Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Javier Gutierrez Achury"'
Autor:
Ana Márquez, Martin Kerick, Alexandra Zhernakova, Javier Gutierrez-Achury, Wei-Min Chen, Suna Onengut-Gumuscu, Isidoro González-Álvaro, Luis Rodriguez-Rodriguez, Raquel Rios-Fernández, Miguel A. González-Gay, Coeliac Disease Immunochip Consortium, Rheumatoid Arthritis Consortium International for Immunochip (RACI), International Scleroderma Group, Type 1 Diabetes Genetics Consortium, Maureen D. Mayes, Soumya Raychaudhuri, Stephen S. Rich, Cisca Wijmenga, Javier Martín
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-13 (2018)
Abstract Background In recent years, research has consistently proven the occurrence of genetic overlap across autoimmune diseases, which supports the existence of common pathogenic mechanisms in autoimmunity. The objective of this study was to furth
Externí odkaz:
https://doaj.org/article/b8085b83cdd54702a56f9016218dc0a0
Autor:
Federico Perdomo-Celis, Miguel A. Torres, Henry Ostos, Javier Gutierrez-Achury, Víctor Molano, Luis F. Durán, Guillermo González, Carlos F. Narváez
Publikováno v:
Biomarker Insights, Vol 2015, Iss 10, Pp 125-131 (2015)
Externí odkaz:
https://doaj.org/article/c8a3445e4e9845c5ac995a6e88e27f2a
Autor:
Vinod Kumar, Edgardo Smecuol, Alexander Kurilshikov, Mathieu Platteel, Patrick Deelen, Jingyuan Fu, Oscar Daffra, Serena Sanna, Adriaan van der Graaf, Ana F. Costa, Gosia Trynka, Isis Ricaño-Ponce, Julio C. Bai, Javier Gutierrez-Achury, Sonia I. Niveloni, Cisca Wijmenga, Alexandra Zhernakova, Maria M. Zorro
Publikováno v:
European Journal of Human Genetics, 28, 3, pp. 313-323
Eur J Hum Genet
EJHG, 28(3), 313-323. Nature Publishing Group
European Journal of Human Genetics, 28, 313-323
Eur J Hum Genet
EJHG, 28(3), 313-323. Nature Publishing Group
European Journal of Human Genetics, 28, 313-323
Celiac disease (CeD) is a common immune-mediated disease of the small intestine that is triggered by exposure to dietary gluten. While the HLA locus plays a major role in disease susceptibility, 39 non-HLA loci were also identified in a study of 24,2
Autor:
Christopher L. Bowlus, Sören Mucha, Piotr Milkiewicz, Jennifer G. Sambrook, Michael P. Manns, Peter R. Durie, Daniel J. Gaffney, Catalina Coltescu, Konstantinos N. Lazaridis, David Ellinghaus, Daniel Gotthardt, George F. Mells, Espen Melum, Joseph A. Odin, Mattias Laudes, Cisca Wijmenga, Kris V. Kowdley, Annarosa Floreani, Tejas S. Shah, Richard Sandford, Erik M. Schlicht, Kirsten Muri Boberg, Javier Gutierrez-Achury, Felix Braun, Martina Sterneck, Carl A. Anderson, Tom H. Karlsen, Andre Franke, Velimir A. Luketic, Brijesh Srivastava, Aliya Gulamhusein, Elizabeth C. Goode, Kelly Spiess, Gunnar Jacobs, Olivier Chazouillères, Wolfgang Lieb, Tobias Müller, Andreas Teufel, Trine Folseraas, Roger W. Chapman, Hanns-Ulrich Marschall, David J. Roberts, Christoph Schramm, Sun-Gou Ji, Albert Parés, Mariza de Andrade, Stefan Schreiber, Elizabeth J. Atkinson, Kimmo Kontula, Pietro Invernizzi, Simon M. Rushbrook, Luke Jostins, Carmel Moore, Naga Chalasani, Jimmy Z. Liu, Brian D. Juran, Willem H. Ouwehand, Graeme J.M. Alexander, John E. Eaton, Gideon M. Hirschfield, Natsuhiko Kumasaka, Martti Färkkilä, Annika Bergquist, Kapil B. Chopra, John Danesh, Bertus Eksteen, Tobias J. Weismüller, Rinse K. Weersma, Ulrich Beuers, Severine Vermeire
