Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Javier Garcia-Hurtado"'
Autor:
Goutham Atla, Silvia Bonàs-Guarch, Mirabai Cuenca-Ardura, Anthony Beucher, Daniel J. M. Crouch, Javier Garcia-Hurtado, Ignasi Moran, the T2DSystems Consortium, Manuel Irimia, Rashmi B. Prasad, Anna L. Gloyn, Lorella Marselli, Mara Suleiman, Thierry Berney, Eelco J. P. de Koning, Julie Kerr-Conte, Francois Pattou, John A. Todd, Lorenzo Piemonti, Jorge Ferrer
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-28 (2022)
Abstract Background Non-coding genetic variants that influence gene transcription in pancreatic islets play a major role in the susceptibility to type 2 diabetes (T2D), and likely also contribute to type 1 diabetes (T1D) risk. For many loci, however,
Externí odkaz:
https://doaj.org/article/cf1281e02aac42cea7c15b4711ce5611
Autor:
Anthony Beucher, Irene Miguel-Escalada, Diego Balboa, Matías G. De Vas, Miguel Angel Maestro, Javier Garcia-Hurtado, Aina Bernal, Roser Gonzalez-Franco, Pierfrancesco Vargiu, Holger Heyn, Philippe Ravassard, Sagrario Ortega, Jorge Ferrer
The biological purpose of long non-coding RNAs (lncRNAs) is poorly understood. Haploinsufficient mutations in HNF1A homeobox A (HNF1A), encoding a homeodomain transcription factor, cause diabetes mellitus. Here, we examine HASTER, the promoter of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b9469b975430bdc6550f581cdb41e3
http://hdl.handle.net/10044/1/99697
http://hdl.handle.net/10044/1/99697
Autor:
Jorge Ferrer, Ildem Akerman, Vanessa Grau, Javier Garcia Hurtado, Philippe Ravassard, Lorenzo Piemonti, Miguel A. Maestro, Gerhard Mittler
Background: To improve cancer disparities among underrepresented minority (URM) populations, better representation of URM individuals in cancer research is needed. The San Diego State University (SDSU) and University of California San Diego (UCSD) Mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1ed33a4f7923740b1167dd1168c798b
https://doi.org/10.1101/2020.05.31.125377
https://doi.org/10.1101/2020.05.31.125377
Autor:
Ildem Akerman, Miguel Angel Maestro, Elisa De Franco, Vanessa Grau, Sarah Flanagan, Javier García-Hurtado, Gerhard Mittler, Philippe Ravassard, Lorenzo Piemonti, Sian Ellard, Andrew T. Hattersley, Jorge Ferrer
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108981- (2021)
Summary: Despite the central role of chromosomal context in gene transcription, human noncoding DNA variants are generally studied outside of their genomic location. This limits our understanding of disease-causing regulatory variants. INS promoter m
Externí odkaz:
https://doaj.org/article/282fb6a0abd54a338e19484f6b2bb305
Autor:
Joris van Arensbergen, Sebastien Dussaud, Corinne Pardanaud-Glavieux, Javier García-Hurtado, Claire Sauty, Aline Guerci, Jorge Ferrer, Philippe Ravassard
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171508 (2017)
Lineage-selective expression of developmental genes is dependent on the interplay between activating and repressive mechanisms. Gene activation is dependent on cell-specific transcription factors that recognize transcriptional enhancer sequences. Gen
Externí odkaz:
https://doaj.org/article/3977ac1a93c14599a412c77fb7b4962b