj.org/article/f77ab85a817d47428099bae4d6a1c90a
Autor:
Marta Sesé, Rosa Somoza, Inmaculada Maestu, Maria Martín Ureste, Alfredo Sanchez, Juan Felipe Cordoba, Irene Sansano, Griselda Venturas, Santiago Ramón y Cajal, Javier Hernández-Losa
Publikováno v:
Oncology and Therapy, Vol 7, Iss 2, Pp 131-139 (2019)
Abstract Introduction Precision medicine has revolutionized the understanding and treatment of cancer by identifying subsets of patients who are amenable to specific treatments according to their molecular characteristics, as exemplified by epidermal
Externí odkaz:
https://doaj.org/article/c772a29e300a49fca60185f306821587
Autor:
Iván Prieto-Potin, Nerea Carvajal, Jenifer Plaza-Sánchez, Rebeca Manso, Carmen Laura Aúz-Alexandre, Cristina Chamizo, Sandra Zazo, Almudena López-Sánchez, Socorro María Rodríguez-Pinilla, Laura Camacho, Raquel Longarón, Beatriz Bellosillo, Rosa Somoza, Javier Hernández-Losa, Víctor Manuel Fernández-Soria, Ricardo Ramos-Ruiz, Ion Cristóbal, Jesús García-Foncillas, Federico Rojo
Publikováno v:
PeerJ, Vol 8, p e10069 (2020)
Background Next-generation sequencing (NGS) is a high-throughput technology that has become widely integrated in molecular diagnostics laboratories. Among the large diversity of NGS-based panels, the Trusight Tumor 26 (TsT26) enables the detection of
Externí odkaz:
https://doaj.org/article/6a82bc40e8c845f88d8f03973d27e115
Autor:
Jose A. Lopez-Martin, Ana Arance Fernández, Juan José Ríos-Martín, Javier Hernández-Losa, Lucía Alós Hernández, Pablo Cerezuela Fuentes, Sebastián Ortiz Reina, Eugenia Ortega Izquierdo, Rosa M Martí, Jesús Soberino García, Berta Ferrer Fábrega, José Luis Rodríguez Peralto
Publikováno v:
Translational Oncology, Vol 13, Iss 6, Pp - (2020)
Real-world data on BRAF mutation frequency in advanced melanoma are lacking in Spain. Moreover, data available on clinicopathological profile of patients with advanced BRAF-mutant melanoma are currently limited. This study aimed to assess the frequen
Externí odkaz:
https://doaj.org/article/3bbb0562665e42b2b68b69248b9620e6
Autor:
Inés Martínez-Pena, Pablo Hurtado, Nuria Carmona-Ule, Carmen Abuín, Ana Belén Dávila-Ibáñez, Laura Sánchez, Miguel Abal, Anas Chaachou, Javier Hernández-Losa, Santiago Ramón y Cajal, Rafael López-López, Roberto Piñeiro
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9279 (2021)
Background: Cancer metastasis is a deathly process, and a better understanding of the different steps is needed. The shedding of circulating tumor cells (CTCs) and CTC-cluster from the primary tumor, its survival in circulation, and homing are key ev
Externí odkaz:
https://doaj.org/article/7e40a9b518ce4936846329f1276c83d8
Autor:
Gorka Ruiz de Garibay, Carmen Herranz, Alicia Llorente, Jacopo Boni, Jordi Serra-Musach, Francesca Mateo, Helena Aguilar, Laia Gómez-Baldó, Anna Petit, August Vidal, Fina Climent, Javier Hernández-Losa, Álex Cordero, Eva González-Suárez, José Vicente Sánchez-Mut, Manel Esteller, Roger Llatjós, Mar Varela, José Ignacio López, Nadia García, Ana I Extremera, Anna Gumà, Raúl Ortega, María Jesús Plà, Adela Fernández, Sònia Pernas, Catalina Falo, Idoia Morilla, Miriam Campos, Miguel Gil, Antonio Román, María Molina-Molina, Piedad Ussetti, Rosalía Laporta, Claudia Valenzuela, Julio Ancochea, Antoni Xaubet, Álvaro Casanova, Miguel Angel Pujana
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207586 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0132546.].
Externí odkaz:
https://doaj.org/article/dc0dbc0392fc45b2a2f5604af88deb2e
Autor:
Gorka Ruiz de Garibay, Carmen Herranz, Alicia Llorente, Jacopo Boni, Jordi Serra-Musach, Francesca Mateo, Helena Aguilar, Laia Gómez-Baldó, Anna Petit, August Vidal, Fina Climent, Javier Hernández-Losa, Álex Cordero, Eva González-Suárez, José Vicente Sánchez-Mut, Manel Esteller, Roger Llatjós, Mar Varela, José Ignacio López, Nadia García, Ana I Extremera, Anna Gumà, Raúl Ortega, María Jesús Plà, Adela Fernández, Sònia Pernas, Catalina Falo, Idoia Morilla, Miriam Campos, Miguel Gil, Antonio Román, María Molina-Molina, Piedad Ussetti, Rosalía Laporta, Claudia Valenzuela, Julio Ancochea, Antoni Xaubet, Álvaro Casanova, Miguel Angel Pujana
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132546 (2015)
Lymphangioleiomyomatosis (LAM) is a rare lung-metastasizing neoplasm caused by the proliferation of smooth muscle-like cells that commonly carry loss-of-function mutations in either the tuberous sclerosis complex 1 or 2 (TSC1 or TSC2) genes. While al
Externí odkaz:
https://doaj.org/article/b96bd48beb8a4064a7f089bf1ac9af08
Autor:
Rosaura Esteve-Puig, Rosa Gil, Elena González-Sánchez, Joan Josep Bech-Serra, Judit Grueso, Javier Hernández-Losa, Teresa Moliné, Francesc Canals, Berta Ferrer, Javier Cortés, Boris Bastian, Santiago Ramón Y Cajal, Juan Martín-Caballero, Juana Maria Flores, Ana Vivancos, Vicenç García-Patos, Juan Ángel Recio
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004721 (2014)
Exposure to ultraviolet (UV) radiation from sunlight accounts for 90% of the symptoms of premature skin aging and skin cancer. The tumor suppressor serine-threonine kinase LKB1 is mutated in Peutz-Jeghers syndrome and in a spectrum of epithelial canc
Externí odkaz:
https://doaj.org/article/c3b7bb4d05f143a69b77de7cec7fd350