Publikováno v:
Nature genetics
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature genetics, 49(2), 269-273. Nature Publishing Group
Nature Genetics, 49(2), 269-273. Nature Publishing Group
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature genetics, 49(2), 269-273. Nature Publishing Group
Nature Genetics, 49(2), 269-273. Nature Publishing Group
Dipòsit Digital de la UB
Universidad de Barcelona
Primary sclerosing cholangitis (PSC) is a rare progressive disorder leading to bile duct destruction; similar to 75% of patients have comorbid inflammatory bowel disease (IBD). We undertook the largest genome-wide association study of PSC (4,796 case
Autor:
Ana Márquez, Wei-Min Chen, Alexandra Zhernakova, Isidoro González-Álvaro, Luis Rodriguez-Rodriguez, Cisca Wijmenga, Suna Onengut-Gumuscu, Stephen S. Rich, Maureen D. Mayes, Soumya Raychaudhuri, Martin Kerick, Miguel A. González-Gay, Javier Gutierrez-Achury, Javier Ibáñez
Publikováno v:
Oral Presentations.
Background In recent years, research has consistently proven the occurrence of genetic overlap across autoimmune diseases, which supports the existence of common pathogenic mechanisms in autoimmunity. Objectives The objective of this study was to fur
Autor:
Isis Ricaño-Ponce, Daria V. Zhernakova, Patrick Deelen, Oscar Luo, Xingwang Li, Aaron Isaacs, Juha Karjalainen, Jennifer Di Tommaso, Zuzanna Agnieszka Borek, Maria M. Zorro, Javier Gutierrez-Achury, Andre G. Uitterlinden, Albert Hofman, Joyce van Meurs, Mihai G. Netea, Iris H. Jonkers, Sebo Withoff, Cornelia M. van Duijn, Yang Li, Yijun Ruan, Lude Franke, Cisca Wijmenga, Vinod Kumar, Bastiaan T. Heijmans, Peter A.C. 't Hoen, Rick Jansen, Dorret I. Boomsma, René Pool, Jenny van Dongen, Jouke J. Hottenga, Marleen M.J. van Greevenbroek, Coen D.A. Stehouwer, Carla J.H. van der Kallen, Casper G. Schalkwijk, Alexandra Zhernakova, Ettje F. Tigchelaar, P. Eline Slagboom, Marian Beekman, Joris Deelen, Diana van Heemst, Jan H. Veldink, Leonard H. van den Berg, Bert A. Hofman, André G. Uitterlinden, P. Mila Jhamai, Michael Verbiest, H. Eka D. Suchiman, Marijn Verkerk, Ruud van der Breggen, Jeroen van Rooij, Nico Lakenberg, Hailiang Mei, Maarten van Iterson, Michiel van Galen, Jan Bot, Peter van 't Hof, Irene Nooren, Matthijs Moed, Martijn Vermaat, René Luijk, Marc Jan Bonder, Freerk van Dijk, Wibowo Arindrarto, Szymon M. Kielbasa, Morris A. Swertz, Erik W. van Zwet
Publikováno v:
Journal of Autoimmunity, 68, 62-74. Academic Press Inc.
