Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Javier G. Osende"'
Autor:
Lourdes Encinas, Montserrat Ortega-Guerra, Ana Guardia, Joaquín Rullas, Esther Porras de Francisco, Juan Miguel-Siles, Cristina Rivero, Jorge Esquivias, Matthew H. Todd, Carlos Alemparte, Setshaba D. Khanye, Jessica Baiget, Raquel Vida Fernández, Winston Nxumalo, María Teresa Fraile-Gabaldón, Peter J. Rutledge, Esther Pérez-Herrán, Javier G. Osende, Modesto J. Remuiñán, Katrina A. Badiola, Marta León Alonso, Arancha Pérez, Ilaria Giordano, Elena Jimenez, Monica Cacho, Fátima Ortega
Publikováno v:
Journal of medicinal chemistry. 61(24)
Society urgently needs new, effective medicines for the treatment of tuberculosis. To kick-start the required hit-to-lead campaigns, the libraries of pharmaceutical companies have recently been evaluated for starting points. The GlaxoSmithKline (GSK)
Autor:
Reyhan Irfan, Carl Young, Christopher Beattie, Michael North, Javier G. Osende, Ross W. Harrington, Thilo Baronsky
Publikováno v:
ACS Catalysis. 3:790-797
The bimetallic aluminum(salen) complex [Al(salen)]2O is shown to catalyze the synthesis of oxazolidinones from epoxides and isocyanates. The reaction is demonstrated to proceed with overall retention of epoxide stereochemistry, and both aromatic and