Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Javier E. Stern"'
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108243- (2023)
Summary: Neuropeptides are packed into large dense core vesicles (LDCVs) that are transported from the soma out into their processes. Limited information exists regarding mechanisms regulating LDCV trafficking, particularly during challenges to bodil
Externí odkaz:
https://doaj.org/article/8086a6849ee34278a14732ec6ae1838f
Autor:
Mai Iwasaki, Arthur Lefevre, Ferdinand Althammer, Etienne Clauss Creusot, Olga Łąpieś, Hugues Petitjean, Louis Hilfiger, Damien Kerspern, Meggane Melchior, Stephanie Küppers, Quirin Krabichler, Ryan Patwell, Alan Kania, Tim Gruber, Matthew K. Kirchner, Moritz Wimmer, Henning Fröhlich, Laura Dötsch, Jonas Schimmer, Sabine C. Herpertz, Beate Ditzen, Christian P. Schaaf, Kai Schönig, Dusan Bartsch, Anna Gugula, Aleksandra Trenk, Anna Blasiak, Javier E. Stern, Pascal Darbon, Valery Grinevich, Alexandre Charlet
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
The hypothalamic neuropeptide oxytocin exerts analgesic effects, but the underlying pathways remain largely elusive. Here, the authors describe an analgesic pathway formed by oxytocin neurons projecting to the periaqueductal grey, where axonally rele
Externí odkaz:
https://doaj.org/article/85fa7e14fa3741ae8af552981e58801d
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
It is generally assumed that dendritic release of neuropeptides from magnocellular neurosecretory neurons (MNNs), a critical process involved in homeostatic functions, is an activity-dependent process that requires backpropagating action potentials (
Externí odkaz:
https://doaj.org/article/cfc00cdf157f4c81bf27580251694a55
Autor:
Ferdinand Althammer, Eric G. Krause, Anette D. de Kloet, Justin Smith, Valery Grinevich, Alexandre Charlet, Javier E. Stern
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101160- (2022)
Summary: Here, we present a step-by-step protocol for three-dimensional reconstruction of astrocyte morphology, applied to the central amygdala oxytocin receptor-expressing astrocytes. This includes RNAse-free perfusion, combination of RNAscope and i
Externí odkaz:
https://doaj.org/article/4ddad5276e15406fb78657ab964df402
Autor:
Michael R. Perkinson, Matthew K. Kirchner, Meng Zhang, Rachael A. Augustine, Javier E. Stern, Colin H. Brown
Publikováno v:
Physiological Reports, Vol 10, Iss 6, Pp n/a-n/a (2022)
Abstract Oxytocin is secreted into the periphery by magnocellular neurons of the hypothalamic supraoptic and paraventricular nuclei (SON and PVN) to trigger uterine contraction during birth and milk ejection during suckling. Peripheral oxytocin secre
Externí odkaz:
https://doaj.org/article/623ea8b5aac4421f9c30b0f28c849372
Autor:
Ferdinand Althammer, Hildebrando Candido Ferreira-Neto, Myurajan Rubaharan, Ranjan K. Roy, Atit A. Patel, Daniel N. Cox, Javier E. Stern
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-19 (2020)
Abstract Background Cardiovascular diseases, including heart failure, are the most common cause of death globally. Recent studies support a high degree of comorbidity between heart failure and cognitive and mood disorders resulting in memory loss, de
Externí odkaz:
https://doaj.org/article/5dc52cfc25e549bd962955445536ae20
Autor:
Ranjan K. Roy, Ferdinand Althammer, Alexander J. Seymour, Wenting Du, Vinicia C. Biancardi, Jordan P. Hamm, Jessica A. Filosa, Colin H. Brown, Javier E. Stern
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109925- (2021)
Summary: Neurovascular coupling (NVC), the process that links neuronal activity to cerebral blood flow changes, has been mainly studied in superficial brain areas, namely the neocortex. Whether the conventional, rapid, and spatially restricted NVC re
Externí odkaz:
https://doaj.org/article/0f6ae9760d764ee28bc97bde1ff6691a
Autor:
Chun-Xia Yi, Marc Walter, Yuanqing Gao, Soledad Pitra, Beata Legutko, Stefanie Kälin, Clarita Layritz, Cristina García-Cáceres, Maximilian Bielohuby, Martin Bidlingmaier, Stephen C. Woods, Alexander Ghanem, Karl-Klaus Conzelmann, Javier E. Stern, Martin Jastroch, Matthias H. Tschöp
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Long-term consumption of a calorie-rich diet persistently activates brain microglia. Here, the authors show that microglial activity in mouse brains oscillates daily in conjunction with feeding, and that TNFα, secreted by activated microglia, induce
Externí odkaz:
https://doaj.org/article/6cf55e31e14747279bd3ace341933215
Autor:
Ferdinand Althammer, Hildebrando Candido Ferreira-Neto, Myurajan Rubaharan, Ranjan K. Roy, Atit A. Patel, Anne Murphy, Daniel N. Cox, Javier E. Stern
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/b00cd54f97cc4bf997c36624f6b7b9b8
Mechanisms underlying prorenin actions on hypothalamic neurons implicated in cardiometabolic control
Publikováno v:
Molecular Metabolism, Vol 5, Iss 10, Pp 858-868 (2016)
Background: Hypertension and obesity are highly interrelated diseases, being critical components of the metabolic syndrome. Despite the growing prevalence of this syndrome in the world population, efficient therapies are still missing. Thus, identifi
Externí odkaz:
https://doaj.org/article/3d303abb45e5487982f7a39ccc37cca8