Journal of Autoimmunity, 68, pp. 62-74
Journal of Autoimmunity, 68, 62-74. Elsevier Science
Journal of Autoimmunity, 68, 62-74
Journal of autoimmunity
Journal of Autoimmunity, 68, 62-74. ACADEMIC PRESS LTD-ELSEVIER SCIENCE LTD
Journal of Autoimmunity, 68, 62-74. Academic Press
Ricano-Ponce, I, Zhernakova, D V, Deelen, P, Luo, O, Li, X, Isaacs, A, Karjalainen, J, Di. Tommaso, J, Borek, Z A, Zorro, M M, Gutierrez-Achury, J, Uitterlinden, A G, Hofman, A, van Meurs, J, Boomsma, D I, Pool, R, van Dongen, J, Hottenga, J J, Neteaf, M G, Jonkers, I H, Withoff, S, van Duijn, C M, Li, Y, Ruan, Y, Franke, L, Wijmenga, C & Kumar, V 2016, ' Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs ', Journal of Autoimmunity, vol. 68, pp. 62-74 . https://doi.org/10.1016/j.jaut.2016.01.002
Journal of Autoimmunity, 68, pp. 62-74
Journal of Autoimmunity, 68, 62-74. Elsevier Science
Journal of Autoimmunity, 68, 62-74
Journal of autoimmunity
Journal of Autoimmunity, 68, 62-74. ACADEMIC PRESS LTD-ELSEVIER SCIENCE LTD
Journal of Autoimmunity, 68, 62-74. Academic Press
Ricano-Ponce, I, Zhernakova, D V, Deelen, P, Luo, O, Li, X, Isaacs, A, Karjalainen, J, Di. Tommaso, J, Borek, Z A, Zorro, M M, Gutierrez-Achury, J, Uitterlinden, A G, Hofman, A, van Meurs, J, Boomsma, D I, Pool, R, van Dongen, J, Hottenga, J J, Neteaf, M G, Jonkers, I H, Withoff, S, van Duijn, C M, Li, Y, Ruan, Y, Franke, L, Wijmenga, C & Kumar, V 2016, ' Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs ', Journal of Autoimmunity, vol. 68, pp. 62-74 . https://doi.org/10.1016/j.jaut.2016.01.002
Contains fulltext : 171367.pdf (Publisher’s version ) (Open Access) Genome-wide association and fine-mapping studies in 14 autoimmune diseases (AID) have implicated more than 250 loci in one or more of these diseases. As more than 90% of AID-associ
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1793
The MHC/HLA region has been consistently associated with a large number of complex traits, including but not limited to, most immune-mediated ones. Efforts to pinpoint drivers of this commonly encountered association peak at the short arm of chromoso
Publikováno v:
Methods in Molecular Biology ISBN: 9781493978670
The MHC/HLA region has been consistently associated with a large number of complex traits, including but not limited to, most immune-mediated ones. Efforts to pinpoint drivers of this commonly encountered association peak at the short arm of chromoso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2af7b3984e54b5a914936cff1e738303
https://doi.org/10.1007/978-1-4939-7868-7_8
https://doi.org/10.1007/978-1-4939-7868-7_8
Publikováno v:
Best practice & research in clinical gastroenterology, 29(3), 399-412. ELSEVIER SCI LTD
New insights into the underlying molecular pathophysiology of celiac disease (CeD) over the last few years have been guided by major advances in the fields of genetics and genomics. The development and use of the Immunochip genotyping platform paved
Autor:
Juha Karjalainen, Alexandra Zhernakova, Vinod Kumar, Lude Franke, Rodrigo Coutinho de Almeida, Cisca Wijmenga, Kartiek Kanduri, Anna Stachurska, Yang Li, Harm-Jan Westra, Barbara Hrdličková, Ettje F. Tigchelaar, Harri Lähdesmäki, Isis Ricaño-Ponce, Wayel H. Abdulahad, Javier Gutierrez-Achury, Marten H. Hofker, Daria V. Zhernakova, Sebo Withoff, Riitta Lahesmaa
Publikováno v:
Human Molecular Genetics, 24(2), 397-409. Oxford University Press
Although genome-wide association studies and fine mapping have identified 39 non-HLA loci associated with celiac disease (CD), it is difficult to pinpoint the functional variants and susceptibility genes in these loci. We applied integrative approach