Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Javier Garzón-Niño"'
Autor:
Pilar Sánchez-Blázquez, Elsa Cortés-Montero, María Rodríguez-Muñoz, Manuel Merlos, Javier Garzón-Niño
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-9 (2020)
Abstract The Sigma-1 receptor (σ1R) has emerged as an interesting pharmacological target because it inhibits analgesia mediated by mu-opioid receptors (MOR), and also facilitates the development of neuropathic pain. Based on these findings, the rece
Externí odkaz:
https://doaj.org/article/38f7a8e3eaaa42829080b2ae047bfd42
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 582 (2022)
The opioid peptide β-endorphin coexists in the pituitary and brain in its αN-acetylated form, which does not bind to opioid receptors. We now report that these neuropeptides exhibited opposite effects in in vivo paradigms, in which ligands of the s
Externí odkaz:
https://doaj.org/article/b76ad8eb90c64f6a9c75693c5b84bb07
Autor:
María Rodríguez-Muñoz, Elsa Cortés-Montero, Yara Onetti, Pilar Sánchez-Blázquez, Javier Garzón-Niño
Publikováno v:
Biomolecules, Vol 11, Iss 11, p 1681 (2021)
Nerve injury produces neuropathic pain through the binding of α2δ1 proteins to glutamate N-methyl-D-aspartate receptors (NMDARs). Notably, mice with a targeted deletion of the sigma 1 receptor (σ1R) gene do not develop neuropathy, whereas mice lac
Externí odkaz:
https://doaj.org/article/a1023af0b3ca4d86a48048a47e339582
Autor:
Elsa Cortés-Montero, María Rodríguez-Muñoz, M. Carmen Ruiz-Cantero, Enrique J. Cobos, Pilar Sánchez-Blázquez, Javier Garzón-Niño
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1, p 229 (2020)
Transient receptor potential ankyrin member 1 (TRPA1) belongs to the family of thermo TRP cation channels that detect harmful temperatures, acids and numerous chemical pollutants. TRPA1 is expressed in nervous tissue, where it participates in the gen
Externí odkaz:
https://doaj.org/article/5f4a02627328465e8cfddb5f0ced0149
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 1; Pages: 582
The opioid peptide β-endorphin coexists in the pituitary and brain in its αN-acetylated form, which does not bind to opioid receptors. We now report that these neuropeptides exhibited opposite effects in in vivo paradigms, in which ligands of the s
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7339 (2020)
Sigma receptor type 1 (σ1R) is a transmembrane protein expressed throughout the central nervous system and in certain peripheral tissues. The human σ1R E102Q mutation causes juvenile amyotrophic lateral sclerosis (ALS), likely by inducing a series
Externí odkaz:
https://doaj.org/article/807e3dd01683407bae8e9dfed9c39ff5
Autor:
Pilar Sánchez-Blázquez, Javier Garzón-Niño, María Rodríguez-Muñoz, Elsa Cortés-Montero, Yara Onetti
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Biomolecules
Volume 11
Issue 11
Biomolecules, Vol 11, Iss 1681, p 1681 (2021)
instname
Biomolecules
Volume 11
Issue 11
Biomolecules, Vol 11, Iss 1681, p 1681 (2021)
Nerve injury produces neuropathic pain through the binding of ¿2¿1 proteins to glutamate N-methyl-D-aspartate receptors (NMDARs). Notably, mice with a targeted deletion of the sigma 1 receptor (¿1R) gene do not develop neuropathy, whereas mice lac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fe82523931e284685daecc84861ace2
http://hdl.handle.net/10261/262100
http://hdl.handle.net/10261/262100
Autor:
Elsa Cortés-Montero, María Rodríguez-Muñoz, Pilar Sánchez-Blázquez, Manuel Merlos, Javier Garzón-Niño
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Molecular Brain, Vol 13, Iss 1, Pp 1-9 (2020)
Molecular Brain
instname
Molecular Brain, Vol 13, Iss 1, Pp 1-9 (2020)
Molecular Brain
The Sigma-1 receptor (σ1R) has emerged as an interesting pharmacological target because it inhibits analgesia mediated by mu-opioid receptors (MOR), and also facilitates the development of neuropathic pain. Based on these findings, the recent clonin
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 7339, p 7339 (2020)
Volume 21
Issue 19
Digital.CSIC. Repositorio Institucional del CSIC
instname
International Journal of Molecular Sciences, Vol 21, Iss 7339, p 7339 (2020)
Volume 21
Issue 19
Digital.CSIC. Repositorio Institucional del CSIC
instname
Sigma receptor type 1 (&sigma
1R) is a transmembrane protein expressed throughout the central nervous system and in certain peripheral tissues. The human &sigma
1R E102Q mutation causes juvenile amyotrophic lateral sclerosis (ALS), likely b
1R) is a transmembrane protein expressed throughout the central nervous system and in certain peripheral tissues. The human &sigma
1R E102Q mutation causes juvenile amyotrophic lateral sclerosis (ALS), likely b
Publikováno v:
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
instname
The 14 kDa histidine triad nucleotide-binding protein 1 (HINT1) is critical to maintain the normal function of motor neurons. Thus, a series of human HINT1 mutants cause autosomal recessive axonal neuropathy with neuromyotonia. HINT1 establishes a se